Value and limitations of electromechanical endocardial mapping in the assessment of global and regional left ventricular function and transmural extent of infarction: a comparison with cardiovascular magnetic resonance

Pieter A. van der Vleuten*, Robin Nijveldt, Eng-Shiong Tan, Rene A. Tio, Albert C. van Rossum, Felix Zijlstra

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    4 Citations (Scopus)

    Abstract

    Aims: To determine the relation between electromechanical endocardial mapping (EEM) and cardiac magnetic resonance (CMR) derived functional and viability parameters in patients with a large myocardial infarction.

    Methods and results: Forty-two patients with a large ST-elevation myocardial infarction underwent both EEM and CMR four months after primary percutaneous coronary intervention. EEM was performed to assess linear local shortening (LLS), unipolar voltage (UV) and bipolar voltage (BV). CMR cine imaging was performed to determine left ventricular global volumes, ejection fraction and regional function. Late gadolinium enhancement was used to assess size and transmural extent of infarction. Average LLS, UV and BV differed significantly between normal and dysfunctional segments (9.8 vs. 7.3, 11.8 vs. 9.7 and 3.3 vs. 2.8 for LLS, UV and BV respectively; p

    Conclusions: EEM may be helpful in determining both the regional function and the transmural extent of infarction in patients with a large myocardial infarction. However, correlation with CMR parameters was moderate and exact cut-off values for EEM parameters could not be established. Further development of this potentially very useful modality is needed before it can be advocated for exact border-zone endocardial injection.

    Original languageEnglish
    Pages (from-to)616-622
    Number of pages7
    JournalEurointervention
    Volume6
    Issue number5
    Publication statusPublished - Nov-2010

    Keywords

    • Endocardial map
    • magnetic resonance imaging
    • NOGA
    • CORONARY-ARTERY-DISEASE
    • ISCHEMIC-HEART FAILURE
    • MYOCARDIAL VIABILITY
    • INTRAMYOCARDIAL INJECTION
    • QUANTITATIVE ASSESSMENT
    • EJECTION FRACTION
    • CELLS
    • REVASCULARIZATION
    • CARDIOMYOPATHY
    • INTERVENTION

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