Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
- 1 - 50 van 66 resultaten
Zoekresultaten
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2024
Adaptive immunity of type VI CRISPR-Cas systems associated with reverse transcriptase-Cas1 fusion proteins
Molina-Sánchez, M. D., Martínez-Abarca, F., Millán, V., Mestre, M. R., Stehantsev, P., Stetsenko, A., Guskov, A. & Toro, N., dec.-2024, In: Nucleic Acids Research. 52, 22, blz. 14229-14243 15 blz., gkae1154.Onderzoeksoutput › Academic › peer review
Open AccessBestand -
A subgroup of light-driven sodium pumps with an additional Schiff base counterion
Podoliak, E., Lamm, G. H. U., Marin, E., Schellbach, A. V., Fedotov, D. A., Stetsenko, A., Asido, M., Maliar, N., Bourenkov, G., Balandin, T., Baeken, C., Astashkin, R., Schneider, T. R., Bateman, A., Wachtveitl, J., Schapiro, I., Busskamp, V., Guskov, A., Gordeliy, V. & Alekseev, A. & 1 anderen, , 10-apr.-2024, In: Nature Communications. 15, 16 blz., 3119.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand6 Citaten (Scopus)32 Downloads (Pure) -
Blobs form during the single-file transport of proteins across nanopores
Sauciuc, A., Whittaker, J., Tadema, M., Tych, K., Guskov, A. & Maglia, G., 12-sep.-2024, In: Proceedings of the National Academy of Sciences. 121, 38, 10 blz., e2405018121.Onderzoeksoutput › Academic › peer review
Open AccessBestand2 Citaten (Scopus)22 Downloads (Pure) -
Cobalamin decyanation by the membrane transporter BtuM
Martínez Felices, J. M., Barreto, Y. B., Thangaratnarajah, C., Whittaker, J. J., Alencar, A. M., Guskov, A. & Slotboom, D. J., 8-aug.-2024, In: Structure. 32, 13 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand8 Downloads (Pure) -
Custom Design of a Humidifier Chamber for In Meso Crystallization
Marin, E., Kovalev, K., Poelman, T., Veenstra, R., Borshchevskiy, V. & Guskov, A., 3-jan.-2024, In: Crystal Growth & Design. 24, 1, blz. 325-330 6 blz., 3c01034.Onderzoeksoutput › Academic › peer review
Open AccessBestand88 Downloads (Pure) -
Exploring the Ligand Binding and Conformational Dynamics of the Substrate-Binding Domain 1 of the ABC Transporter GlnPQ
Nemchinova, M., Schuurman-Wolters, G. K., Whittaker, J. J., Arkhipova, V., Marrink, S. J., Poolman, B. & Guskov, A., aug.-2024, In: The Journal of Physical Chemistry B. 128, 32, blz. 7822-7832 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand36 Downloads (Pure) -
High Affinity Inhibitors of the Macrophage Infectivity Potentiator Protein from Trypanosoma cruzi, Burkholderia pseudomallei, and Legionella pneumophila: A Comparison
Lohr, T., Herbst, C., Bzdyl, N. M., Jenkins, C., Scheuplein, N. J., Sugiarto, W. O., Whittaker, J. J., Guskov, A., Norville, I., Hellmich, U. A., Hausch, F., Sarkar-Tyson, M., Sotriffer, C. & Holzgrabe, U., 11-okt.-2024, In: ACS Infectious Diseases. 10, 10, blz. 3681–3691 11 blz.Onderzoeksoutput › Academic › peer review
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Regression-Based Active Learning for Accessible Acceleration of Ultra-Large Library Docking
Marin, E., Kovaleva, M., Kadukova, M., Mustafin, K., Khorn, P., Rogachev, A., Mishin, A., Guskov, A. & Borshchevskiy, V., 8-apr.-2024, In: Journal of chemical information and modeling. 64, 7, blz. 2612–2623 12 blz., 3c01661.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand5 Citaten (Scopus)56 Downloads (Pure) -
Unravelled proteins form blobs during translocation across nanopores
Sauciuc, A., Whittaker, J., Tadema, M., Tych, K., Guskov, A. & Maglia, G., 25-jan.-2024, (Submitted) In: bioRxiv. 11 blz.Onderzoeksoutput › Academic
Bestand83 Downloads (Pure) -
2023
Biochemical and structural insight into the chemical resistance and cofactor specificity of the formate dehydrogenase from Starkeya novella
Partipilo, M., Whittaker, J. J., Pontillo, N., Coenradij, J., Herrmann, A., Guskov, A. & Slotboom, D. J., sep.-2023, In: The FEBS Journal. 290, 17, blz. 4238-4255 18 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand2 Citaten (Scopus)71 Downloads (Pure) -
Legionella pneumophila macrophage infectivity potentiator protein appendage domains modulate protein dynamics and inhibitor binding
Wiedemann, C., Whittaker, J. J., Carrillo, V. H. P., Goretzki, B., Dajka, M., Tebbe, F., Harder, J.-M., Krajczy, P. R., Joseph, B., Hausch, F., Guskov, A. & Hellmich, U. A., 1-dec.-2023, In: International Journal of Biological Macromolecules. 252, 15 blz., 126366.Onderzoeksoutput › Academic › peer review
Open AccessBestand1 Citaat (Scopus)71 Downloads (Pure) -
Mutation in glutamate transporter homologue GltTk provides insights into pathologic mechanism of episodic ataxia 6
Colucci, E., Anshari, Z., Patiño-Ruiz, M., Nemchinova, M., Whittaker, J., Slotboom, D. & Guskov, A., 31-mrt.-2023, In: Nature Communications. 14, 10 blz., 1799.Onderzoeksoutput › Academic › peer review
Open AccessBestand4 Citaten (Scopus)88 Downloads (Pure) -
Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Kolosova , O., Zgadzay, Y., Stetsenko, A., Atamas, A., Wu, C.-H., Sachs, M. S., Jenner, L., Guskov, A. & Yusupov, M., dec.-2023, In: Biopolymers and Cell. 39, 4, blz. 265-276 12 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand99 Downloads (Pure) -
Structural Study of the Candida auris Ribosome
Atamas, A. A., Guskov, A. I. & Rogachev, A. V., dec.-2023, In: Moscow University Biological Sciences Bulletin. 78, Suppl 1, blz. S56-S58 3 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand1 Citaat (Scopus)27 Downloads (Pure) -
Yet Another Similarity between Mitochondrial and Bacterial Ribosomal Small Subunit Biogenesis Obtained by Structural Characterization of RbfA from S. aureus
Bikmullin, A. G., Fatkhullin, B., Stetsenko, A., Gabdulkhakov, A., Garaeva, N., Nurullina, L., Klochkova, E., Golubev, A., Khusainov, I., Trachtmann, N., Blokhin, D., Guskov, A., Validov, S., Usachev, K. & Yusupov, M., 20-jan.-2023, In: International Journal of Molecular Sciences. 24, 3, 15 blz., 24032118.Onderzoeksoutput › Academic › peer review
Open AccessBestand4 Citaten (Scopus)107 Downloads (Pure) -
2022
Cryo-EM structure of a tetrameric photosystem I from Chroococcidiopsis TS-821, a thermophilic, unicellular, non-heterocyst-forming cyanobacterium
Semchonok, D. A., Mondal, J., Cooper, C. J., Schlum, K., Li, M., Amin, M., Sorzano, C. O. S., Ramírez-Aportela, E., Kastritis, P. L., Boekema, E. J., Guskov, A. & Bruce, B. D., 10-jan.-2022, In: Plant Communications. 3, 1, 18 blz., 100248.Onderzoeksoutput › Academic › peer review
Open AccessBestand12 Citaten (Scopus)141 Downloads (Pure) -
Crystal Structure of 4,6-α-Glucanotransferase GtfC-ΔC from Thermophilic Geobacillus 12AMOR1: Starch Transglycosylation in Non-Permuted GH70 Enzymes
Pijning, T., Te Poele, E. M., de Leeuw, T. C., Guskov, A. & Dijkhuizen, L., 7-dec.-2022, In: Journal of Agricultural and Food Chemistry. 70, 48, blz. 15283–15295 13 blz., 2c06394.Onderzoeksoutput › Academic › peer review
Open AccessBestand2 Citaten (Scopus)83 Downloads (Pure) -
Crystal Structure of Levansucrase from the Gram-Negative Bacterium Brenneria Provides Insights into Its Product Size Specificity
Xu, W., Ni, D., Hou, X., Pijning, T., Guskov, A., Rao, Y. & Mu, W., 27-apr.-2022, In: Journal of Agricultural and Food Chemistry. 70, 16, blz. 5095-5105 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand12 Citaten (Scopus)160 Downloads (Pure) -
E-site drug specificity of the human pathogen Candida albicans ribosome
Zgadzay, Y., Kolosova , O., Stetsenko, A., Wu, C., Bruchlen, D., Usachev, K., Validov, S., Jenner, L., Rogachev, A., Yusupova, G., Sachs, M. S., Guskov, A. & Yusupov, M., 25-mei-2022, In: Science Advances. 8, 21, 7 blz., eabn1062.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand9 Citaten (Scopus)95 Downloads (Pure) -
2021
A structural view onto disease-linked mutations in the human neutral amino acid exchanger ASCT1
Stehantsev, P., Stetsenko, A., Nemchinova, M., Aduri, N. G., Marrink, S., Gati, C. & Guskov, A., okt.-2021, In: Computational and Structural Biotechnology Journal. 19, blz. 5246-5254 9 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand12 Citaten (Scopus)121 Downloads (Pure) -
Asymmetric CorA Gating Mechanism as Observed by Molecular Dynamics Simulations
Nemchinova, M., Melcr, J., Wassenaar, T., Marrink, S. & Guskov, A., jun.-2021, In: Journal of chemical information and modeling. 61, 5, blz. 2407-2417 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand10 Citaten (Scopus)164 Downloads (Pure) -
Kinetic mechanism of Na+-coupled aspartate transport catalyzed by GltTk
Trinco, G., Arkhipova, V., Garaeva, A., Hutter, C. A. J., Seeger, M. A., Guskov, A. & Slotboom, D., 17-jun.-2021, In: Communications biology. 4, 11 blz., 751.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand9 Citaten (Scopus)84 Downloads (Pure) -
Structural and biochemical characterization of a novel ZntB (CmaX) transporter protein from Pseudomonas aeruginosa
Stetsenko, A., Stehantsev, P., Dranenko, N. O., Gelfand, M. S. & Guskov, A., 1-aug.-2021, In: International Journal of Biological Macromolecules. 184, blz. 760-767 8 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand8 Citaten (Scopus)173 Downloads (Pure) -
Structural and biophysical characterization of the tandem substrate-binding domains of the ABC importer GlnPQ
Plötz, E., Schuurman-Wolters, G., Zijlstra, N., Jager, A., Griffith, D., Guskov, A., Gouridis, G., Poolman, B. & Cordes, T., 7-apr.-2021, In: Open Biology. 11, 4, 16 blz., 200406.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand5 Citaten (Scopus)138 Downloads (Pure) -
Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue
Arkhipova, V., Fu, H., Hoorens, M., Trinco, G., Lameijer, L., Marin, E., Feringa, B. L., Poelarends, G., Szymanski, W., Slotboom, D. & Guskov, A., mrt.-2021, In: Journal of the American Chemical Society. 143, 3, blz. 1513-1520 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand26 Citaten (Scopus)159 Downloads (Pure) -
2020
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds
Rempel, S., Gati, C., Nijland, M., Thangaratnarajah, C., Karyolaimos, A., Gier, J.-W. L. D., Guskov, A. & Slotboom, D., 16-apr.-2020, In: Nature. 580, 7803, blz. 409-412 4 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand68 Citaten (Scopus)233 Downloads (Pure) -
Cation permeability in CorA family of proteins
Stetsenko, A. & Guskov, A., 1-dec.-2020, In: Scientific Reports. 10, 1, 9 blz., 840.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand10 Citaten (Scopus)181 Downloads (Pure) -
Census of halide-binding sites in protein structures
Skitchenko, R. K., Usoltsev, D., Uspenskaya, M., Kajava, A. V. & Guskov, A., 15-mei-2020, In: Bioinformatics (Oxford, England). 36, 10, blz. 3064-3071 8 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand16 Citaten (Scopus)152 Downloads (Pure) -
In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters
Setyawati, I., Stanek, W. K., Dosz-Majsnerowska, M., Ziel-Swier, L., Pardon, E., Steyaert, J., Guskov, A. & Slotboom, D., 22-dec.-2020, In: eLife. 9, blz. 1-21 21 blz., e64389.Onderzoeksoutput › Academic › peer review
Open AccessBestand15 Citaten (Scopus)99 Downloads (Pure) -
Membrane mediated toppling mechanism of the folate energy coupling factor transporter
Faustino, I., Abdizadeh, H., Souza, P. C. T., Jeucken, A., Stanek, W. K., Guskov, A., Slotboom, D. & Marrink, S., 1-dec.-2020, In: Nature Communications. 11, 1, 10 blz., 1763.Onderzoeksoutput › Academic › peer review
Open AccessBestand20 Citaten (Scopus)201 Downloads (Pure) -
Molecular insight into a new low affinity xylan binding module from the xylanolytic gut symbiont Roseburia intestinalis
Leth, M. L., Ejby, M., Madland, E., Kitaoku, Y., Slotboom, D. J., Guskov, A., Aachmann, F. L. & Abou Hachem, M., 1-mei-2020, In: The FEBS Journal. 287, 10, blz. 2105-2117 13 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand9 Citaten (Scopus)109 Downloads (Pure) -
Structural and Functional Characterization of NadR from Lactococcus lactis
Stetsenko, A., Singh, R., Jähme, M., Guskov, A. & Slotboom, D., 22-apr.-2020, In: Molecules. 25, 8, 14 blz., 1940.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand4 Citaten (Scopus)126 Downloads (Pure) -
Structural ensemble of a glutamate transporter homologue in lipid nanodisc environment
Arkhipova, V., Guskov, A. & Slotboom, D., 21-feb.-2020, In: Nature Communications. 11, 1, 9 blz., 998.Onderzoeksoutput › Academic › peer review
Open AccessBestand48 Citaten (Scopus)178 Downloads (Pure) -
2019
A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2
Garaeva, A. A., Guskov, A., Slotboom, D. J. & Paulino, C., 31-jul.-2019, In: Nature Communications. 10, 8 blz., 3427.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand68 Citaten (Scopus)328 Downloads (Pure) -
Binding and transport of D-aspartate by the glutamate transporter homologue GltTk
Arkhipova, V. I., Trinco, G., Thijs, E., Jensen, S., Slotboom, D. & Guskov, A., 1-mei-2019, In: eLife. 8, 12 blz., e45286.Onderzoeksoutput › Academic › peer review
Open AccessBestand20 Citaten (Scopus)361 Downloads (Pure) -
Two binding proteins of the ABC transporter that confers growth of Bifidobacterium animalis subsp. lactis ATCC27673 on β-mannan possess distinct manno-oligosaccharide binding profiles
Ejby, M., Guskov, A., Pichler, M. J., Zanten, G. C., Schoof, E., Saburi, W., Slotboom, D. J. & Abou Hachem, M., jul.-2019, In: Molecular Microbiology. 112, 1, blz. 114-130 17 blz., 14257.Onderzoeksoutput › Academic › peer review
Open AccessBestand23 Citaten (Scopus)156 Downloads (Pure) -
2018
Cryo-EM structure of the human neutral amino acid transporter ASCT2
Garaeva, A., Oostergetel, G., Gati, C., Guskov, A., Batista Paulino, C. & Slotboom, D., 5-jun.-2018, In: Nature Structural & Molecular Biology. 25, blz. 515-521 7 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand106 Citaten (Scopus)189 Downloads (Pure) -
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
Rempel, S., Colucci, E., Gier, J.-W. D., Guskov, A. & Slotboom, D., 2-aug.-2018, In: Nature Communications. 9, 1, 8 blz., 3038.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand29 Citaten (Scopus)394 Downloads (Pure) -
Functional and structural characterization of an ECF-type ABC transporter for vitamin B12
Luís da Silva Santos Guimarães, J. A., Rempel, S., Mous, S. T. M., Tambascia Pereira, C., ter Beek, J., Gier, J.-W. D., Guskov, A. & Slotboom, D., 2018, In: eLife. 7, 16 blz., e35828.Onderzoeksoutput › Academic › peer review
Open AccessBestand35 Citaten (Scopus)379 Downloads (Pure) -
2017
A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy
Franken, L., Oostergetel, G., Pijning, T., Puri, P., Arkhipova, V. I., Boekema, E., Poolman, B. & Guskov, A., 28-sep.-2017, In: Nature Communications. 8, 11 blz., 722.Onderzoeksoutput › Academic › peer review
Open AccessBestand46 Citaten (Scopus)461 Downloads (Pure) -
Analysis of the quality of crystallographic data and the limitations of structural models
Arkhipova, V. I., Guskov, A. & Slotboom, D., dec.-2017, In: The Journal of General Physiology. 149, 12, 13 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand13 Citaten (Scopus)499 Downloads (Pure) -
An Overview of the Top Ten Detergents Used for Membrane Protein Crystallization
Stetsenko, A. & Guskov, A., 1-jul.-2017, In: Crystals. 7, 7, blz. 1-16 16 blz., 197.Onderzoeksoutput › Academic › peer review
Open AccessBestand100 Citaten (Scopus)13615 Downloads (Pure) -
The structural basis of proton driven zinc transport by ZntB
Gati, C., Stetsenko, A., Slotboom, D., Scheres, S. & Guskov, A., 3-nov.-2017, In: Nature Communications. 8, 8 blz., 1313.Onderzoeksoutput › Academic › peer review
Open AccessBestand27 Citaten (Scopus)377 Downloads (Pure) -
2016
Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk
Guskov, A., Jensen, S., Faustino, I., Marrink, S. J. & Slotboom, D. J., 2016, In: Nature Communications. 7, blz. 1-6 6 blz., 13420.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand76 Citaten (Scopus)411 Downloads (Pure) -
Pnu Transporters: Ain't They SWEET?
Jähme, M., Guskov, A. & Slotboom, D. J., feb.-2016, In: Trends in Biochemical Sciences. 41, 2, blz. 117-118 2 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand4 Citaten (Scopus)85 Downloads (Pure) -
Structural insight in the toppling mechanism of an energy-coupling factor transporter
Swier, L. J. Y. M., Guskov, A. & Slotboom, D. J., 30-mrt.-2016, In: Nature Communications. 7, blz. 1-11 12 blz., 11072.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand47 Citaten (Scopus)433 Downloads (Pure) -
2015
Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine
Swier, L. J. Y. M., Monjas, L., Guskov, A., de Voogd, A. R., Erkens, G. B., Slotboom, D. J. & Hirsch, A. K. H., 23-mrt.-2015, In: ChemBioChem. 16, 5, blz. 819-826 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand24 Citaten (Scopus)60 Downloads (Pure) -
The twisted relation between Pnu and SWEET transporters
Jähme, M., Guskov, A. & Slotboom, D., apr.-2015, In: Trends in Biochemical Sciences. 40, 4, blz. 183-188 6 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand14 Citaten (Scopus)69 Downloads (Pure) -
2014
Crystal structure of the vitamin B3 transporter PnuC, a full-length SWEET homolog
Jähme, M., Guskov, A. & Slotboom, D. J., 7-okt.-2014, In: Nature Structural & Molecular Biology. 21, 11, blz. 1013-1015 3 blz.Onderzoeksoutput › Academic › peer review
36 Citaten (Scopus) -
Structural diversity of ABC transporters
ter Beek, J., Guskov, A. & Slotboom, D. J., apr.-2014, In: Journal of general physiology. 143, 4, blz. 419-435 17 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand298 Citaten (Scopus)665 Downloads (Pure)