Cancan Qi

2025

Association of exposure to second-hand smoke during childhood with blood DNA methylation

Pregnancy And Childhood Epigenetics (PACE) Consortium, Cosin-Tomas, M., Hoang, T., Qi, C., Monasso, G. S., Langdon, R., Kebede Merid, S., Calas, L., de Prado-Bert, P., Richmond, R., Jaddoe, V. V., Duijts, L., Wright, J., Annesi-Maesano, I., Grazuleviciene, R., Karachaliou, M., Koppelman, G. H., Melén, E., Gruzieva, O. & Vrijheid, M. & 4 anderen, Yousefi, P., Felix, J. F., London, S. J. & Bustamante, M., jan.-2025, In: Environment international. 195, 10 blz., 109204.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

Genome-Wide Association Study Reveals a Causal Relationship Between Allergic Rhinitis and Hazelnut Allergy

Sun, Y., Vonk, J. M., Kersten, E. T. G., Qi, C., Sprikkelman, A. B. & Koppelman, G. H., 2025, In: Allergy. 80, 1, blz. 309-318 10 blz.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

2023

Asthma susceptibility: learning from genetic diversity

Sun, Y., Kersten, E. T. G., Qi, C. & Koppelman, G. H., apr.-2023, In: Journal of Allergy and Clinical Immunology. 151, 4, blz. 904-906 3 blz.

Onderzoeksoutput: Editorial › Academic › peer review

Open Access

Bestand

2 Citaten (Scopus)

63 Downloads (Pure)

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

23andMe Research Team, Budu-Aggrey, A., Kilanowski, A., Sobczyk, M. K., Shringarpure, S. S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B. M., Thomas, L. F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J. V. T., Bork-Jensen, J. & Marenholz, I. & 33 anderen, Arnau-Soler, A., Jeong, A., Fawcett, K. A., Baurecht, H., Rodriguez, E., Alves, A. C., Kumar, A., Sleiman, P. M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C.-J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C. A., Thiering, E., Wu, B., Kress, S., Kothalawala, D. M., Kadalayil, L., Duan, J., Zhang, H., Hadebe, S., Hoffmann, T., Jorgenson, E., Choquet, H., Vonk, J. M., Weiss, S. T., Standl, M. & Paternoster, L., 4-okt.-2023, In: Nature Communications. 14, 18 blz., 6172.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

36 Citaten (Scopus)

59 Downloads (Pure)

Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohn’s disease: a multi-omics Mendelian randomization study

Xu, S., Li, X., Zhang, S., Qi, C., Zhang, Z., Ma, R., Xiang, L., Chen, L., Zhu, Y., Tang, C., Bourgonje, A. R., Li, M., He, Y., Zeng, Z., Hu, S., Feng, R. & Chen, M., 11-mei-2023, In: BMC Medicine. 21, 16 blz., 179.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

63 Citaten (Scopus)

99 Downloads (Pure)

2022

Cell-type eQTL deconvolution of bronchial epithelium through integration of single-cell and bulk RNA-seq

Qi, C., Berg, M., Chu, X., Timens, W., Kole, T., van den Berge, M., Xu, C. J., Koppelman, G. H., Nawijn, M. C. & Li, Y., dec.-2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 12, blz. 3663-3666 4 blz.

Onderzoeksoutput: Letter › Academic › peer review

Open Access

Bestand

177 Downloads (Pure)

Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways

U-BIOPRED study group, Cambridge Lung Cancer Early Detection Programme, INER-Ciencias Mexican Lung Program, Aliee, H., Massip, F., Qi, C., de Biase, M. S., van Nijnatten, J., Kersten, E. T. G., Kermani, N. Z., Khuder, B., Vonk, J. M., Vermeulen, R. C. H., Neighbors, M., Tew, G. W., Grimbaldeston, M. A., Ten Hacken, N. H. T., Hu, S., Guo, Y. & Zhang, X. & 17 anderen, Sun, K., Hiemstra, P. S., Ponder, B. A., Mäkelä, M. J., Malmström, K., Rintoul, R. C., Reyfman, P. A., Theis, F. J., Brandsma, C.-A., Adcock, I. M., Timens, W., Xu, C. J., van den Berge, M., Schwarz, R. F., Koppelman, G. H., Nawijn, M. C. & Faiz, A., feb.-2022, In: Allergy. 77, 2, blz. 690-694 5 blz.

Onderzoeksoutput: Letter › Academic › peer review

Open Access

Bestand

18 Citaten (Scopus)

64 Downloads (Pure)

Nasal DNA methylation at three CpG sites predicts childhood allergic disease

van Breugel, M., Qi, C., Xu, Z., Pedersen, C. E. T., Petoukhov, I., Vonk, J. M., Gehring, U., Berg, M., Bügel, M., Carpaij, O. A., Forno, E., Morin, A., Eliasen, A. U., Jiang, Y., van den Berge, M., Nawijn, M. C., Li, Y., Chen, W., Bont, L. J. & Bønnelykke, K. & 3 anderen, Celedón, J. C., Koppelman, G. H. & Xu, C. J., 1-dec.-2022, In: Nature Communications. 13, 1, 13 blz., 7415.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

24 Citaten (Scopus)

109 Downloads (Pure)

Pulmonary Function and Blood DNA Methylation: A Multi-Ancestry Epigenome-Wide Association Meta-Analysis

BIOS consortium, GoDMC, Lee, M., Huan, T., McCartney, D. L., Chittoor, G., de Vries, M., Lahousse, L., Nguyen, J. N., Brody, J. A., Castillo-Fernandez, J., Terzikhan, N., Qi, C., Joehanes, R., Min, J. L., Smilnak, G. J., Shaw, J. R., Yang, C. X., Colicino, E., Hoang, T. T. & Bermingham, M. L. & 32 anderen, Xu, H., Justice, A. E., Xu, C.-J., Rich, S. S., Cox, S. R., Vonk, J. M., Prokić, I., Sotoodehnia, N., Tsai, P.-C., Schwartz, J. D., Leung, J. M., Sikdar, S., Walker, R. M., Harris, S. E., van der Plaat, D. A., Van Den Berg, D. J., Bartz, T. M., Spector, T. D., Vokonas, P. S., Marioni, R. E., Taylor, A. M., Liu, Y., Barr, R. G., Lange, L. A., Baccarelli, A. A., Obeidat, M., Fornage, M., Wang, T., Ward, J. M., Koppelman, G. H., Boezen, H. M. & London, S. J., 1-aug.-2022, In: American Journal of Respiratory and Critical Care Medicine. 206, 3, blz. 321-336 16 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

19 Citaten (Scopus)

75 Downloads (Pure)

2021

A genome-wide association study of severe asthma exacerbations in Latino children and adolescents

Yan, Q., Forno, E., Herrera-Luis, E., Pino-Yanes, M., Qi, C., Rios, R., Han, Y.-Y., Kim, S., Oh, S., Acosta-Pérez, E., Zhang, R., Hu, D., Eng, C., Huntsman, S., Avila, L., Boutaoui, N., Cloutier, M. M., Soto-Quiros, M. E., Xu, C.-J. & Lasky-Su, J. & 9 anderen, Kiedrowski, M. R., Figueiredo, C., Bomberger, J., Barreto, M. L., Canino, G., Chen, W., Koppelman, G. H., Burchard, E. G. & Celedón, J. C., 1-apr.-2021, In: European Respiratory Journal. 57, 4, 10 blz., 2002693.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

17 Citaten (Scopus)

141 Downloads (Pure)

Cell type eQTL deconvolution of bronchial epithelium through integration of single cell and bulk RNA-seq

Qi, C., Berg, M., Chu, X., Van den Berge, M., Xu, C., Koppelman, G., Nawijn, M. & Li, Y., 5-sep.-2021, In: European Respiratory Journal. 58, 2 blz.

Onderzoeksoutput: Meeting Abstract › Academic

Epigenome-Wide DNA Methylation and Pesticide Use in the Agricultural Lung Health Study

BIOS Consortium, Hoang, T. T., Qi, C., Paul, K. C., Lee, M., White, J. D., Richards, M., Auerbach, S. S., Long, S., Shrestha, S., Wang, T., Freeman, L. E. B., Hofmann, J. N., Parks, C., Xu, C.-J., Ritz, B., Koppelman, G. H. & London, S. J., sep.-2021, In: Environmental Health Perspectives. 129, 9, 11 blz., 097008.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

29 Citaten (Scopus)

88 Downloads (Pure)

Exposure to violence, chronic stress, nasal DNA methylation, and atopic asthma in children

Yan, Q., Forno, E., Cardenas, A., Qi, C., Han, Y.-Y., Acosta-Pérez, E., Kim, S., Zhang, R., Boutaoui, N., Canino, G., Vonk, J. M., Xu, C.-J., Chen, W., Marsland, A., Oken, E., Gold, D. R., Koppelman, G. H. & Celedón, J. C., jul.-2021, In: Pediatric pulmonology. 56, 7, blz. 1896-1905 10 blz.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

23 Citaten (Scopus)

236 Downloads (Pure)

Infant RSV immunoprophylaxis changes nasal epithelial DNA methylation at 6 years of age

Xu, C.-J., Scheltema, N. M., Qi, C., Vedder, R., Klein, L. B. C., Nibbelke, E. E., van der Ent, C. K., Bont, L. J. & Koppelman, G. H., dec.-2021, In: Pediatric pulmonology. 56, 12, blz. 3822-3831 10 blz.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

8 Citaten (Scopus)

126 Downloads (Pure)

Multi-omics approaches to understand respiratory disease

Qi, C., 2021, [Groningen]: University of Groningen. 215 blz.

Onderzoeksoutput

Open Access

Bestand

1148 Downloads (Pure)

Predicting childhood allergy using machine learning methods on multi-omics data

van Breugel, M., Qi, C., Jiang, Y., Pedersen, C.-E. T., Pethoukhov, I., Vonk, J., Gehring, U., Berg, M., Bugel, M., Capraij, O., Forno, E., Morin, A., Eliasen, A. U., Xu, Z., Van Den Berge, M., Nawijn, M., Li, Y., Chen, W., Bont, L. & Bonnelykke, K. & 3 anderen, Celedon, J., Koppelman, G. & Xu, C.-J., 5-sep.-2021, In: European Respiratory Journal. 58, 4 blz.

Onderzoeksoutput: Meeting Abstract › Academic

Residential PM2.5 exposure and the nasal methylome in children

Sordillo, J. E., Cardenas, A., Qi, C., Rifas-Shiman, S. L., Coull, B., Luttmann-Gibson, H., Schwartz, J., Kloog, I., Hivert, M.-F., DeMeo, D. L., Baccarelli, A. A., Xu, C.-J., Gehring, U., Vonk, J. M., Koppelman, G., Oken, E. & Gold, D. R., aug.-2021, In: Environment international. 153, 9 blz., 106505.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

12 Citaten (Scopus)

41 Downloads (Pure)

Shared DNA methylation signatures in childhood allergy: The MeDALL study

BIOS Consortium, Xu, C.-J., Gruzieva, O., Qi, C., Esplugues, A., Gehring, U., Bergstroem, A., Mason, D., Chatzi, L., Porta, D., Carlsen, K. C. L., Baiz, N., Madore, A.-M., Alenius, H., van Rijkom, B., Jankipersadsing, S. A., van der Vlies, P., Kull, I., van Hage, M. & Bustamante, M. & 26 anderen, Lertxundi, A., Torrent, M., Santorelli, G., Fantini, M. P., Hovland, V., Pesce, G., Fyhrquist, N., Laatikainen, T., Nawijn, M. C., Li, Y., Wijmenga, C., Netea, M. G., Bousquet, J., Anto, J. M., Laprise, C., Haahtela, T., Annesi-Maesano, I., Carlsen, K.-H., Gori, D., Kogevinas, M., Wright, J., Soederhaell, C., Vonk, J. M., Sunyer, J., Melen, E. & Koppelman, G. H., mrt.-2021, In: Journal of Allergy and Clinical Immunology. 147, 3, blz. 1031-1040 10 blz.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

26 Citaten (Scopus)

60 Downloads (Pure)

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics

NHLBI LungMap Consortium, Human Cell Atlas Lung Biological Network, Muus, C., Luecken, M. D., Eraslan, G., Sikkema, L., Waghray, A., Heimberg, G., Kobayashi, Y., Vaishnav, E. D., Subramanian, A., Smillie, C., Jagadeesh, K. A., Duong, E. T., Fiskin, E., Triglia, E. T., Ansari, M., Cai, P., Lin, B. & Buchanan, J. & 32 anderen, Chen, S., Shu, J., Haber, A. L., Chung, H., Montoro, D. T., Adams, T., Aliee, H., Allon, S. J., Andrusivova, Z., Angelidis, I., Ashenberg, O., Bassler, K., Bécavin, C., Benhar, I., Bergenstråhle, J., Bergenstråhle, L., Bolt, L., Braun, E., Bui, L. T., Callori, S., Chaffin, M., Chichelnitskiy, E., Chiou, J., Conlon, T. M., Cuoco, M. S., Cuomo, A. S. E., Deprez, M., Duclos, G., Fine, D., Fischer, D. S., Hu, Y. & Qi, C., mrt.-2021, In: Nature Medicine. 27, 3, blz. 546-559 14 blz.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

236 Citaten (Scopus)

119 Downloads (Pure)

2020

Determinants of SARS-CoV-2 receptor gene expression in upper and lower airways

Aliee, H., Massip, F., Qi, C., Stella de Biase, M., van Nijnatten, J. L., Kersten, E. T. G., Kermani, N. Z., Khuder, B., Vonk, J. M., Vermeulen, R. C. H., Neighbors, M., Tew, G. W., Grimbaldeston, M., Ten Hacken, N. H. T., Hu, S., Guo, Y., Zhang, X., Sun, K., Hiemstra, P. S. & Ponder, B. A. & 14 anderen, Makela, M. J., Malmstrom, K., Rintoul, R. C., Reyfman, P. A., Theis, F. J., Brandsma, C.-A., Adcock, I., Timens, W., Xu, C. J., van den Berge, M., Schwarz, R. F., Koppelman, G. H., Nawijn, M. C. & Faiz, A., 2-sep.-2020, 40 blz. (medRxiv : the preprint server for health sciences).

Onderzoeksoutput: Voordruk › Academic

Open Access

Bestand

75 Downloads (Pure)

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

Vehmeijer, F. O. L., Kuepers, L. K., Sharp, G. C., Salas, L. A., Lent, S., Jima, D. D., Tindula, G., Reese, S., Qi, C., Gruzieva, O., Page, C., Rezwan, F., Melton, P. E., Nohr, E., Escaramis, G., Rzehak, P., Heiskala, A., Gong, T., Tuominen, S. T. & Gao, L. & 65 anderen, Ross, J. P., Starling, A. P., Holloway, J. W., Yousefi, P., Aasvang, G. M., Beilin, L. J., Bergstrom, A., Binder, E., Chatzi, L., Corpeleijn, E., Czamara, D., Eskenazi, B., Ewart, S., Ferre, N., Grote, V., Gruszfeld, D., Haberg, S. E., Hoyo, C., Huen, K., Karlsson, R., Kull, I., Langhendries, J.-P., Lepeule, J., Magnus, M. C., Maguire, R. L., Molloy, P. L., Monnereau, C., Mori, T. A., Oken, E., Raikkonen, K., Rifas-Shiman, S., Ruiz-Arenas, C., Sebert, S., Ullemar, V., Verduci, E., Vonk, J. M., Xu, C.-J., Yang, I., Zhang, H., Zhang, W., Karmaus, W., Dabelea, D., Muhlhausler, B. S., Breton, C., Lahti, J., Almqvist, C., Jarvelin, M.-R., Koletzko, B., Vrijheid, M., Sorensen, T. I. A., Huang, R.-C., Arshad, S. H., Nystad, W., Melen, E., Koppelman, G. H., London, S. J., Holland, N., Bustamante, M., Murphy, S. K., Hivert, M.-F., Baccarelli, A., Relton, C. L., Snieder, H., Jaddoe, V. W. V. & Felix, J. F., 25-dec.-2020, In: Genome medicine. 12, 1, 15 blz., 105.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

54 Citaten (Scopus)

145 Downloads (Pure)

DNA methylation at five CpG sites of nasal brushings can predict childhood allergic disease

Qi, C., van Breugel, M., Jiang, Y., Petoukhov, I., Vonk, J. M., Gehring, U., Bugel, M., Forno, E., Chen, W., Celedon, C., Koppelman, G. H. & Xu, C., dec.-2020, In: European Journal of Human Genetics. 28, SUPPL 1, blz. 727-728 2 blz.

Onderzoeksoutput › Academic

Epigenome-wide association study identifies DNA methylation markers for asthma remission in whole blood and nasal epithelium

BIOS Consortium, Qi, C., Vonk, J. M., van der Plaat, D. A., Nieuwenhuis, M. A. E., Dijk, F. N., Aïssi, D., Siroux, V., Boezen, H. M., Xu, C.-J. & Koppelman, G. H., 11-dec.-2020, In: Clinical and translational allergy. 10, 1, blz. 60 13 blz., 60.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

12 Citaten (Scopus)

85 Downloads (Pure)

Epigenome-Wide Association Study of DNA Methylation and Adult Asthma in the Agricultural Lung Health Study

Hoang, T. T., Sikdar, S., Xu, C.-J., Lee, M. K., Cardwell, J., Forno, E., Imboden, M., Jeong, A., Madore, A.-M., Qi, C., Wang, T., Bennett, B. D., Ward, J. M., Parks, C. G., Beane-Freeman, L. E., King, D., Motsinger-Reif, A., Umbach, D. M., Wyss, A. B. & Schwartz, D. A. & 7 anderen, Celedón, J. C., Laprise, C., Ober, C., Probst-Hensch, N., Yang, I. V., Koppelman, G. H. & London, S. J., sep.-2020, In: European Respiratory Journal. 56, 3, 14 blz., 2000217.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

45 Citaten (Scopus)

94 Downloads (Pure)

Nasal DNA methylation profiling of asthma and rhinitis

Qi, C., Jiang, Y., Yang, I. V., Forno, E., Wang, T., Vonk, J. M., Gehring, U., Smit, H. A., Milanzi, E. B., Carpaij, O. A., Berg, M., Hesse, L., Brouwer, S., Cardwell, J., Vermeulen, C. J., Acosta-Pérez, E., Canino, G., Boutaoui, N., van den Berge, M. & Teichmann, S. A. & 5 anderen, Nawijn, M. C., Chen, W., Celedón, J. C., Xu, C.-J. & Koppelman, G. H., jun.-2020, In: Journal of Allergy and Clinical Immunology. 145, 6, blz. 1655-1663 9 blz.

Onderzoeksoutput › Academic › peer review

Open Access

Bestand

60 Citaten (Scopus)

89 Downloads (Pure)

Psychosocial Stressors, DNA Methylation in Airway Epithelium, and Asthma in Children

Yan, Q., Cardenas, A., Forno, E., Qi, C., Han, Y., Acosta-Perez, E., Zhang, R., Boutaoui, N., Canino, G., Chen, W., Oken, E., Xu, C., Gold, D. R., Koppelman, G. H. & Celedon, J. C., 2020, In: American Journal of Respiratory and Critical Care Medicine. 201, 2 blz.

Onderzoeksoutput › Academic

2019

A genome-wide study of DNA methylation in nasal epithelium, atopy, and atopic asthma in children

Forno, E., Wang, T., Qi, C., Yan, Q., Xu, C.-J., Boutaoui, N., Han, Y.-Y., Weeks, D. E., Jiang, Y., Rosser, F., Vonk, J. M., Brouwer, S., Acosta-Perez, E., Colón-Semidey, A., Alvarez, M., Canino, G., Koppelman, G. H., Chen, W. & Celedón, J. C., apr.-2019, In: The Lancet. Respiratory Medicine. 7, 4, blz. 336-346 11 blz.

Onderzoeksoutput › Academic › peer review

Open Access

144 Citaten (Scopus)

Epigenome-Wide Association Study Identifies Epigenetic Markers for Asthma and Rhinitis in Nasal Epithelial Cells

Qi, C., Jiang, Y., Yang, I. V., Forno, E., Wang, T., Vonk, J. M., Gehring, U., Cardwell, J., Acosta-Perez, E., Canino, G., Boutaoui, N., Chen, W., Celedon, J. C., Xu, C. & Koppelman, G. H., 2019, In: American Journal of Respiratory and Critical Care Medicine. 199, 2 blz.

Onderzoeksoutput › Academic

Infant RSV infection changes nasal epithelial DNA methylation at 6 years of age

Xu, C., Scheltema, N. M., Qi, C., Vedder, R., Klein, L. B. C., Nibbelke, E. E., Van Der Ent, C. K., Bont, L. J. & Koppelman, G. H., 28-sep.-2019, In: European Respiratory Journal. 54, 2 blz.

Onderzoeksoutput: Meeting Abstract › Academic

Nasal Methylation Panel Accurately Classifies Children by Atopy or Atopic Asthma

Forno, E., Wang, T., Qi, C., Yan, Q., Xu, C., Boutaoui, N., Han, Y., Weeks, D., Jiang, Y., Rosser, F., Vonk, J., Brouwer, S., Acosta-Perez, E., Colon-Semidey, A., Alvarez, M., Canino, G., Koppelman, G. H., Chen, W. & Celedon, J. C., 2019, In: American Journal of Respiratory and Critical Care Medicine. 199, 2 blz.

Onderzoeksoutput › Academic

The role of epigenetics in the development of childhood asthma

Qi, C., Xu, C.-J. & Koppelman, G. H., 2019, In: Expert review of clinical immunology. 15, 12, blz. 1287-1302 16 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

38 Citaten (Scopus)

173 Downloads (Pure)

2018

Epigenomewide Association Study Identifies DNA Methylation Markers for Asthma Remission

Xu, C., van der Plaat, D. A., Qi, C., Boezen, H. M., Vonk, J. M. & Koppelman, G. H., 2018, In: American Journal of Respiratory and Critical Care Medicine. 197, 2 blz.

Onderzoeksoutput › Academic

Cancan Qi

Onderzoeksoutput

Zoekresultaten