VASCULAR COMPROMISE PRIOR TO INTESTINAL MANIFESTATIONS OF CROHNS-DISEASE IN A 14-YEAR-OLD GIRL

RM VANELBURG*, EL HENAR, CMA BIJLEVELD, TR PRINS, HSA HEYMANS

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    19 Citations (Scopus)

    Abstract

    Vascular manifestations as extraintestinal symptoms of Crohn's disease are rare and only occasionally reported in children. A 14-year-old girl with vascular compromise prior to intestinal manifestations of Crohn's disease is described. The vascular symptoms were due to segmental narrowing of several major arteries as shown by angiography. This kind of vascular involvement in our patient is different from the pattern described in Crohn's disease and resembles Takayasu's disease. Recently, it has been suggested that Crohn's disease could be mediated by multifocal gastrointestinal infarction due to chronic focal mesenteric arteritis at the level of the muscularis propria of the gut. In Takayasu's disease, a granulomatous inflammation of the vasa vasorum of affected vessels is frequently found. An intramural arteritis, granulomatous in nature, could be the common pathway in both Crohn's and Takayasu's diseases. Until the etiologies of both diseases are uncovered, the interrelation between them will remain subject to speculation.

    Original languageEnglish
    Pages (from-to)97-100
    Number of pages4
    JournalJournal of Pediatric Gastroenterology and Nutrition
    Volume14
    Issue number1
    Publication statusPublished - Jan-1992

    Keywords

    • TAKAYASU DISEASE
    • CROHNS DISEASE
    • CHILDHOOD
    • INFLAMMATORY BOWEL-DISEASE
    • TAKAYASUS ARTERITIS
    • CHILDREN
    • COMPLICATIONS

    Cite this