Our findings also illustrate that heterogeneity between cohort studies can be challenging for multi-cohort research. The main advantages of using multiple cohort studies were the very large sample sizes, broad exposure ranges, and the ability to make comparisons across cohorts. In our study populations, exposure to traffic-related noise and air pollution was not consistently associated with our study outcomes. These findings are meaningful because they show us to be cautious with interpreting results from a single cohort study. The use of data from multiple cohort studies provides excellent opportunities for studying harmful environmental exposures. The scientific community should invest in the sharing and harmonization of their cohort data, supporting research on large geographical scales.
|Qualification||Doctor of Philosophy|
|Place of Publication||[Groningen]|
|Publication status||Published - 2016|
Bakker, S. (Creator), Dotinga, A. (Creator), Vonk, J. (Creator), Smidt, N. (Creator), Scholtens, S. (Creator), Swertz, M. (Creator), Wijmenga, C. (Creator), Wolffenbuttel, B. (Creator), Stolk, R. (Creator), van Zon, S. (Creator), Rosmalen, J. (Creator), Postma, D. (Creator), de Boer, R. (Creator), Navis, G. (Creator), Slaets, J. (Creator), Ormel, H. (Creator), van Dijk, F. (Creator) & Bolmer, B. (Data Manager), Lifelines, 2006