Description
The paradox of the organism refers to the observation that organisms persist as seemingly coherent entities with the singular agenda of maximizing fitness, despite the potential for intra-organismal elements such as genes and cells to hold and pursue conflicting agendas. Quantifying to what extent such intra-organismal conflict actually threatens the integrity of the organism and its ability to pursue fitness maximization requires the development of a mathematical framework that relates the agenda of the organism to the potentially-conflicting agendas of its constituent parts. Here, I will discuss which mechanisms contribute to intra-organismal entities having shared versus disparate agendas, and to which extent disparate agendas and the mechanisms of pursuing them represent a threat to organismal integrity. The resulting insights are used to discuss a preliminary framework for quantifying the paradox of the organism.Periode | 8-nov.-2022 |
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Evenementstitel | The Paradox of the Organism (Revisited) |
Evenementstype | Conference |
Locatie | Washington, United States, District of ColumbiaToon op kaart |
Mate van erkenning | International |
Documenten & links
Gerelateerde inhoud
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Onderzoeksoutput
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Adaptation in the face of internal conflict: The paradox of the organism revisited
Onderzoeksoutput › Academic › peer review
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Projecten
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Adaptive Life
Project: Research