Transport and sorting of sphingolipids in polarized cells: the involvement of the sub-apical compartment

Research output: ThesisThesis fully internal (DIV)

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Abstract

The work described in this thesis has provided a novel insight into the process of sphingolipid transport and sorting in polarized cells. We have used HepG2 cells as a model system to study polarized traffic in hepatic cells. Under specific culture conditions, HepG2 cells acquire a polarized phenotype, displaying a sinusoidal, basolateral plasma membrane and a bilecanalicular, apical plasma membrane domain ... Zie; Summary
Original languageEnglish
QualificationDoctor of Philosophy
Publisher
Publication statusPublished - 1999

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