Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Persoonlijk profiel
Speerpunten
My research interest focuses on the research of molecular mechanisms underlying cerebrovascular diseases, aging processes, and neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. I investigated the role of statins and various natural products, including linalool, as potential neuroprotective agents in neurodegenerative diseases. Lately, my focus has shifted towards delving into mitochondrial metabolism and its link to inflammation in the context of neurodegenerative diseases, particularly the generation and characterization of human microglia derived from induced pluripotent stem cells of Parkinson's disease patients. I am greatly interested in expanding my research in understanding neuroinflammation as a key factor in neurodegenerative diseases.
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
-
Mitochondrial transplantation rescues neuronal cells from ferroptosis
Chen, T., Majerníková, N., Marmolejo-Garza, A., Trombetta-Lima, M., Sabogal-Guáqueta, A. M., Zhang, Y., Ten Kate, R., Zuidema, M., Mulder, P. P. M. F. A., den Dunnen, W., Gosens, R., Verpoorte, E., Culmsee, C., Eisel, U. L. M. & Dolga, A. M., 1-nov.-2023, In: Free Radical Biology and Medicine. 208, blz. 62-72 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand23 Downloads (Pure) -
Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction
Sabogal-Guáqueta, A. M., Marmolejo-Garza, A., Trombetta-Lima, M., Oun, A., Hunneman, J., Chen, T., Koistinaho, J., Lehtonen, S., Kortholt, A., Wolters, J. C., Bakker, B. M., Eggen, B. J. L., Boddeke, E. & Dolga, A., 13-okt.-2023, In: Nature Communications. 14, 1, 24 blz., 6454.Onderzoeksoutput › Academic › peer review
Open AccessBestand5 Downloads (Pure) -
The importance of microglia in metabolic changes in the brain: A world to explore
Sabogal Guaqueta, A., 2023.Onderzoeksoutput › Academic
-
Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies
Goldsteen, P., Sabogal Guaqueta, A., Mulder, P., Bos, I. S. T., Eggens, M., van der Koog, L., Soeiro, J. T., Halayko, A. J., Mathwig, K., Kistemaker, L., Verpoorte, E., Dolga, A. & Gosens, R., 28-okt.-2022, In: Frontiers in Pharmacology. 13, 16 blz., 991072.Onderzoeksoutput › Academic › peer review
Open AccessBestand3 Citaten (Scopus)74 Downloads (Pure) -
Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity
Musheshe, N., Oun, A., Sabogal-Guáqueta, A. M., Trombetta-Lima, M., Mitchel, S. C., Adzemovic, A., Speek, O., Morra, F., van der Veen, C. H. J. T., Lezoualc'h, F., Cheng, X., Schmidt, M. & Dolga, A. M., 4-feb.-2022, In: Antioxidants (Basel, Switzerland). 11, 2, 20 blz., 314.Onderzoeksoutput › Academic › peer review
Open AccessBestand9 Citaten (Scopus)57 Downloads (Pure)