Treatment and survival of patients with small-cell lung cancer: small steps forward, but not for patients > 80

M. L. G. Janssen-Heijnen; H. A. A. M. Maas; S. Siesling; C. C. E. Koning; J. W. W. Coebergh; H. J. M. Groen

doi:10.1093/annonc/mdr303

Treatment and survival of patients with small-cell lung cancer: small steps forward, but not for patients > 80

M. L. G. Janssen-Heijnen^*
, H. A. A. M. Maas
, S. Siesling
, C. C. E. Koning
, J. W. W. Coebergh
, H. J. M. Groen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

25 Citations (Scopus)

Abstract

Background: Seventy-five percent of newly diagnosed patients with small-cell lung cancer (SCLC) are aged 60+ and quite a few are treated less aggressively because of fear of toxic effects. We described trends in treatment and survival of unselected SCLC patients.

Patients and methods: For the present study, all 13 007 SCLC patients aged 60+ diagnosed in The Netherlands from 1997 to 2007 were included.

Results: Among patients with limited disease, the proportion receiving chemoradiation increased from 35% to almost 60% for those aged 60-69, from 28% to 48% in age group 70-74, from 17% to 33% in age group 75-79, but remained

Conclusions: CT (+radiotherapy) has improved survival for unselected SCLC patients

Original language	English
Pages (from-to)	954-960
Number of pages	7
Journal	Annals of Oncology
Volume	23
Issue number	4
DOIs	https://doi.org/10.1093/annonc/mdr303
Publication status	Published - Apr-2012

Keywords

elderly
population-based
small-cell lung cancer
survival
treatment
trends
END RESULTS DATABASE
CHANGING EPIDEMIOLOGY
AGE
CHEMOTHERAPY
COMORBIDITY
DISEASE
SURVEILLANCE
NETHERLANDS
MANAGEMENT
CARCINOMA

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@article{8619279ec5fb457f8f04ae51f59f963c,

title = "Treatment and survival of patients with small-cell lung cancer: small steps forward, but not for patients > 80",

abstract = "Background: Seventy-five percent of newly diagnosed patients with small-cell lung cancer (SCLC) are aged 60+ and quite a few are treated less aggressively because of fear of toxic effects. We described trends in treatment and survival of unselected SCLC patients.Patients and methods: For the present study, all 13 007 SCLC patients aged 60+ diagnosed in The Netherlands from 1997 to 2007 were included.Results: Among patients with limited disease, the proportion receiving chemoradiation increased from 35\% to almost 60\% for those aged 60-69, from 28\% to 48\% in age group 70-74, from 17\% to 33\% in age group 75-79, but remainedConclusions: CT (+radiotherapy) has improved survival for unselected SCLC patients",

keywords = "elderly, population-based, small-cell lung cancer, survival, treatment, trends, END RESULTS DATABASE, CHANGING EPIDEMIOLOGY, AGE, CHEMOTHERAPY, COMORBIDITY, DISEASE, SURVEILLANCE, NETHERLANDS, MANAGEMENT, CARCINOMA",

author = "Janssen-Heijnen, \{M. L. G.\} and Maas, \{H. A. A. M.\} and S. Siesling and Koning, \{C. C. E.\} and Coebergh, \{J. W. W.\} and Groen, \{H. J. M.\}",

year = "2012",

month = apr,

doi = "10.1093/annonc/mdr303",

language = "English",

volume = "23",

pages = "954--960",

journal = "Annals of Oncology",

issn = "0923-7534",

publisher = "Oxford University Press",

number = "4",

}

TY - JOUR

T1 - Treatment and survival of patients with small-cell lung cancer

T2 - small steps forward, but not for patients > 80

AU - Janssen-Heijnen, M. L. G.

AU - Maas, H. A. A. M.

AU - Siesling, S.

AU - Koning, C. C. E.

AU - Coebergh, J. W. W.

AU - Groen, H. J. M.

PY - 2012/4

Y1 - 2012/4

N2 - Background: Seventy-five percent of newly diagnosed patients with small-cell lung cancer (SCLC) are aged 60+ and quite a few are treated less aggressively because of fear of toxic effects. We described trends in treatment and survival of unselected SCLC patients.Patients and methods: For the present study, all 13 007 SCLC patients aged 60+ diagnosed in The Netherlands from 1997 to 2007 were included.Results: Among patients with limited disease, the proportion receiving chemoradiation increased from 35% to almost 60% for those aged 60-69, from 28% to 48% in age group 70-74, from 17% to 33% in age group 75-79, but remainedConclusions: CT (+radiotherapy) has improved survival for unselected SCLC patients

AB - Background: Seventy-five percent of newly diagnosed patients with small-cell lung cancer (SCLC) are aged 60+ and quite a few are treated less aggressively because of fear of toxic effects. We described trends in treatment and survival of unselected SCLC patients.Patients and methods: For the present study, all 13 007 SCLC patients aged 60+ diagnosed in The Netherlands from 1997 to 2007 were included.Results: Among patients with limited disease, the proportion receiving chemoradiation increased from 35% to almost 60% for those aged 60-69, from 28% to 48% in age group 70-74, from 17% to 33% in age group 75-79, but remainedConclusions: CT (+radiotherapy) has improved survival for unselected SCLC patients

KW - elderly

KW - population-based

KW - small-cell lung cancer

KW - survival

KW - treatment

KW - trends

KW - END RESULTS DATABASE

KW - CHANGING EPIDEMIOLOGY

KW - AGE

KW - CHEMOTHERAPY

KW - COMORBIDITY

KW - DISEASE

KW - SURVEILLANCE

KW - NETHERLANDS

KW - MANAGEMENT

KW - CARCINOMA

U2 - 10.1093/annonc/mdr303

DO - 10.1093/annonc/mdr303

M3 - Article

SN - 0923-7534

VL - 23

SP - 954

EP - 960

JO - Annals of Oncology

JF - Annals of Oncology

IS - 4

ER -

Treatment and survival of patients with small-cell lung cancer: small steps forward, but not for patients > 80

Abstract

Keywords

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