Annechien Plat

2024

B cells critical for outcome in high grade serous ovarian carcinoma

Vledder, A., Paijens, S. T., Loiero, D., Maagdenberg, A., Duiker, E. W., Bart, J., Hendriks, A. M., Jalving, M., Werner, N., van Rooij, N., Plat, A., Wisman, G. B. A., Yigit, R., Roelofsen, T., Kruse, A. J., de Lange, N. M., Koelzer, V. H., de Bruyn, M. & Nijman, H. W., 15-dec.-2024, In: International Journal of Cancer. 155, 12, blz. 2265-2276 12 blz.

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19 Downloads (Pure)

Immune predictors of response to immune checkpoint inhibitors in mismatch repair-deficient endometrial cancer

Grau Bejar, J. F., Yaniz Galende, E., Zeng, Q., Genestie, C., Rouleau, E., de Bruyn, M., Klein, C., Le Formal, A., Edmond, E., Moreau, M., Plat, A., Gouy, S., Maulard, A., Pautier, P., Michels, J., Oaknin, A., Colomba-Blameble, E. & Leary, A., 1-jul.-2024, In: Journal for immunotherapy of cancer. 12, 7, 15 blz., e009143.

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1 Citaat (Scopus)

Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study

Eerkens, A. L., Brummel, K., Vledder, A., Paijens, S. T., Requesens, M., Loiero, D., van Rooij, N., Plat, A., Haan, F.-J., Klok, P., Yigit, R., Roelofsen, T., de Lange, N. M., Klomp, R., Church, D., Ter Elst, A., Wardenaar, R., Spierings, D., Foijer, F. & Koelzer, V. H. & 6 anderen, Bosse, T., Bart, J., Jalving, M., Reyners, A. K. L., de Bruyn, M. & Nijman, H. W., dec.-2024, In: Nature Communications. 15, 17 blz., 7695.

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1 Citaat (Scopus)

36 Downloads (Pure)

2023

Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors

Ważyńska, M. A., Butera, R., Requesens, M., Plat, A., Zarganes-Tzitzikas, T., Neochoritis, C. G., Plewka, J., Skalniak, L., Kocik-Krol, J., Musielak, B., Magiera-Mularz, K., Rodriguez, I., Blok, S. N., de Bruyn, M., Nijman, H. W., Elsinga, P. H., Holak, T. A. & Dömling, A., 27-jul.-2023, In: Journal of Medicinal Chemistry. 66, 14, blz. 9577-9591 15 blz.

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8 Citaten (Scopus)

92 Downloads (Pure)

Development of [⁸⁹Zr]Zr-hCD103.Fab01A and [⁶⁸Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET

Fan, X., Ważyńska, M. A., Kol, A., Perujo Holland, N., Fernandes, B., van Duijnhoven, S. M. J., Plat, A., van Eenennaam, H., Elsinga, P. H., Nijman, H. W. & de Bruyn, M., 20-nov.-2023, In: EJNMMI Research. 13, 1, 11 blz., 100.

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54 Downloads (Pure)

2022

Development of 89 Zr-anti-CD103 PET imaging for non-invasive assessment of cancer reactive T cell infiltration

Kol, A., Fan, X., Wazynska, M. A., Van Duijnhoven, S. M. J., Giesen, D., Plat, A., Van Eenennaam, H., Elsinga, P. H., Nijman, H. W. & De Bruyn, M., 5-dec.-2022, In: Journal for immunotherapy of cancer. 10, 12, 32 blz., e004877.

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2 Citaten (Scopus)

49 Downloads (Pure)

Expression of CD39 Identifies Activated Intratumoral CD8+T Cells in Mismatch Repair Deficient Endometrial Cancer

Lubbers, J. M., Ważyńska, M. A., van Rooij, N., Kol, A., Workel, H. H., Plat, A., Paijens, S. T., Vlaming, M. R., Spierings, D. C. J., Elsinga, P. H., Bremer, E., Nijman, H. W. & de Bruyn, M., 11-apr.-2022, In: Cancers. 14, 8, 13 blz., 1924.

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4 Citaten (Scopus)

167 Downloads (Pure)

Tumor infiltrating CD8/CD103/TIM-3-expressing lymphocytes in epithelial ovarian cancer co-express CXCL13 and associate with improved survival

Vlaming, M., Bilemjian, V., Freile, J. Á., Melo, V., Plat, A., Huls, G., Nijman, H., de Bruyn, M. & Bremer, E., 21-okt.-2022, In: Frontiers in Immunology. 13, 11 blz., 1031746.

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5 Citaten (Scopus)

113 Downloads (Pure)

2021

Association of homozygous variants of STING1 with outcome in human cervical cancer

Lubbers, J. M., Koopman, B., de Klerk-Sluis, J. M., van Rooij, N., Plat, A., Pijper, H., Koopman, T., van Hemel, B. M., Hollema, H., Wisman, B., Nijman, H. W. & de Bruyn, M., jan.-2021, In: Cancer science. 112, 1, blz. 61-71 11 blz.

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8 Citaten (Scopus)

163 Downloads (Pure)

Combined STING levels and CD103+ T cell infiltration have significant prognostic implications for patients with cervical cancer

Kol, A., Lubbers, J. M., Terwindt, A. L. J., Workel, H. H., Plat, A., Wisman, G. B. A., Bart, J., Nijman, H. W. & De Bruyn, M., 12-jun.-2021, In: OncoImmunology. 10, 1, 12 blz., 1936391.

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14 Citaten (Scopus)

91 Downloads (Pure)

Prognostic image-based quantification of CD8CD103 T cell subsets in high-grade serous ovarian cancer patients

Paijens, S. T., Vledder, A., Loiero, D., Duiker, E. W., Bart, J., Hendriks, A. M., Jalving, M., Workel, H. H., Hollema, H., Werner, N., Plat, A., Wisman, G. B. A., Yigit, R., Arts, H., Kruse, A. J., de Lange, N. M., Koelzer, V. H., de Bruyn, M. & Nijman, H. W., 6-jun.-2021, In: OncoImmunology. 10, 1, 11 blz., 1935104.

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13 Citaten (Scopus)

108 Downloads (Pure)

2020

Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome

Merkus-Brunekreeft, K., Paijens, S., Wouters, M., Komdeur, F., Eggink, F., Lubbers-Marsman, J., Workel, H., Slikke, van der, E. C., Propper, N. E. J., Leffers, N., Adam, J., Pijper, H., Plat, A., Kol, A., Nijman, H. & Bruyn, de, M., 13-mei-2020, In: OncoImmunology. 9, 1, blz. 1-12 12 blz., 1760705.

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13 Citaten (Scopus)

42 Downloads (Pure)

Prognostic Integrated Image-Based Immune and Molecular Profiling in Early-Stage Endometrial Cancer

Horeweg, N., de Bruyn, M., Nout, R. A., Stelloo, E., Kedzierska, K. Z., León-Castillo, A., Plat, A., Mertz, K. D., Osse, M., Jürgenliemk-Schulz, I. M., Lutgens, L. C., Jobsen, J. J., van der Steen-Banasik, E. M., Smit, V. T. H. B. M., Creutzberg, C. L., Bosse, T., Nijman, H. W., Koelzer, V. H. & Church, D. N., 1-dec.-2020, In: Cancer immunology research. 8, 12, blz. 1508-1519 12 blz.

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48 Citaten (Scopus)

152 Downloads (Pure)

Transcriptional Activity and Stability of CD39+CD103+CD8+T Cells in Human High-Grade Endometrial Cancer

Workel, H. H., van Rooij, N., Plat, A., Spierings, D. C. J., Fehrmann, R. S. N., Nijman, H. W. & de Bruyn, M., jun.-2020, In: International Journal of Molecular Sciences. 21, 11, 18 blz., 3770.

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10 Citaten (Scopus)

166 Downloads (Pure)

2019

A transcriptionally distinct CXCL13+CD103+CD8+ T-cell population is associated with B-cell recruitment and neoantigen load in human cancer

Workel, H. H., Lubbers, J. M., Arnold, R., Prins, T. M., van der Vlies, P., de Lange, K., Bosse, T., Van Gool, I. C., Eggink, F. A., Wouters, M. C., Komdeur, F. L., van der Slikke, E. C., Creutzberg, C. L., Kol, A., Plat, A., Glaire, M., Church, D. N., Nijman, H. W. & de Bruyn, M., mei-2019, In: Cancer immunology research. 7, 5, blz. 784-796 13 blz.

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154 Citaten (Scopus)

601 Downloads (Pure)

2018

L1CAM expression in uterine carcinosarcoma is limited to the epithelial component and may be involved in epithelial-mesenchymal transition

Versluis, M., Plat, A., de Bruyn, M., Matias-Guiu, X., Trovic, J., Krakstad, C., Nijman, H. W., Bosse, T., de Bock, G. H. & Hollema, H., nov.-2018, In: Virchows Archiv : an International Journal of Pathology. 473, 5, blz. 591-598 8 blz.

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9 Citaten (Scopus)

331 Downloads (Pure)

2017

CD103+tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+T cells associated with prognostic benefit and therapy response in cervical cancer

Komdeur, F. L., Prins, T. M., van de Wall, S., Plat, A., Wisman, G. B. A., Hollema, H., Daemen, T., Church, D. N., De Bruyn, M. & Nijman, H. W., 2017, In: OncoImmunology. 6, 9, 14 blz., 1338230.

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127 Citaten (Scopus)

503 Downloads (Pure)

Mutagenesis of nisin's leader peptide proline strongly modulates export of precursor nisin

Plat, A., Kuipers, A., Crabb, J., Rink, R. & Moll, G. N., mrt.-2017, In: Antonie Van Leeuwenhoek: International Journal of General and Molecular Microbiology. 110, 3, blz. 321-330 10 blz.

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4 Citaten (Scopus)

108 Downloads (Pure)

The prognostic benefit of tumour-infiltrating Natural Killer cells in endometrial cancer is dependent on concurrent overexpression of Human Leucocyte Antigen-E in the tumour microenvironment

Versluis, M. A. C., Marchal, S., Plat, A., de Bock, G. H., van Hall, T., de Bruyn, M., Hollema, H. & Nijman, H. W., nov.-2017, In: European Journal of Cancer. 86, blz. 285-295 11 blz.

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27 Citaten (Scopus)

51 Downloads (Pure)

2016

CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy

Komdeur, F. L., Wouters, M. C. A., Workel, H. H., Tijans, A. M., Terwindt, A. L. J., Brunekreeft, K. L., Plat, A., Klip, H. G., Eggink, F. A., Leffers, N., Helfrich, W., Samplonius, D. F., Bremer, E., Wisman, G. B. A., Daemen, T., Duiker, E. W., Hollema, H., Nijman, H. W. & de Bruyn, M., 15-nov.-2016, In: Oncotarget. 7, 46, blz. 75130-75144 15 blz.

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62 Citaten (Scopus)

281 Downloads (Pure)

CD103 defines intraepithelial CD8+ PD1+ tumour-infiltrating lymphocytes of prognostic significance in endometrial adenocarcinoma

Workel, H. H., Komdeur, F. L., Wouters, M. C. A., Plat, A., Klip, H. G., Eggink, F. A., Wisman, G. B. A., Arts, H. J. G., Oonk, M. H. M., Mourits, M. J. E., Yigit, R., Versluis, M., Duiker, E. W., Hollema, H., de Bruyn, M. & Nijman, H. W., jun.-2016, In: European Journal of Cancer. 60, blz. 1-11 11 blz.

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116 Citaten (Scopus)

32 Downloads (Pure)

Discovery, production and modification of 5 novel lantibiotics using the promiscuous nisin modification machinery

van Heel, A. J., Kloosterman, T. G., Montalban-Lopez, M., Deng, J., Plat, A., Baudu, B., Hendriks, D., Moll, G. N. & Kuipers, O. P., 13-jun.-2016, In: ACS Synthetic Biology. 5, 10, blz. 1146-1154 9 blz., 6b00033.

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71 Citaten (Scopus)

144 Downloads (Pure)

Microsatellite instability derived JAK1 frameshift mutations are associated with tumor immune evasion in endometrioid endometrial cancer

Stelloo, E., Versluis, M. A., Nijman, H. W., de Bruyn, M., Plat, A., Osse, E. M., van Dijk, R. H., Nout, R. A., Creutzberg, C. L., de Bock, G. H., Smit, V. T., Bosse, T. & Hollema, H., 28-jun.-2016, In: Oncotarget. 7, 26, blz. 39885-39893 9 blz.

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32 Citaten (Scopus)

275 Downloads (Pure)

Treatment Regimen, Surgical Outcome, and T-cell Differentiation Influence Prognostic Benefit of Tumor-Infiltrating Lymphocytes in High-Grade Serous Ovarian Cancer

Wouters, M. C. A., Komdeur, F. L., Workel, H. H., Klip, H. G., Plat, A., Kooi, N. M., Wisman, G. B. A., Mourits, M. J. E., Arts, H. J. G., Oonk, M. H. M., Yigit, R., de Jong, S., Melief, C. J. M., Hollema, H., Duiker, E. W., Daemen, T., de Bruyn, M. & Nijman, H. W., 1-feb.-2016, In: Clinical Cancer Research. 22, 3, blz. 714-724 11 blz.

Onderzoeksoutput: Article › Academic › peer review

57 Citaten (Scopus)

2015

Prediction model for regional or distant recurrence in endometrial cancer based on classical pathological and immunological parameters

Versluis, M. A., de Jong, R. A., Plat, A., Bosse, T., Smit, V. T., Mackay, H., Powell, M., Leary, A., Mileshkin, L., Kitchener, H. C., Crosbie, E. J., Edmondson, R. J., Creutzberg, C. L., Hollema, H., Daemen, T., de Bock, G. H. & Nijman, H. W., 1-sep.-2015, In: British Jounal of Cancer. 113, 5, blz. 786-793 8 blz.

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21 Citaten (Scopus)

270 Downloads (Pure)

The major myelin-resident protein PLP is transported to myelin membranes via a transcytotic mechanism: involvement of sulfatide

Baron, W., Ozgen, H., Klunder, B., de Jonge, J. C., Nomden, A., Plat, A., Trifilieff, E., de Vries, H. & Hoekstra, D., jan.-2015, In: Molecular and Cellular Biology. 35, 1, blz. 288-302 15 blz.

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25 Citaten (Scopus)

106 Downloads (Pure)

2004

Potential interaction between acenocoumarol and diclofenac, naproxen and ibuprofen and role of CYP2C9 genotype

van Dijk, K., Plat, A., van Dijk, A., Piersma-Wichers, M., de Vries-Bots, A., Slomp, J., de Jong van den Berg, L. & Brouwers, J., jan.-2004, In: Thrombosis and Haemostasis. 91, 1, blz. 95-101 7 blz.

Onderzoeksoutput › Academic › peer review

39 Citaten (Scopus)

Annechien Plat, MSc

Onderzoeksoutput

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