Validation of the Measurement of Intra-abdominal Fat Between Ultrasound and CT Scan in Women with Obesity and Infertility

Walter K. H. Kuchenbecker*, Henk Groen, Heleen Pel, Johanna H. T. Bolster, Bruce H. R. Wolffenbuttel, Jolande A. Land, Annemieke Hoek, Eva Corpeleijn

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Abstract

Objective: To compare the means and changes over time of intra-abdominal fat (IAF) and subcutaneous abdominal fat (SAF) measured by abdominal ultrasound (US) and computerized tomography (CT).

Design and Methods: Prospective cohort study of 53 women with obesity and infertility undergoing a lifestyle program.

Results: The Pearson's correlation between IAF measurement by US compared to CT was good at baseline, month 3 and 6 (all r >= 0.72). The correlation of SAF measurement by US compared to CT was reasonable at baseline (r = 0.54; 95%CI 0.30-0.78) and weak at month 3 and 6 (all r 0.48). US could not measure the changes of SAF over time. The Bland-Altman plot showed good agreement between US and CT for IAF measurements (-1.1 [95%CI - 3.9-1.6] cm lower mean in US) at baseline. For changes of IAF over time, mean estimates were in agreement.

Conclusion: In women with obesity and infertility, measuring IAF by US is in good agreement with the CT scan methodology but the measurement of SAF by US is unreliable.

Original languageEnglish
Pages (from-to)537-544
Number of pages8
JournalObesity
Volume22
Issue number2
DOIs
Publication statusPublished - Feb-2014

Keywords

  • POLYCYSTIC-OVARY-SYNDROME
  • ADIPOSE-TISSUE
  • ABDOMINAL ADIPOSITY
  • METABOLIC SYNDROME
  • MEASUREMENT SITE
  • VISCERAL FAT
  • RISK
  • PREGNANCY
  • ULTRASONOGRAPHY
  • REPRODUCTION

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