Waist circumference and VO2max are associated with metabolic and hemostatic risk in premenopausal nurses

H Elich*, H Riese, EJC De Geus

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

In 21 nurses (34.4+/-3.9 yr), VO2max, physical activity, body composition and lifestyle parameters were measured to determine which of these characteristics are related to metabolic and hemostatic risk for cardiovascular disease. Physical activity was assessed with the 7-day recall interview VO2max was measured in a progressive and continuous treadmill test to volitional fatigue. Fasting insulin, total cholesterol, HDL-C, triglycerides, fibrinogen, tPA-act, tPA-ag, and PAI-1-ag were determined from fasting blood samples. Contrary to our expectation, there was no association of physical activity with any of these risk indicators. High VO2max was associated with lower levels of insulin and fibrinogen. Regression analyses indicated that metabolic and hemostatic risk indicators, as measured in healthy premenopausal nurses, were mainly predicted by waist circumference and oral contraceptive use.

Original languageEnglish
Pages (from-to)228-235
Number of pages8
JournalScandinavian Journal of Medicine & Science in Sports
Volume10
Issue number4
Publication statusPublished - Aug-2000

Keywords

  • CORONARY HEART-DISEASE
  • DENSITY-LIPOPROTEIN CHOLESTEROL
  • TISSUE-PLASMINOGEN-ACTIVATOR
  • INSULIN-RESISTANCE SYNDROME
  • PHYSICAL-ACTIVITY
  • CARDIOVASCULAR-DISEASE
  • CARDIORESPIRATORY FITNESS
  • FIBRINOLYTIC-ACTIVITY
  • ORAL-CONTRACEPTIVES
  • PLASMA-LIPOPROTEINS

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