Type B Aortic Dissection After the Use of Tadalafil

Charlotte M. Lameijer, Ignace F. J. Tielliu, Mels F. van Driel, Clark J. Zeebregts*

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review

3 Citations (Scopus)


A 63-year-old male patient with a type B aortic dissection after the use of tadalafil, a phosphodiesterase type 5 inhibitor, is presented. The possible role of a novel predisposing factor-sexual activity combined with tadalafil-is reviewed. This report and three other cases add a new dimension to the known predisposing factors such as chronic systemic hypertension, hereditary connective tissue diseases-and congenital aortic valve diseases. However, the precise role of phosphodiesterase type 5 inhibitors in the pathophysiology of aortic dissection remains unknown. (Ann Thorac Surg 2012;93:651-3) (C) 2012 by The Society of Thoracic Surgeons

Original languageEnglish
Pages (from-to)651-653
Number of pages3
JournalAnnals of thoracic surgery
Issue number2
Publication statusPublished - Feb-2012



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