Wiener kernel analysis of inner ear function in the American bullfrog

Pim Van Dijk*, Hero P. De Wit, Johannes M. Segenhout, Arnold Tubis

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    36 Citations (Scopus)

    Abstract

    The response of 17 primary auditory nerve fibers in the American bullfrog (Rana catesbeiana) to acoustic noise stimulation of the tympanic membrane was recorded. For each fiber, the first- and second-order Wiener kernels, k(1)(tau(1)) and k(2)(tau(1),tau(2)), were computed by cross correlation of the stimulus and the response. The kernels revealed amplitude and phase characteristics of auditory filters of both phase-locking and non-phase-locking fibers. Wiener kernels of high- and midfrequency fibers (best frequency, BF>500 Hz), implied a simple sandwich model, consisting of a cascade of a linear bandpass filter, a static nonlinearity, a linear low-pass filter, and a spike generator. The bandpass filter was at least of order 7, and had a linear phase response, for both the high- and the midfrequency fibers. Averaged across fibers, filter order 2, and cutoff frequency 451 Hz for the second filter in the model was observed. The responses of low-frequency fibers (BF<500 Hz) could not be fit with the sandwich model, because the Fourier transform K-2(f(1),f(2)) of the second-order Wiener kernel showed significant components at off-diagonal frequencies f(1) not equal+/-f(2). The presence of these off-diagonal components shows that, in addition to the phase and gain characteristics of auditory filters, the Wiener kernel analysis reveals nonlinear two-tone interactions.

    Original languageEnglish
    Pages (from-to)904-919
    Number of pages16
    JournalJournal of the Acoustical Society of America
    Volume95
    Issue number2
    DOIs
    Publication statusPublished - Feb-1994

    Keywords

    • PERIPHERAL AUDITORY-SYSTEM
    • NERVE-FIBERS
    • RANA-CATESBEIANA
    • SYNCHRONIZATION
    • SENSITIVITIES
    • SELECTIVITY
    • RESPONSES
    • NEURONS
    • PAPILLA

    Fingerprint

    Dive into the research topics of 'Wiener kernel analysis of inner ear function in the American bullfrog'. Together they form a unique fingerprint.

    Cite this