Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

Cohen-Sharir, Y., McFarland, J. M., Abdusamad, M., Marquis, C., Bernhard, S. V., Kazachkova, M., Tang, H., Ippolito, M. R., Laue, K., Zerbib, J., Malaby, H. L. H., Jones, A., Stautmeister, L-M., Bockaj, I., Wardenaar, R., Lyons, N., Nagaraja, A., Bass, A. J., Spierings, D. C. J., Foijer, F. & 6 anderen, Beroukhim, R., Santaguida, S., Golub, T. R., Stumpff, J., Storchová, Z. & Ben-David, U., 18-feb-2021, In: Nature. 590, 7846, 29 blz.

Onderzoeksoutput › Academic › peer review

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

Nelson, L., Tighe, A., Golder, A., Littler, S., Bakker, B., Moralli, D., Murtuza Baker, S., Donaldson, I. J., Spierings, D. C. J., Wardenaar, R., Neale, B., Burghel, G. J., Winter-Roach, B., Edmondson, R., Clamp, A. R., Jayson, G. C., Desai, S., Green, C. M., Hayes, A., Foijer, F. & 2 anderen, Morgan, R. D. & Taylor, S. S., 13-feb-2020, In: Nature Communications. 11, 1, 18 blz., 822.

Onderzoeksoutput › Academic › peer review

Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition

Schukken, K. M., Lin, Y-C., Bakker, P. L., Schubert, M., Preuss, S. F., Simon, J. E., van den Bos, H., Storchova, Z., Colomé-Tatché, M., Bastians, H., Spierings, D. C. & Foijer, F., feb-2020, In: Life science alliance. 3, 2, 15 blz., e201900499.

Onderzoeksoutput › Academic › peer review

Analysis of Released Circulating Tumor Cells During Surgery for Non-Small Cell Lung Cancer: are they what they appear to be?

Tamminga, M., de Wit, S., Van De Wauwer, C., van den Bos, H., Swennenhuis, J. F., Klinkenberg, T. J., Hiltermann, T. J. N., Andree, K. C., Spierings, D. C. J., Lansdorp, P. M., van den Berg, A., Timens, W., Terstappen, L. W. & Groen, H. J., apr-2020, In: Clinical Cancer Research. 26, 7, blz. 1656-1666 11 blz.

Onderzoeksoutput › Academic › peer review

Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway

Phan, T. P., Maryniak, A. L., Boatwright, C. A., Lee, J., Atkins, A., Tijhuis, A., Spierings, D. C., Bazzi, H., Foijer, F., Jordan, P. W., Stracker, T. H. & Holland, A. J., 23-nov-2020, In: The EMBO Journal. 1, 18 blz., 106118.

Onderzoeksoutput › Academic › peer review