Persoonlijk profiel
Speerpunten
I am a hematopathologist at the University Medical Center Groningen and a principal investigator in the SALL (stem cells, aging, leukemia and lymphoma) program of the CRCG (Cancer Research Center Groningen). My main research interest involves malignant lymphoma, in particular Hodgkin lymphoma, with a strong focus on interactions between tumor cells and the microenvironment. In my PhD thesis "Classical Hodgkin lymphoma: population based studies on HLA and EBV (2007)" and follow-up studies, I discovered that the HLA system is intricately involved in Hodgkin lymphoma susceptibility, pathogenesis and prognosis and published these findings in the Lancet, Journal of Clinical Oncology and Blood. I secured three Dutch Cancer Society grants to do functional follow-up studies on these findings. Fruitful international collaborations involve the Interlymph consortium on genome wide association studies, the Lymphoma group of the EORTC and various groups in the UK, Canada and the US. My areas of expertise are: immunology, tumor cell biology, association studies and molecular diagnostics in pathology.
Expertise gerelateerd aan duurzame ontwikkelingsdoelstellingen van de VN
In 2015 stemden de VN-lidstaten in met 17 wereldwijde duurzame ontwikkelingsdoelstellingen (Sustainable Development Goals, SDG's) om armoede te beëindigen, de planeet te beschermen en voor iedereen welvaart te garanderen. Het werk van deze persoon draagt bij aan de volgende duurzame ontwikkelingsdoelstelling(en):
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SDG 2 – Geen honger
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SDG 3 – Goede gezondheid en welzijn
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
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Dynamics of circulating tumour DNA in relapsed/refractory diffuse large B-cell lymphoma patients
Zhong, Y., Bult, J., Veltmaat, N., de Jesus, F. M., Sillje, L., Kluiver, J., van den Berg, A., Plattel, W., Diepstra, A. & Nijland, M., mrt.-2026, In: British Journal of Haematology. 208, 3, blz. 874-882 9 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand19 Downloads (Pure) -
Intra-erythrocyte creatine, plasma creatine and long-term outcomes in stable kidney transplant recipients: Results from the TransplantLines Biobank and Cohort study
TransplantLines Investigators, Doorenbos, C. S. E., Post, A., van der Veen, Y., Franssen, C. F. M., Eisenga, M. F., Dullaart, R. P. F., Navis, G., Wu, Q., Gonzalez-Delgado, J. M., Connelly, M. A. & Bakker, S. J. L., feb.-2026, In: Clinical Nutrition Open Science. 65, 17 blz., 100606.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand1 Downloads (Pure) -
Overlapping macrophage immune profiles in polymyalgia rheumatica and giant cell arteritis
Zhang, A., Jiemy, W. F., van Sleen, Y., Xu, S., Sandovici, M., Abdulahad, W. H., Diepstra, A., Hein, S., Graver, J. C., Heeringa, P., Dasgupta, B., Brouwer, E. & van der Geest, K. S. M., feb.-2026, In: Rheumatology (Oxford, England). 65, 2, 6 blz., keaf629.Onderzoeksoutput: Article › Academic › peer review
1 Citaat (Scopus) -
Symptom Burden and Patient-Reported Outcomes in Kidney Transplant Recipients: Results From the TransplantLines Biobank and Cohort Studies
TransplantLines Investigators, Riemersma, N. L., Knobbe, T. J., Kremer, D., Nolte, S., Bültmann, U., Annema, C., Shehab, N. B. N., Eisenga, M. F., Berger, S. P., Bakker, S. J. L. & Nieuwenhuijs, G. J., jan.-2026, In: Kidney Medicine. 8, 1, 11 blz., 101168.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand2 Downloads (Pure) -
Atezolizumab Consolidation in Patients with High Risk Diffuse Large B-cell Lymphoma in Complete Remission after R-CHOP
Nijland, M., Issa, D. E., Bult, J. A. A., Deeren, D., Velders, G. A., Nijziel, M. R., Sandberg, Y., Vergote, V. K., Oosterveld, M., Fijnheer, R., Brouwer, R., Boersma, R., Wu, K., Nieuwenhuizen, L., Vermaat, J. S., van Kampen, R. J. W., Terpstra, W. E., Snauwaert, S., van der Poel, M. W. & de Jongh, E. & 22 anderen, , 10-jul.-2025, In: Blood Advances. 9, 14, blz. 3530–3539 10 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand4 Citaten (Scopus)26 Downloads (Pure)
Activiteiten
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TOX as a novel biomarker in T cell large granular lymphocytic leukemia
Diepstra, A. (Speaker)
23-jan.-2025Activiteit: Academic presentation › Academic
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A unifying pathogenetic framework for classic Hodgkin lymphoma
Diepstra, A. (Speaker)
6-feb.-2025Activiteit: Academic presentation › Academic
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Moleculaire tumor board hematologie
Diepstra, A. (Speaker)
27-nov.-2024Activiteit: Academic presentation › Academic
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European Masters in Molecular Pathology
Diepstra, A. (Organiser)
17-jun.-2024 → 20-jun.-2024Activiteit: Organising and contributing to an event › Academic
Datasets
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Supplementary Material for: MicroRNA High Throughput Loss-of-Function Screening Reveals an Oncogenic Role for miR-21-5p in Hodgkin Lymphoma
Niu, F. (Contributor), Yuan, Y. (Contributor), Sarkis Azkanaz, M. (Contributor), Diepstra, A. (Contributor), Bystrykh, L. (Contributor), Visser, L. (Contributor), Dzikiewicz-Krawczyk, A. (Contributor), Osinga, J. (Contributor), Rutgers, B. (Contributor), Kok, K. (Contributor), Koerts, J. (Contributor), Terpstra, M. (Contributor), Kluiver, J. (Contributor), van den Berg, A. (Contributor), Nolte, I. M. (Contributor) & de Jong, D. (Contributor), figshare Academic Research System, 5-sep.-2018
DOI: 10.6084/m9.figshare.7047695.v1
Dataset
Knipsels
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Whodunit? Het speurwerk van de patholoog bij lymfeklierkanker
07/08/2024
1 item van Media-aandacht
Pers / media: Expert Comment › Popular
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Serum TARC Levels Increased Years Prior to Hodgkin Lymphoma Diagnosis
16/01/2024
1 Mediabijdrage
Pers / media: Onderzoek › Academic
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Serumspiegels TARC-eiwit al jaren voor diagnose Hodgkin lymfoom verhoogd
01/12/2023
1 Mediabijdrage
Pers / media: Onderzoek › Professional
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Hodgkin lymphoma can be diagnosed much earlier
19/10/2023
1 item van Media-aandacht
Pers / media: Onderzoek › Academic
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Video Interview for the Video Journal of Haematological Oncology on TARC in Hodgkin lymphoma
26/10/2022
1 Mediabijdrage
Pers / media: Expert Comment › Academic
Prijzen
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Appointment Coordinating Committee Member International Interlymph Consortium
Diepstra, A. (Recipient), 24-nov.-2022
Prijs: Appointment › Academic
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Expert in Lymphoma
Diepstra, A. (Recipient), 8-dec.-2021
Prijs: National/international honour › Academic
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Translational research Transplant-BRAVE trial
Diepstra, A. (Recipient), 2020
Prijs: National/international honour › Academic
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