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Additional file 1 of Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

  • Patrice Perron (Contributor)
  • Nour Baiz (Contributor)
  • Hongmei Zhang (Contributor)
  • Per Magnus (Contributor)
  • Darina Czamara (Contributor)
  • Pooja Jain (Contributor)
  • Karen Huen (Contributor)
  • Harold Snieder (Contributor)
  • Priyadarshini Kachroo (Contributor)
  • Isabella Annesi-Maesano (Contributor)
  • Eva Corpeleijn (Contributor)
  • Sheryl L Rifas-Shiman (Contributor)
  • Terence Dwyer (Contributor)
  • Petter Brodin (Contributor)
  • John W. Holloway (Contributor)
  • Judith Vonk (Contributor)
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  • Elisabeth B. Binder (Contributor)
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  • Leanne K. Küpers (Wageningen University, Univ Bristol, University of Bristol, HH Wills Phys Lab) (Contributor)

Dataset

Description

Table S1. Cohort-specific results from epigenome-wide association analyses of gestational age. Table S2. Normalization technique and phenotype definitions used by each cohort. Table S3. Bonferroni-significant CpGs from the meta-analysis on the association between continuous gestational age (no complications model) and offspring DNA methylation at birth adjusted for estimated cell counts. Table S4. Bonferroni-significant CpGs from the meta-analysis on the association between continuous gestational age (all births model) and offspring DNA methylation at birth adjusted for estimated cell counts. Table S5. Gene regions that had at least three consecutive Bonferroni significant CpG sites from the continuous gestational age analyses (no complications model). Table S6. DMRs (n = 2375) for gestational age in relation to newborn methylation (no complication model) identified by using both comb-p (P
Datum van beschikbaarheid2-mrt.-2020
UitgeverUniversity of Groningen

Contact

  • Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

    Merid, S. K., Novoloaca, A., Sharp, G. C., Kupers, L. K., Kho, A. T., Roy, R., Gao, L., Annesi-Maesano, I., Jain, P., Plusquin, M., Kogevinas, M., Allard, C., Vehmeijer, F. O., Kazmi, N., Salas, L. A., Rezwan, F. I., Zhang, H., Sebert, S., Czamara, D. & Rifas-Shiman, S. L. & 73 anderen, Melton, P. E., Lawlor, D. A., Pershagen, G., Breton, C. V., Huen, K., Baiz, N., Gagliardi, L., Nawrot, T. S., Corpeleijn, E., Perron, P., Duijts, L., Nohr, E. A., Bustamante, M., Ewart, S. L., Karmaus, W., Zhao, S., Page, C. M., Herceg, Z., Jarvelin, M.-R., Lahti, J., Baccarelli, A. A., Anderson, D., Kachroo, P., Relton, C. L., Bergstrom, A., Eskenazi, B., Soomro, M. H., Vineis, P., Snieder, H., Bouchard, L., Jaddoe, V. W., Sorensen, T. I. A., Vrijheid, M., Arshad, S. H., Holloway, J. W., Haberg, S. E., Magnus, P., Dwyer, T., Binder, E. B., DeMeo, D. L., Vonk, J. M., Newnham, J., Tantisira, K. G., Kull, I., Wiemels, J. L., Heude, B., Sunyer, J., Nystad, W., Munthe-Kaas, M. C., Raikkonen, K., Oken, E., Huang, R.-C., Weiss, S. T., Anto, J. M., Bousquet, J., Kumar, A., Soderhall, C., Almqvist, C., Cardenas, A., Gruzieva, O., Xu, C.-J., Reese, S. E., Kere, J., Brodin, P., Solomon, O., Wielscher, M., Holland, N., Ghantous, A., Hivert, M.-F., Felix, J. F., Koppelman, G. H., London, S. J. & Melen, E., 2-mrt.-2020, In: Genome medicine. 12, 1, blz. 25 17 blz., 25.

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