Working Mechanisms of Exposure and Response Prevention in the Treatment of Tourette Syndrome and Tic Disorders Revisited: No Evidence for within-Session Habituation to Premonitory Urges

Jolande M.T.M. van de Griendt*, Nelleke M.E. van den Berg, Cara W.J. Verdellen, Daniëlle C. Cath, Marc J.P.M. Verbraak

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    25 Downloads (Pure)

    Abstract

    Background: Exposure and response prevention (ERP) has been shown to be an effective treatment for Tourette syndrome (TS) and chronic tic disorders (CTD). ERP is based on voluntary tic suppression in combination with prolonged exposure to premonitory urges preceding tics. A prevailing hypothesis of the working mechanism underlying ERP in tics is habituation to the premonitory urges as a result of prolonged exposure. However, results so far are equivocal. This study aims to further explore the relation between urges and ERP in tics, by investigating the course of premonitory urges during ERP sessions.

    Methods: Using a data-driven approach, within-session habituation to premonitory urge intensity was investigated. In total, 29 TS patients rated urge intensity at seven timepoints during ten 1 h ERP sessions.

    Results/Conclusions: Latent growth modeling showed an increase in urge intensity during the first 15 min of each session followed by a plateau in the remaining 45 min of the session. This does not support the idea of within-session habituation to premonitory urges as a working mechanism of ERP. Other potential underlying working mechanisms are discussed and should be tested in future research.

    Original languageEnglish
    Article number7087
    Number of pages12
    JournalJournal of Clinical Medicine
    Volume12
    Issue number22
    DOIs
    Publication statusPublished - Nov-2023

    Keywords

    • behavior therapy
    • exposure and response prevention (ERP)
    • habituation
    • premonitory urge
    • Tourette syndrome

    Fingerprint

    Dive into the research topics of 'Working Mechanisms of Exposure and Response Prevention in the Treatment of Tourette Syndrome and Tic Disorders Revisited: No Evidence for within-Session Habituation to Premonitory Urges'. Together they form a unique fingerprint.

    Cite this