Description

The department of Gastroenterology and Hepatology of the University Medical Center Groningen initiated the 1000IBD project to prospectively follow more than a 1000 IBD patients from the Northern provinces of the Netherlands. We have collected a uniquely large number of phenotypes and generated multi-omics profiles for these patients. To date, 1,215 participants have been enrolled in the 1000IBD project, and enrolment is on-going. Patients that participate in the 1000IBD project are followed prospectively and the phenotype data includes information on dietary and environmental factors, and drug response. Genome information has been generated using genotyping (ImmunoChip, Global Screening Array, and HumanExomeChip), and sequencing (whole exome sequencing, and targeted resequencing of IBD susceptibility loci), transcriptome information generated using RNA-sequencing of intestinal biopsies, and microbiome information generated using both sequencing of the 16S rRNA gene and whole genome shotgun metagenomic sequencing.,Data categories: Biological samples, Medical records, Physiological/Biochemical measurements, Survey data
Material collected: Feaces
Experimental data: Genomics, Transcriptomics, Other
Number of donors: 1000
Sex: Female, Male
Age: 18-85 Year
Diseases studied: Noninfective enteritis and colitis,
Datum van beschikbaarheid1-jan-2019
UitgeverUniversity of Groningen

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