Anika Nagelkerke

Zoekresultaten

• 2023

  3D Culture of human lung fibroblasts decreases proliferative and increases extracellular matrix remodeling genes

  Migulina, N., de Hilster, R. H. J., Bartel, S., Vedder, R. H. J., van den Berge, M., Nagelkerke, A., Timens, W., Harmsen, M. C., Hylkema, M. N., Brandsma, C-A. & Burgess, J. K., 13-nov.-2023, (E-pub ahead of print) In: American Journal of Physiology - Cell Physiology. 32 blz.

  Onderzoeksoutput: Article › Academic › peer review

• A Comparison of Cellular Uptake Mechanisms, Delivery Efficacy, and Intracellular Fate between Liposomes and Extracellular Vesicles

  Gandek, T., van der Koog, L. & Nagelkerke, A., 6-okt.-2023, In: Advanced healthcare materials. 12, 25, 33 blz., 2300319.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  1 Citaat (Scopus)

  2 Downloads (Pure)

• Placenta-on-a-Chip as an In Vitro Approach to Evaluate the Physiological and Structural Characteristics of the Human Placental Barrier upon Drug Exposure: A Systematic Review

  Elzinga, F. A., Khalili, B., Touw, D. J., Prins, J. R., Olinga, P., Leuvenink, H. G. D., van Goor, H., Gordijn, S. J., Nagelkerke, A. & Mian, P., 27-jun.-2023, In: Journal of Clinical Medicine. 12, 13, 20 blz., 4315.

  Onderzoeksoutput › peer review

  Open Access

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  16 Downloads (Pure)

• Polystyrene lung-on-a-chip model for oxygen metabolism studies

  de Haan, P., Mulder, J-P., Karsten, R., Ahmed, M., Pijnenburg, M., Nagelkerke, A., Heijink, I. & Verpoorte, E., 17-okt.-2023, blz. 3112. 2 blz.

  Onderzoeksoutput › Academic
• 2022

  Breaking through the barrier: Modelling and exploiting the physical microenvironment to enhance drug transport and efficacy

  Gładysz, M. Z., Stevanoska, M., Włodarczyk-Biegun, M. K. & Nagelkerke, A., mei-2022, In: Advanced Drug Delivery Reviews. 184, 20 blz., 114183.

  Onderzoeksoutput › peer review

  Open Access

  Bestand
  4 Citaten (Scopus)

  42 Downloads (Pure)

• Development of an ex vivo model for non-alcoholic fatty liver disease using precision-cut liver slices

  Li, M., de Meijer, V., Olinga, P., Nagelkerke, A. & Geng, Y., jul.-2022, In: Journal of Hepatology. 77, blz. S711-S711 1 blz.

  Onderzoeksoutput › Academic

• Extracellular vesicles and soluble factors secreted by lung fibroblasts support alveolar organoid formation

  van der Koog, L., Nagelkerke, A. & Gosens, R., 9-mei-2022, In: European Respiratory Journal. 8, Suppl. 8, 2

  Onderzoeksoutput › Academic

• Liposomes and Extracellular Vesicles as Drug Delivery Systems: A Comparison of Composition, Pharmacokinetics, and Functionalization

  van der Koog, L., Gandek, T. B. & Nagelkerke, A., 2-mrt.-2022, In: Advanced healthcare materials. 11, 5, 32 blz., e2100639.

  Onderzoeksoutput › peer review

  Open Access

  Bestand
  121 Citaten (Scopus)

  174 Downloads (Pure)

• THIN MELT-ELECTROWRITTEN SCAFFOLDS AS A NOVEL ALTERNATIVE FOR POROUS INSERTS IN BLOOD-BRAIN BARRIER MODELS IN VITRO

  Gladysz, M., Kamperman, M., Nagelkerke, A. & Wlodarczyk-Biegun, M., 1-apr.-2022, blz. S486.

  Onderzoeksoutput › Academic
• 2021

  Current developments in modelling the tumour microenvironment in vitro: Incorporation of biochemical and physical gradients

  Ahmed, M. A. M. & Nagelkerke, A., nov.-2021, In: Organs-on-a-Chip. 3, 100012.

  Onderzoeksoutput › peer review

  Open Access

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  117 Downloads (Pure)

• Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities

  Nagelkerke, A., Ojansivu, M., van der Koog, L., Whittaker, T. E., Cunnane, E. M., Silva, A. M., Dekker, N. & Stevens, M. M., aug.-2021, In: Advanced Drug Delivery Reviews. 175, 113775.

  Onderzoeksoutput › peer review

  Open Access

  Bestand
  68 Citaten (Scopus)

  463 Downloads (Pure)

• High-Throughput Molecular Imaging via Deep-Learning-Enabled Raman Spectroscopy

  Horgan, C. C., Jensen, M., Nagelkerke, A., St-Pierre, J-P., Vercauteren, T., Stevens, M. M. & Bergholt, M. S., 7-dec.-2021, In: Analytical Chemistry. 93, 48, blz. 15850-15860 11 blz.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

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  25 Citaten (Scopus)

  122 Downloads (Pure)

• IL-1β mediated nanoscale surface clustering of integrin α5β1 regulates the adhesion of mesenchymal stem cells

  Maynard, S. A., Pchelintseva, E., Zwi-Dantsis, L., Nagelkerke, A., Gopal, S., Korchev, Y. E., Shevchuk, A. & Stevens, M. M., 2021, In: Scientific Reports. 11, 1, 14 blz., 6890 .

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  1 Citaat (Scopus)

  17 Downloads (Pure)

• Image-guided Raman spectroscopy probe-tracking for tumor margin delineation

  Horgan, C. C., Bergholt, M. S., Thin, M. Z., Nagelkerke, A., Kennedy, R., Kalber, T. L., Stuckey, D. J. & Stevens, M. M., mrt.-2021, In: Journal of Biomedical Optics. 26, 3, 15 blz., 036002.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  10 Citaten (Scopus)

  33 Downloads (Pure)

• Improving Breast Cancer Treatment Specificity Using Aptamers Obtained by 3D Cell-SELEX

  Nelissen, F. H. T., Peeters, W. J. M., Roelofs, T. P., Nagelkerke, A., Span, P. N. & Heus, H. A., 9-apr.-2021, In: Pharmaceuticals. 14, 4, 349.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  14 Citaten (Scopus)

  64 Downloads (Pure)

• Integrated photodynamic Raman theranostic system for cancer diagnosis, treatment, and post-treatment molecular monitoring

  Horgan, C., Bergholt, M., Nagelkerke, A., Thin, M. Z., Pence, I., Kauscher, U., Kalber, T., Stuckey, D. & Stevens, M., 2021, In: Theranostics. 11, 4, blz. 2006–2019

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  11 Citaten (Scopus)

  16 Downloads (Pure)

• Multiplexing physical stimulation on single human induced pluripotent stem cell-derived cardiomyocytes for phenotype modulation

  Kit-Anan, W., Mazo, M. M., Wang, B. X., Leonardo, V., Pence, I. J., Gopal, S., Gelmi, A., Nagelkerke, A., Becce, M., Chiappini, C., Harding, S. E., Terracciano, C. M. & Stevens, M. M., 2021, In: Biofabrication. 13, 2, 025004.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access
  11 Citaten (Scopus)

  3 Downloads (Pure)

• Single Particle Automated Raman Trapping Analysis of Breast Cancer Cell-Derived Extracellular Vesicles as Cancer Biomarkers

  Penders, J., Nagelkerke, A., Cunnane, E. M., Pedersen, S. V., Pence, I. J., Coombes, R. C. & Stevens, M. M., 23-nov.-2021, In: Acs Nano. 15, 11, blz. 18192–18205 14 blz.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  41 Citaten (Scopus)

  74 Downloads (Pure)

• The gastrointestinal microbiota in colorectal cancer cell migration and invasion

  Henstra, C., van Praagh, J., Olinga, P. & Nagelkerke, A., 2021, In: Clinical & Experimental Metastasis. 38, blz. 495–510

  Onderzoeksoutput › peer review

  Open Access

  Bestand
  10 Citaten (Scopus)

  209 Downloads (Pure)
• 2020

  Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles

  Whittaker, T. E., Nagelkerke, A., Nele, V., Kauscher, U. & Stevens, M. M., 26-aug.-2020, In: Journal of Extracellular Vesicles. 9, 1, blz. 1807674

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  47 Citaten (Scopus)

  26 Downloads (Pure)

• Gold Nanocluster Extracellular Vesicle Supraparticles: Self-Assembled Nanostructures for Three-Dimensional Uptake Visualization

  Kauscher, U., Penders, J., Nagelkerke, A., Holme, M. N., Nele, V., Massi, L., Gopal, S., Whittaker, T. E. & Stevens, M. M., 14-apr.-2020, In: Langmuir. 36, 14, blz. 3912-3923 12 blz.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  10 Citaten (Scopus)

  286 Downloads (Pure)

• Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling

  Horgan, C. C., Nagelkerke, A., Whittaker, T. E., Nele, V., Massi, L., Kauscher, U., Penders, J., Bergholt, M. S., Hood, S. R. & Stevens, M. M., 2020, In: Journal of materials chemistry b. 8, 20, blz. 4447-4459 13 blz.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  16 Citaten (Scopus)

  49 Downloads (Pure)

• Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting

  Kim, N., Thomas, M. R., Bergholt, M. S., Pence, I. J., Seong, H., Charchar, P., Todorova, N., Nagelkerke, A., Belessiotis-Richards, A., Payne, D. J., Gelmi, A., Yarovsky, I. & Stevens, M. M., 10-jan.-2020, In: Nature Communications. 11, 1, blz. 1-12 207.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  87 Citaten (Scopus)

  25 Downloads (Pure)

• Tunable Hybrid Matrices Drive Epithelial Morphogenesis and YAP Translocation

  Zhang, Y., Zegers, M., Nagelkerke, A., Rowan, A., Span, P. & Kouwer, P., 2020, In: Advanced science . 8, 2

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  11 Citaten (Scopus)

  21 Downloads (Pure)
• 2018

  Interferon-Stimulated Genes Are Involved in Cross-resistance to Radiotherapy in Tamoxifen-Resistant Breast Cancer

  Post, A. E. M., Smid, M., Nagelkerke, A., Martens, J. W. M., Bussink, J., Sweep, F. C. G. J. & Span, P. N., 15-jul.-2018, In: Clinical Cancer Research. 24, 14, blz. 3397-3408 12 blz.

  Onderzoeksoutput › Academic › peer review
  62 Citaten (Scopus)

• Single Particle Automated Raman Trapping Analysis

  Penders, J., Pence, I. J., Horgan, C. C., Bergholt, M. S., Wood, C. S., Najer, A., Kauscher, U., Nagelkerke, A. & Stevens, M. M., 15-okt.-2018, In: Nature Communications. 9, 1, 4256.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  35 Citaten (Scopus)

  26 Downloads (Pure)
• 2016

  Staining Against Phospho-H2AX (γ-H2AX) as a Marker for DNA Damage and Genomic Instability in Cancer Tissues and Cells

  Nagelkerke, A. & Span, P. N., 22-jun.-2016, In: Advances in experimental medicine and biology. 899, blz. 1-10 10 blz.

  Onderzoeksoutput: Article › Academic › peer review
  50 Citaten (Scopus)
• 2015

  Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma

  Nagelkerke, A., Sweep, F. C. G. J., Stegeman, H., Grénman, R., Kaanders, J. H. A. M., Bussink, J. & Span, P. N., jun.-2015, In: Head and Neck: Journal of the Sciences and Specialties of the Head and Neck. 37, 6, blz. 896-905 10 blz.

  Onderzoeksoutput: Article › Academic › peer review
  25 Citaten (Scopus)

• Poor prognosis of constitutive γ-H2AX expressing triple-negative breast cancers is associated with telomere length

  Nagelkerke, A., van Kuijk, S. J. A., Martens, J. W. M., Sweep, F. C. G. J., Hoogerbrugge, N., Bussink, J. & Span, P. N., 2015, In: Biomarkers in medicine. 9, 4, blz. 383-90 8 blz.

  Onderzoeksoutput: Article › Academic › peer review
  14 Citaten (Scopus)

• The mechanical microenvironment in cancer: How physics affects tumours

  Nagelkerke, A., Bussink, J., Rowan, A. E. & Span, P. N., dec.-2015, In: Seminars in cancer biology. 35, blz. 62-70 9 blz.

  Onderzoeksoutput › peer review
  99 Citaten (Scopus)

• Therapeutic targeting of autophagy in cancer. Part I: molecular pathways controlling autophagy

  Nagelkerke, A., Sweep, F. C. G. J., Geurts-Moespot, A., Bussink, J. & Span, P. N., apr.-2015, In: Seminars in cancer biology. 31, blz. 89-98 10 blz.

  Onderzoeksoutput › peer review
  45 Citaten (Scopus)

• Therapeutic targeting of autophagy in cancer. Part II: Pharmacological modulation of treatment-induced autophagy

  Nagelkerke, A., Bussink, J., Geurts-Moespot, A., Sweep, F. C. G. J. & Span, P. N., apr.-2015, In: Seminars in cancer biology. 31, blz. 99-105 7 blz.

  Onderzoeksoutput › peer review
  64 Citaten (Scopus)
• 2014

  LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy

  Nagelkerke, A., Sieuwerts, A. M., Bussink, J., Sweep, F. C. G. J., Look, M. P., Foekens, J. A., Martens, J. W. M. & Span, P. N., feb.-2014, In: Endocrine-Related cancer. 21, 1, blz. 101-12 12 blz.

  Onderzoeksoutput: Article › Academic › peer review
  73 Citaten (Scopus)

• The unfolded protein response as a target for cancer therapy

  Nagelkerke, A., Bussink, J., Sweep, F. C. G. J. & Span, P. N., dec.-2014, In: Biochimica et biophysica acta. 1846, 2, blz. 277-84 8 blz.

  Onderzoeksoutput › peer review
  86 Citaten (Scopus)
• 2013

  Generation of multicellular tumor spheroids of breast cancer cells: How to go three-dimensional

  Nagelkerke, A., Bussink, J., Sweep, F. C. G. J. & Span, P. N., 1-jun.-2013, In: Analytical Biochemistry. 437, 1, blz. 17-9 3 blz.

  Onderzoeksoutput: Article › Academic › peer review
  53 Citaten (Scopus)

• Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response

  Nagelkerke, A., Bussink, J., Mujcic, H., Wouters, B. G., Lehmann, S., Sweep, F. C. G. J. & Span, P. N., 7-jan.-2013, In: Breast cancer research. 15, 1, R2.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

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  168 Citaten (Scopus)

  11 Downloads (Pure)

• Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3

  Mujcic, H., Nagelkerke, A., Rouschop, K. M. A., Chung, S., Chaudary, N., Span, P. N., Clarke, B., Milosevic, M., Sykes, J., Hill, R. P., Koritzinsky, M. & Wouters, B. G., 15-nov.-2013, In: Clinical Cancer Research. 19, 22, blz. 6126-6137 12 blz.

  Onderzoeksoutput › Academic › peer review
  97 Citaten (Scopus)

• The PERK/ATF4/LAMP3-arm of the unfolded protein response affects radioresistance by interfering with the DNA damage response

  Nagelkerke, A., Bussink, J., van der Kogel, A. J., Sweep, F. C. G. J. & Span, P. N., sep.-2013, In: Radiotherapy and Oncology. 108, 3, blz. 415-21 7 blz.

  Onderzoeksoutput: Article › Academic › peer review
  77 Citaten (Scopus)
• 2012

  Kinetics and thiol requirements of iodothyronine 5'-deiodination are tissue-specific in common carp (Cyprinus carpio L.)

  Klaren, P. H. M., Geven, E. J. W., Nagelkerke, A. & Flik, G., 2012, In: Comparative biochemistry and physiology b-Biochemistry & molecular biology. 161, 3, blz. 275-82 8 blz.

  Onderzoeksoutput: Article › Academic › peer review
  8 Citaten (Scopus)
• 2011

  Constitutive expression of γ-H2AX has prognostic relevance in triple negative breast cancer

  Nagelkerke, A., van Kuijk, S. J. A., Sweep, F. C. G. J., Nagtegaal, I. D., Hoogerbrugge, N., Martens, J. W. M., Timmermans, M. A., van Laarhoven, H. W. M., Bussink, J. & Span, P. N., 2011, In: Radiotherapy and Oncology. 101, 1, blz. 39-45 7 blz.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand
  68 Citaten (Scopus)

  9 Downloads (Pure)

• Hypoxic regulation and prognostic value of LAMP3 expression in breast cancer

  Nagelkerke, A., Mujcic, H., Bussink, J., Wouters, B. G., van Laarhoven, H. W. M., Sweep, F. C. G. J. & Span, P. N., 15-aug.-2011, In: Cancer. 117, 16, blz. 3670-81 12 blz.

  Onderzoeksoutput: Article › Academic › peer review
  56 Citaten (Scopus)
• 2010

  18S is an appropriate housekeeping gene for in vitro hypoxia experiments

  Nagelkerke, A., Mujcic, H., Wouters, B. & Span, P. N., 10-aug.-2010, In: British Journal of Cancer. 103, 4, blz. 590; author reply 591-2

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  14 Citaten (Scopus)

  11 Downloads (Pure)