Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
- 39 resultaten
Zoekresultaten
-
2024
Genome-wide forward genetic screening to identify receptors and proteins mediating nanoparticle uptake and intracellular processing
Montizaan, D., Bartucci, R., Reker-Smit, C., Weerd, de, S., Åberg, C., Guryev, V., Spierings, D. & Salvati, A., jul.-2024, In: Nature Nanotechnology. 19, blz. 1022-1031 10 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand6 Citaten (Scopus)137 Downloads (Pure) -
2023
Cell surface biotinylation to identify the receptors involved in nanoparticle uptake into endothelial cells
Aliyandi, A., Smit, C. R., Zuhorn, I. S. & Salvati, A., 1-jan.-2023, In: Acta Biomaterialia. 155, blz. 507-520 14 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand8 Citaten (Scopus)131 Downloads (Pure) -
Role of Curvature-Sensing Proteins in the Uptake of Nanoparticles with Different Mechanical Properties
Montizaan, D., Saunders, C., Yang, K., Sasidharan, S., Maity, S., Reker-Smit, C., Stuart, M. C. A., Montis, C., Berti, D., Roos, W. H. & Salvati, A., 27-sep.-2023, In: Small. 19, 39, 13 blz., 2303267.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand3 Citaten (Scopus)84 Downloads (Pure) -
Temperature-responsive and biocompatible nanocarriers based on clay nanotubes for controlled anti-cancer drug release
Hemmatpour, H., Haddadi-Asl, V., Burgers, T. C. Q., Yan, F., Stuart, M. C. A., Reker-Smit, C., Vlijm, R., Salvati, A. & Rudolf, P., 2023, In: Nanoscale. 15, blz. 2402-2416 15 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand16 Citaten (Scopus)71 Downloads (Pure) -
2022
Explaining the polarized macrophage pool during murine allergic lung inflammation
Draijer, C., Florez-Sampedro, L., Reker-Smit, C., Post, E., van Dijk, F. & Melgert, B. N., 20-dec.-2022, In: Frontiers in Immunology. 13, 15 blz., 1056477.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand13 Citaten (Scopus)98 Downloads (Pure) -
Mechanisms of Uptake and Membrane Curvature Generation for the Internalization of Silica Nanoparticles by Cells
Francia, V., Reker-Smit, C. & Salvati, A., 13-apr.-2022, In: Nano Letters. 22, 7, blz. 3118-3124 7 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand19 Citaten (Scopus)182 Downloads (Pure) -
Osteoprotegerin Expression in Liver is Induced by IL13 through TGFβ
Adhyatmika, A., Putri, K. S. S., Gore, E., Mangnus, K. A., Reker-Smit, C., Schuppan, D., Beljaars, L., Olinga, P. & Melgert, B. N., 22-jan.-2022, In: Cellular physiology and biochemistry. 56, 1, blz. 28-38 11 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand4 Citaten (Scopus)206 Downloads (Pure) -
2021
Correlating Corona Composition and Cell Uptake to Identify Proteins Affecting Nanoparticle Entry into Endothelial Cells
Aliyandi, A., Reker-Smit, C., Bron, R., Zuhorn, I. S. & Salvati, A., 13-dec.-2021, In: ACS Biomaterials Science & Engineering. 7, 12, blz. 5573–5584 12 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand30 Citaten (Scopus)169 Downloads (Pure) -
Effects of Protein Source on Liposome Uptake by Cells: Corona Composition and Impact of the Excess Free Proteins
Yang, K., Reker-Smit, C., Stuart, M. C. A. & Salvati, A., 21-jul.-2021, In: Advanced healthcare materials. 10, 14, 12 blz., 2100370.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand20 Citaten (Scopus)167 Downloads (Pure) -
2020
Comparison of the uptake mechanisms of zwitterionic and negatively charged liposomes by HeLa cells
Montizaan, D., Yang, K., Reker-Smit, C. & Salvati, A., nov.-2020, In: Nanomedicine-Nanotechnology biology and medicine. 30, 10 blz., 102300.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand38 Citaten (Scopus)178 Downloads (Pure) -
Osteoprotegerin Is more than a Possible Serum Marker in Liver Fibrosis: A Study into Its Function in Human and Murine Liver
Adhyatmika, A., Beljaars, L., Putri, K. S. S., Habibie, H., Boorsma, C. E., Reker-Smit, C., Luangmonkong, T., Guney, B., Haak, A., Mangnus, K. A., Post, E., Poelstra, K., Ravnskjaer, K., Olinga, P. & Melgert, B. N., mei-2020, In: Pharmaceutics. 12, 5, 21 blz., 471.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand18 Citaten (Scopus)130 Downloads (Pure) -
2019
Corona Composition Can Affect the Mechanisms Cells Use to Internalize Nanoparticles
Francia, V., Yang, K., Deville, S., Reker-Smit, C., Nelissen, I. & Salvati, A., 22-okt.-2019, In: Acs Nano. 13, 10, blz. 11107-11121 15 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand219 Citaten (Scopus)346 Downloads (Pure) -
Limits and challenges in using transport inhibitors to characterize how nano-sized drug carriers enter cells
Francia, V., Reker-Smit, C., Boel, G. & Salvati, A., 1-jun.-2019, In: Nanomedicine. 14, 12, blz. 1533-1549 17 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand50 Citaten (Scopus)406 Downloads (Pure) -
Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats
Klein, S., Frohn, F., Magdaleno, F., Reker-Smit, C., Schierwagen, R., Schierwagen, I., Uschner, F. E., van Dijk, F., Fürst, D. O., Djudjaj, S., Boor, P., Poelstra, K., Beljaars, L. & Trebicka, J., 19-feb.-2019, In: Scientific Reports. 9, 1, blz. 2256Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand28 Citaten (Scopus)283 Downloads (Pure) -
2018
Collagen morphology influences macrophage shape and marker expression in vitro
Vasse, G. F., Kühn, P. T., Zhou, Q., Bhusari, S. A., Reker-Smit, C., Melgert, B. N. & van Rijn, P., mrt.-2018, In: Journal of Immunology and Regenerative Medicine. 1, blz. 13-20 8 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand205 Downloads (Pure) -
2017
Upregulation of Epac-1 in Hepatic Stellate Cells by Prostaglandin E-2 in Liver Fibrosis Is Associated with Reduced Fibrogenesiss
Schippers, M., Beljaars, L., Post, E., Lotersztajn, S., Reker-Smit, C., Han, B., Llancao, P. A., Schmidt, M. & Poelstra, K., 1-nov.-2017, In: Journal of Pharmacology and Experimental Therapeutics. 363, 2, blz. 126-135 10 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand19 Citaten (Scopus)89 Downloads (Pure) -
2016
PGE(2)-treated macrophages inhibit development of allergic lung inflammation in mice
Draijer, C., Boorsma, C. E., Reker-Smit, C., Post, E., Poelstra, K. & Melgert, B. N., jul.-2016, In: Journal of Leukocyte Biology. 100, 1, blz. 95-102 8 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand41 Citaten (Scopus)60 Downloads (Pure) -
2014
Hepatic Localization of Macrophage Phenotypes during Fibrogenesis and Resolution of Fibrosis in Mice and Humans
Beljaars, L., Schippers, M., Reker-Smit, C., Martinez, F. O., Helming, L., Poelstra, K. & Melgert, B. N., 8-sep.-2014, In: Frontiers in Immunology. 5, 11 blz., 430.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand72 Citaten (Scopus)373 Downloads (Pure) -
2013
Enhanced Effectivity of an ALK5-Inhibitor after Cell-Specific Delivery to Hepatic Stellate Cells in Mice with Liver Injury
van Beuge, M. M., Prakash, J., Lacombe, M., Post, E., Reker-Smit, C., Beljaars, L. & Poelstra, K., 18-feb.-2013, In: PLoS ONE. 8, 2, 9 blz., e56442.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand27 Citaten (Scopus)295 Downloads (Pure) -
2011
Increased Liver Uptake and Reduced Hepatic Stellate Cell Activation with a Cell-Specific Conjugate of the Rho-kinase Inhibitor Y27632
van Beuge, M. M., Prakash, J., Lacombe, M., Post, E., Reker-Smit, C., Beljaars, L. & Poelstra, K., aug.-2011, In: Pharmaceutical Research. 28, 8, blz. 2045-2054 10 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand37 Citaten (Scopus)59 Downloads (Pure) -
Intravenous administration of recombinant human IL-10 suppresses the development of anti-thy 1-induced glomerulosclerosis in rats.
Rachmawati, H., Beljaars, L., Reker-Smit, C., Bakker, H., van Loenen - Weemaes, A.-M., Lub-de Hooge, M. & Poelstra, K., 2011, In: Pda journal of pharmaceutical science and technology. 65, 2, blz. 116-130Onderzoeksoutput: Article › Academic › peer review
15 Citaten (Scopus) -
Reduction of Fibrogenesis by Selective Delivery of a Rho Kinase Inhibitor to Hepatic Stellate Cells in Mice
van Beuge, M. M., Prakash, J., Lacombe, M., Gosens, R., Post, E., Reker-Smit, C., Beljaars, L. & Poelstra, K., jun.-2011, In: Journal of Pharmacology and Experimental Therapeutics. 337, 3, blz. 628-635 8 blz.Onderzoeksoutput: Article › Academic › peer review
55 Citaten (Scopus) -
2009
A Study on the Effects of IL-10 in Anti-Thy 1-Induced Glomerulonephritis in Rats
Rachmawati, H., Beljaars, L., Reker-Smit, C., Bakker, H. I., Van Loenen-Weemaes, A. M. & Poelstra, K., 2009, In: International journal of pharmacology. 5, 6, blz. 346-353 8 blz.Onderzoeksoutput: Article › Academic › peer review
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2008
Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic rat livers
Hagens, W. I., Beljaars, L., Mann, D. A., Wright, M. C., Julien, B., Lotersztajn, S., Reker-Smit, C. & Poelstra, K., mrt.-2008, In: Journal of Pharmacology and Experimental Therapeutics. 324, 3, blz. 902-910 9 blz.Onderzoeksoutput: Article › Academic › peer review
45 Citaten (Scopus) -
2007
A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats
Adrian, J. E., Kamps, J. A. A. M., Scherphof, G. L., Meijer, D. K. F., van Loenen-Weemaes, A.-M., Reker-Smit, C., Terpstra, P. & Poelstra, K., jun.-2007, In: Biochimica et Biophysica Acta-Biomembranes. 1768, 6, blz. 1430-1439 10 blz.Onderzoeksoutput: Article › Academic › peer review
43 Citaten (Scopus) -
Chemical modification of interleukin-10 with mannose 6-phosphate groups yields a liver-selective cytokine
Rachmawati, H., Reker-Smit, C., Lub-de Hooge, M., van Loenen - Weemaes, A.-M., Poelstra, K. & Beljaars, L., mei-2007, In: Drug Metabolism and Disposition. 35, 5, blz. 814-821 8 blz.Onderzoeksoutput: Article › Academic › peer review
25 Citaten (Scopus) -
Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats
Adrian, J. E., Poelstra, K., Scherphof, G. L., Meijer, D. K. F., van Loenen - Weemaes, A.-M., Reker-Smit, C., Morselt, H. W. M., Zwiers, P. & Kamps, J. A. A. M., mei-2007, In: Journal of Pharmacology and Experimental Therapeutics. 321, 2, blz. 536-543 8 blz.Onderzoeksoutput: Article › Academic › peer review
48 Citaten (Scopus) -
Local inhibition of liver fibrosis by specific delivery of a platelet-derived growth factor kinase inhibitor to hepatic stellate cells
Gonzalo, T., Beljaars, L., van de Bovenkamp, M., Temming, K., van Loenen, A.-M., Reker-Smit, C., Meijer, D. K. F., Lacombe, M., Opdam, F., Keri, G., Orfi, L., Poelstra, K. & Kok, R. J., jun.-2007, In: Journal of Pharmacology and Experimental Therapeutics. 321, 3, blz. 856-865 10 blz.Onderzoeksoutput: Article › Academic › peer review
71 Citaten (Scopus) -
Pharmacokinetics of a hepatic stellate cell-targeted doxorubicin construct in bile duct-ligated rats
Greupink, R., Reker-Smit, C., Proost, J. H., Weemaes, A.-M. V. L., de Hooge, M., Poelstra, K. & Beljaars, L., 1-mei-2007, In: Biochemical Pharmacology. 73, 9, blz. 1455-1462 8 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand8 Citaten (Scopus)53 Downloads (Pure) -
Targeting 15d-prostaglandin J(2) to hepatic stellate cells: Two options evaluated
Hagens, W. I., Mattos Pinto, A., Greupink, R., de Jager-Krikken, A., Reker-Smit, C., van Loenen - Weemaes, A.-M., Gouw, A. S. H., Poelstra, K. & Beljaars, L., mrt.-2007, In: Pharmaceutical Research. 24, 3, blz. 566-574 9 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand44 Citaten (Scopus)51 Downloads (Pure) -
2006
Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems
Adrian, J. E., Poelstra, K., Scherphof, G., Molema, G., Meijer, D. K. F., Reker-Smit, C., Morselt, H. & Kamps, J., mrt.-2006, In: Journal of Hepatology. 44, 3, blz. 560-567 8 blz.Onderzoeksoutput: Article › Academic › peer review
53 Citaten (Scopus) -
Prediction of the pharmacokinetics of succinylated human serum albumin in man from in vivo disposition data in animals and in vitro liver slice incubations
Proost, J., Beljaars, L., Olinga, P., Swart, P., Kuipers, M., Reker-Smit, C., Groothuis, G. & Meijer, D., feb.-2006, In: European Journal of Pharmaceutical Sciences. 27, 2-3, blz. 123-132 10 blz.Onderzoeksoutput: Article › Academic › peer review
13 Citaten (Scopus) -
Selective targeting of pentoxifylline platinum-based to hepatic stellate cells using a novel linker technology
Gonzalo, T., Talman, E., de Ven, A., Temming, K., Greupink, R., Beljaars, L., Reker-Smit, C., Meijer, D., Molema, G., Poelstra, K. & Kok, R., 10-mrt.-2006, In: Journal of Controlled Release. 111, 1-2, blz. 193-203 11 blz.Onderzoeksoutput: Article › Academic › peer review
53 Citaten (Scopus) -
The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo
Greupink, R., Bakker, H., Bouma, W., Reker-Smit, C., Meijer, D., Beljaars, L. & Poelstra, K., mei-2006, In: Journal of Pharmacology and Experimental Therapeutics. 317, 2, blz. 514-521 8 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand60 Citaten (Scopus)111 Downloads (Pure) -
2005
Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell
Greupink, R., Bakker, H., Reker-Smit, C., van Loenen - Weemaes, A.-M., Kok, R. J., Meijer, D. K. F., Beljaars, L. & Poelstra, K., nov.-2005, In: Journal of Hepatology. 43, 5, blz. 884-892 9 blz.Onderzoeksoutput: Article › Academic › peer review
46 Citaten (Scopus) -
2004
Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo
Beljaars, L., van der Strate, B., Bakker, H., Reker-Smit, C., van Loenen - Weemaes, A.-M., Wiegmans, F. C., Harmsen, M. C., Molema, G. & Meijer, D. K. F., 2004, In: Antiviral Research. 63, 3, blz. 197-208 12 blz.Onderzoeksoutput: Article › Academic › peer review
79 Citaten (Scopus) -
Pharmacokinetic and biodistribution profile of recombinant human interleukin-10 following intravenous administration in rats with extensive liver fibrosis
Rachmawati, H., Beljaars, L., Reker-Smit, C., van Loenen - Weemaes, A.-M., Hagens, W. I., Meijer, D. K. F. & Poelstra, K., nov.-2004, In: Pharmaceutical Research. 21, 11, blz. 2072-2078 7 blz.Onderzoeksoutput: Article › Academic › peer review
33 Citaten (Scopus) -
2002
The antiviral protein human lactoferrin is distributed in the body to cytomegalovirus (CMV) infection-prone cells and tissues
Beljaars, L., Bakker, H. I., van der Strate, B. W. A., Smit, C., Duijvestijn, A. M., Meijer, D. K. F. & Molema, G., jan.-2002, In: Pharmaceutical Research. 19, 1, blz. 54-62 9 blz.Onderzoeksoutput: Article › Academic › peer review
13 Citaten (Scopus) -
The influence of charge clustering on the anti-HIV-1 activity and in vivo distribution of negatively charged albumins
Beljaars, L., Floris, R., Berkhout, B., Smit, C., Meijer, D. K. F. & Molema, G., 1-mei-2002, In: Biochemical Pharmacology. 63, 9, blz. 1663-1673 11 blz., PII S0006-2952(02)00912-7.Onderzoeksoutput: Article › Academic › peer review
6 Citaten (Scopus)