Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Persoonlijk profiel
Speerpunten
Single cell sequencing, genome instability, structural variations, ageing, stem cells, cancer, immunology
Expertise gerelateerd aan duurzame ontwikkelingsdoelstellingen van de VN
In 2015 stemden de VN-lidstaten in met 17 wereldwijde duurzame ontwikkelingsdoelstellingen (Sustainable Development Goals, SDG's) om armoede te beëindigen, de planeet te beschermen en voor iedereen welvaart te garanderen. Het werk van deze persoon draagt bij aan de volgende duurzame ontwikkelingsdoelstelling(en):
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Diana Spierings actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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Single-cell chromosome and bulk transcriptome analysis as a diagnostic tool to differentiate between localized and metastatic pheochromocytoma and sympathetic paraganglioma
Berends, A. M. A., Wardenaar, R., van den Bos, H., Tijhuis, A. E., Links, T. P., Feelders, R. A., Hofland, L. J., Kruijff, S., Pacak, K., Spierings, D. C. J., Kerstens, M. N. & Foijer, F., 3-mei-2025, (E-pub ahead of print) In: Oncogene. 1122.Onderzoeksoutput › Academic › peer review
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CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma
Saba, K. H., Difilippo, V., Styring, E., Nilsson, J., Magnusson, L., van den Bos, H., Wardenaar, R., Spierings, D. C. J., Foijer, F., Nathrath, M., Haglund de Flon, F., Baumhoer, D. & Nord, K. H., 25-sep.-2024, In: npj Genomic Medicine. 9, 1, 12 blz., 42.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand2 Citaten (Scopus)61 Downloads (Pure) -
Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapy
Edwards, F., Fantozzi, G., Simon, A. Y., Morretton, J.-P., Herbette, A., Tijhuis, A. E., Wardenaar, R., Foulane, S., Gemble, S., Spierings, D. C. J., Foijer, F., Mariani, O., Vincent-Salomon, A., Roman-Roman, S., Sastre-Garau, X., Goundiam, O. & Basto, R., 2024, In: PLOS BIOLOGY. 22, 9, 30 blz., e3002759.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand4 Citaten (Scopus)55 Downloads (Pure) -
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression
Molina, O., Ortega-Sabater, C., Thampi, N., Fernández-Fuentes, N., Guerrero-Murillo, M., Martínez-Moreno, A., Vinyoles, M., Velasco-Hernández, T., Bueno, C., Trincado, J. L., Granada, I., Campos, D., Giménez, C., Boer, J. M., den Boer, M. L., Calvo, G. F., Camós, M., Fuster, J. L., Velasco, P. & Ballerini, P. & 6 anderen, , 1-jan.-2024, In: EMBO Molecular Medicine. 16, 1, blz. 64-92 29 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand3 Citaten (Scopus)110 Downloads (Pure) -
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy
Karbon, G., Schuler, F., Braun, V. Z., Eichin, F., Haschka, M., Drach, M., Sotillo, R., Geley, S., Spierings, D. C., Tijhuis, A. E., Foijer, F. & Villunger, A., 28-mei-2024, In: Embo Reports. 25, blz. 2743-2772 30 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand71 Downloads (Pure)
Activiteiten
- 1 Academic presentation
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Dutch Hematology congress
Spierings, D. (Speaker)
24-jan.-2018 → 26-jan.-2018Activiteit: Academic presentation › Academic
Datasets
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Single cell whole genome sequencing of high hyperdiploid acute lymphoblastic leukemia
Woodward, E. (Contributor), Yang, M. (Contributor), Moura-Castro, L. H. (Contributor), van den Bos, H. (Contributor), Gunnarsson, R. (Contributor), Arvidsson, L. O. (Contributor), Spierings, D. C. J. (Contributor), Castor, A. (Contributor), Duployez, N. (Contributor), Zaliova, M. (Contributor), Zuna, J. (Contributor), Johansson, B. (Contributor), Foijer, F. (Contributor) & Paulsson, K. (Contributor), National Bioinformatics Infrastructure Sweden, 22-feb.-2022
DOI: 10.17044/scilifelab.19160954.v1, https://scilifelab.figshare.com/articles/dataset/Single_cell_whole_genome_sequencing_of_high_hyperdiploid_acute_lymphoblastic_leukemia/19160954/1
Dataset
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Additional file 3 of Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses
Shaikh, N. (Contributor), Mazzagatti, A. (Contributor), De Angelis, S. (Contributor), Johnson, S. C. (Contributor), Bakker, B. (Contributor), Spierings, D. (Contributor), Wardenaar, R. (Contributor), Maniati, E. (Contributor), Wang, J. (Contributor), Boemo, M. A. (Contributor), Foijer, F. (Contributor) & McClelland, S. E. (Contributor), figshare Academic Research System, 20-okt.-2022
DOI: 10.6084/m9.figshare.21376242.v1, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Replication_stress_generates_distinctive_landscapes_of_DNA_copy_number_alterations_and_chromosome_scale_losses/21376242/1
Dataset
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Additional file 6: Table S2. of Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies
Bakker, B. (Creator), Taudt, A. (Creator), Belderbos, M. E. (Creator), Porubský, D. (Creator), Spierings, D. C. J. (Creator), de Jong, T. V. (Contributor), Halsema, N. (Creator), Kazemier, H. G. (Creator), Hoekstra-Wakker, K. (Creator), Bradley, A. (Creator), de Bont, E. S. J. M. (Contributor), van den Berg, A. (Contributor), Guryev, V. (Creator), Lansdorp, P. M. (Creator), Colomé-Tatché, M. (Contributor) & Foijer, F. (Creator), figshare, 31-mei-2016
DOI: 10.6084/m9.figshare.c.3601100_d2
Dataset
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Additional file 4: Table S1. of Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies
Bakker, B. (Creator), Taudt, A. (Creator), Belderbos, M. E. (Creator), Porubský, D. (Creator), Spierings, D. C. J. (Creator), de Jong, T. V. (Contributor), Halsema, N. (Creator), Kazemier, H. G. (Creator), Hoekstra-Wakker, K. (Creator), Bradley, A. (Creator), de Bont, E. S. J. M. (Contributor), van den Berg, A. (Contributor), Guryev, V. (Creator), Lansdorp, P. M. (Creator), Colomé-Tatché, M. (Contributor) & Foijer, F. (Creator), figshare, 31-mei-2016
DOI: 10.6084/m9.figshare.c.3601100_d7
Dataset
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Additional file 2 of Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses
Shaikh, N. (Contributor), Mazzagatti, A. (Contributor), De Angelis, S. (Contributor), Johnson, S. C. (Contributor), Bakker, B. (Contributor), Spierings, D. (Contributor), Wardenaar, R. (Contributor), Maniati, E. (Contributor), Wang, J. (Contributor), Boemo, M. A. (Contributor), Foijer, F. (Contributor) & McClelland, S. E. (Contributor), figshare Academic Research System, 20-okt.-2022
DOI: 10.6084/m9.figshare.21376239.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Replication_stress_generates_distinctive_landscapes_of_DNA_copy_number_alterations_and_chromosome_scale_losses/21376239/1
Dataset
Knipsels
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Death receptors in normal and malignant tissues
14/03/2004
1 Mediabijdrage
Pers / media: Expert Comment › Professional