Noheda’s research focuses on understanding the relationship between structure and functionality of thin films of ferroelectric, piezoelectric and multiferroic materials, the control of nano-domains that self-assemble by strain engineering, as well as the characterization of the distinct properties of domain walls. Her main scientific contributions have been the discovery of low symmetry (monoclinic) phases in high piezoelectric materials (PZT and MPB piezoelectrics) and the observation of domain walls as "vertical interfaces" with distinct structure and functionalities.  Although her research is fundamental in nature, it is inspired by two main application areas that she believes will enable the next technological revolution: piezoelectric energy harvesting for low power electronics and the development of novel materials for neuromorphic computing.