Urothelial Cell Carcinoma: Patterns of care and contemporary urography

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    Abstract

    This thesis focuses on the outcome of diagnosis and treatment of urothelial cell carcinoma (UCC). Depending on the location it is mentioned bladder cancer respectively Upper Urinary Tract Tumor (UUTT).
    The first part of this thesis attends to bladder cancer care in different regions of the Netherlands at the time that only European and American guidelines were available. The pattern of care for patients with high risk Non Muscle Invasive Bladder Carcinoma (NMIBC) as well as Muscle Invasive Bladder Cancer (MIBC) are evaluated to assess the impact of patient-, tumor- and doctor-related factors on treatment choices and treatment outcome. Increasing age and more comorbidity seem to be important determinating factors for not undergoing the recommended treatment.
    The second part of the thesis deals with the visualization of the upper urinary tract (UUT) with regard to the diagnosis and treatment of UUTT. The history and background of the different urographic techniques are discussed in detail. Today CT scanning with intravenous contrast (CTU) is most frequently used. Although not routinely performed in most urological clinics, Retrograde Ureteric Pyelography (RUP) still plays a significant role in our center, especially because of the excellent X-ray facilities during the last four decennia. One study evaluates the feasibility and efficacy of RUP in the diagnosis of UCC of the UUT and compares the grade of opacification of RUP with that of CTU. The second one focuses on the early detection of UUTT using RUP urography in patients with proven urothelial cell carcinoma.
    Translated title of the contributionUrotheelcel Carcinoom: Zorgpatronen en hedendaagse urografie
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    Supervisors/Advisors
    • de Jong, Igle Jan, Supervisor
    • de Bock, Truuske, Supervisor
    • Gietema, Jourik, Assessment committee
    • Buskens, Erik, Assessment committee
    • De la Rosette, Jean, Assessment committee, External person
    Award date29-Oct-2014
    Publisher
    Print ISBNs978-90-367-7200-6
    Electronic ISBNs978-90-367-7199-3
    Publication statusPublished - 2014

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