Two cases of subcutaneous Scedosporium apiospermum infection treated with voriconazole

F. Bosma; A. Voss; H. W. van Hamersvelt; R. G.L. de Sévaux; J. Biert; B. J. Kullberg; W. G.J. Melchers; P. E. Verweij

doi:10.1046/j.1469-0691.2003.00596.x

Two cases of subcutaneous Scedosporium apiospermum infection treated with voriconazole

F. Bosma^*, A. Voss, H. W. van Hamersvelt, R. G.L. de Sévaux, J. Biert, B. J. Kullberg, W. G.J. Melchers, P. E. Verweij

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Scedosporium apiospermum is a mold that is increasingly being recognized as an opportunistic pathogen in immunocompromised patients, and treatment is complicated by intrinsic resistance to several antifungal agents. In our hospital, two cases of S. apiospermum infection occurring within 2 weeks were successfully treated with voriconazole. Since both patients were infected with an uncommon pathogen, a search for a common nosocomial source was performed. As environmental cultures yielded no S. apiospermum, and random amplified polymorphic DNA (RAPD) fingerprinting showed that the patients' strains were genotypically unrelated, we considered a common nosocomial source of S. apiospermum to be unlikely.

Original language	English
Pages (from-to)	750-753
Number of pages	4
Journal	Clinical Microbiology and Infection
Volume	9
Issue number	7
DOIs	https://doi.org/10.1046/j.1469-0691.2003.00596.x
Publication status	Published - 1-Jul-2003
Externally published	Yes

Keywords

Fingerprinting
Scedosporium apoispermum
Voriconazole

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10.1046/j.1469-0691.2003.00596.xLicence: Elsevier

Two cases of subcutaneous Scedosporium apiospermum infection treated with voriconazoleFinal publisher's version, 167 KBLicence: Taverne

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Cite this

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title = "Two cases of subcutaneous Scedosporium apiospermum infection treated with voriconazole",

abstract = "Scedosporium apiospermum is a mold that is increasingly being recognized as an opportunistic pathogen in immunocompromised patients, and treatment is complicated by intrinsic resistance to several antifungal agents. In our hospital, two cases of S. apiospermum infection occurring within 2 weeks were successfully treated with voriconazole. Since both patients were infected with an uncommon pathogen, a search for a common nosocomial source was performed. As environmental cultures yielded no S. apiospermum, and random amplified polymorphic DNA (RAPD) fingerprinting showed that the patients' strains were genotypically unrelated, we considered a common nosocomial source of S. apiospermum to be unlikely.",

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AU - Bosma, F.

AU - Voss, A.

AU - van Hamersvelt, H. W.

AU - de Sévaux, R. G.L.

AU - Biert, J.

AU - Kullberg, B. J.

AU - Melchers, W. G.J.

AU - Verweij, P. E.

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AB - Scedosporium apiospermum is a mold that is increasingly being recognized as an opportunistic pathogen in immunocompromised patients, and treatment is complicated by intrinsic resistance to several antifungal agents. In our hospital, two cases of S. apiospermum infection occurring within 2 weeks were successfully treated with voriconazole. Since both patients were infected with an uncommon pathogen, a search for a common nosocomial source was performed. As environmental cultures yielded no S. apiospermum, and random amplified polymorphic DNA (RAPD) fingerprinting showed that the patients' strains were genotypically unrelated, we considered a common nosocomial source of S. apiospermum to be unlikely.

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DO - 10.1046/j.1469-0691.2003.00596.x

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