Floris Grasmeijer

Zoekresultaten

• 2022

  Dry powder inhalation, part 1: Ancient history and precursors to modern dry powder inhalers

  de Boer, A. H., Hagedoorn, P. & Grasmeijer, F., 2022, In: Expert Opinion on Drug Delivery. 19, 9, blz. 1033-1044 12 blz.

  Onderzoeksoutput › peer review

  Open Access

  Bestand
  1 Citaat (Scopus)

  10 Downloads (Pure)

• Dry powder inhalation, part 2: the present and future

  de Boer, A. H., Hagedoorn, P. & Grasmeijer, F., 2022, In: Expert Opinion on Drug Delivery. 19, 9, blz. 1045-1059 15 blz.

  Onderzoeksoutput › peer review

  Open Access

  Bestand
  1 Citaat (Scopus)

  36 Downloads (Pure)

• Tolerability and pharmacokinetic evaluation of inhaled dry powder hydroxychloroquine in healthy volunteers

  de Reus, Y. A., Hagedoorn, P., Sturkenboom, M. G. G., Grasmeijer, F., Bolhuis, M. S., Sibum, I., Kerstjens, H. A. M., Frijlink, H. W. & Akkerman, O. W., 5-aug.-2022, In: PLoS ONE. 17, 8, 12 blz., e0272034.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  2 Citaten (Scopus)

  25 Downloads (Pure)
• 2021

  Geïnhaleerde levodopa voor het couperen van OFF-fases bij de ziekte van Parkinson

  Grasmeijer, F., Hagedoorn, P. & Luinstra, M., 11-okt.-2021, In: Tijdschrift voor Neurologie en Neurochirurgie. 122, 8, 5 blz., 8.

  Onderzoeksoutput › Professional

  Open Access

  Bestand
  4 Downloads (Pure)

• Natural and bioinspired excipients for dry powder inhalation formulations

  Zillen, D., Beugeling, M., Hinrichs, W. L. J., Frijlink, H. W. & Grasmeijer, F., dec.-2021, In: Current Opinion in Colloid and Interface Science. 56, 17 blz., 101497.

  Onderzoeksoutput › peer review

  Open Access

  Bestand
  13 Citaten (Scopus)

  261 Downloads (Pure)

• The pharmacokinetics of antibiotics in cystic fibrosis

  Akkerman-Nijland, A. M., Akkerman, O. W., Grasmeijer, F., Hagedoorn, P., Frijlink, H. W., Rottier, B. L., Koppelman, G. H. & Touw, D. J., jan.-2021, In: Expert Opinion on Drug Metabolism & Toxicology. 17, 1, blz. 53-68 16 blz.

  Onderzoeksoutput › peer review

  Open Access

  Bestand
  19 Citaten (Scopus)

  117 Downloads (Pure)
• 2020

  A comparative analysis of changes in pMDI drug dose delivery before and after detergent coating using five antistatic valved holding chambers

  Hagedoorn, P., Bawary, W., Frijlink, H. W. & Grasmeijer, F., mrt.-2020, In: Journal of Allergy and Clinical Immunology: In Practice. 8, 3, blz. 1124-1125.e4

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  10 Citaten (Scopus)

  140 Downloads (Pure)

• Automated Filling Equipment Allows Increase in the Maximum Dose to Be Filled in the Cyclops(R)High Dose Dry Powder Inhalation Device While Maintaining Dispersibility

  Sibum, I., Hagedoorn, P., Botterman, C. O., Frijlink, H. W. & Grasmeijer, F., jul.-2020, In: Pharmaceutics. 12, 7, blz. 1-14 14 blz., 645.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  6 Citaten (Scopus)

  60 Downloads (Pure)

• Colistin dry powder inhalation with the Twincer (TM): An effective and more patient friendly alternative to nebulization

  Akkerman-Nijland, A. M., Grasmeijer, F., Kerstjens, H. A. M., Frijlink, H. W., van der Vaart, H., Vonk, J. M., Hagedoorn, P., Rottier, B. L., Koppelman, G. H. & Akkerman, O. W., 24-sep.-2020, In: PLoS ONE. 15, 9, 12 blz., e0239658.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  6 Citaten (Scopus)

  84 Downloads (Pure)

• Comparing five antistatic valved holding chambers: How antistatic are they really?

  Hagedoorn, P., Grasmeijer, F., Bawari, W., Frijlink, H. W. & Grasmeijer, F., 7-sep.-2020, In: European Respiratory Journal. 56, 2 blz.

  Onderzoeksoutput › Academic

• Ook antistatische voorzetkamers zijn niet één-op-een uitwisselbaar bij inhalatietherapie

  Hagedoorn, P. & Grasmeijer, F., 1-feb.-2020, In: COPD & Astma bulletin huisartsengeneeskunde. 1, 1 blz.

  Onderzoeksoutput › Professional

  Open Access

  Bestand
  373 Downloads (Pure)

• Optimisation of an isoniazid dry powder formulation for pulmonary administration

  Sibum, I., Grasmeijer, F., Hagedoorn, P. & Frijlink, H. W., 1-apr.-2020, In: Journal of aerosol medicine and pulmonary drug delivery. 33, 2, blz. A2-A2 1 blz.

  Onderzoeksoutput › Academic

• Relative lung dose from antistatic valved holding chambers Reply

  Hagedoorn, P., Bawary, W., Frijlink, H. W. & Grasmeijer, F., mrt.-2020, In: Journal of Allergy and Clinical Immunology: In Practice. 8, 3, blz. 1166-1167 2 blz.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  35 Downloads (Pure)
• 2019

  Characterization and Formulation of Isoniazid for High-Dose Dry Powder Inhalation

  Sibum, I., Hagedoorn, P., Frijlink, H. W. & Grasmeijer, F., 13-mei-2019, In: Pharmaceutics. 11, 5, 15 blz., 233.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  17 Citaten (Scopus)

  170 Downloads (Pure)

• Dispersibility and Storage Stability Optimization of High Dose Isoniazid Dry Powder Inhalation Formulations with L-Leucine or Trileucine

  Sibum, I., Hagedoorn, P., Kluitman, M. P. G., Kloezen, M., Frijlink, H. W. & Grasmeijer, F., 25-dec.-2019, In: Pharmaceutics. 12, 1, 14 blz., 24.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  29 Citaten (Scopus)

  120 Downloads (Pure)

• Formulating Amikacin for dry powder inhalation

  Sibum, I., Grasmeijer, F., Hagedoorn, P. & Frijlink, H. W., 1-apr.-2019, In: Journal of aerosol medicine and pulmonary drug delivery. 32, 2, blz. A7-A7 1 blz.

  Onderzoeksoutput › Academic

• Pharmacokinetics and tolerability of inhaled levodopa from a new dry-powder inhaler in patients with Parkinson's disease

  Luinstra, M., Rutgers, W., van Laar, T., Grasmeijer, F., Begeman, A., Isufi, V., Steenhuis, L., Hagedoorn, P., de Boer, A. & Frijlink, H. W., 2019, In: Therapeutic advances in chronic disease. 10, 10 blz.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  12 Citaten (Scopus)

  225 Downloads (Pure)
• 2018

  Challenges for pulmonary delivery of high powder doses

  Sibum, I., Hagedoorn, P., de Boer, A. H., Frijlink, H. W. & Grasmeijer, F., 5-sep.-2018, In: International Journal of Pharmaceutics. 548, 1, blz. 325-336 12 blz.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  43 Citaten (Scopus)

  481 Downloads (Pure)

• Cross border, highly individualised treatment of a patient with challenging extensively drug-resistant tuberculosis

  Akkerman, O. W., Grasmeijer, F., de Lange, W. C. M., Kerstjens, H. A. M., de Vries, G., Bolhuis, M. S., Alffenaar, J-W., Frijlink, H. W., Smith, G., Gajraj, R., de Zwaan, R., Hagedoorn, P., Dedicoat, M., van Soolingen, D. & van der Werf, T. S., 22-mrt.-2018, In: European Respiratory Journal. 51, 3, 4 blz., 1702490.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  7 Citaten (Scopus)

  299 Downloads (Pure)

• FORMULATING ISONIAZID FOR DRY POWDER INHALATION BY SPRAY DRYING

  Sibum, I., Grasmeijer, F., Hagedoorn, P. & Frijlink, H. W., apr.-2018, In: Journal of aerosol medicine and pulmonary drug delivery. 31, 2, blz. A2-A2 1 blz.

  Onderzoeksoutput › Academic

• PHARMACOKINETIC EVALUATION AND TOLERABILITY OF INHALED DRY POWDER LEVODOPA IN PARKINSON'S DISEASE PATIENTS

  Luinstra, M., Rutgers, A. W. F., Vroegop, S. J., Begeman, A., Lexmond, A. J., Grasmeijer, F., Hagedoorn, P., de Boer, A. H. & Frijlink, H. W., apr.-2018, In: Journal of aerosol medicine and pulmonary drug delivery. 31, 2, blz. A9-A9 1 blz.

  Onderzoeksoutput › Academic

• RE-DESIGNING THE COLISTIMETHATE SODIUM TWINCER (R) FOR LARGE-SCALE PRODUCTION

  Grasmeijer, F., Hagedoorn, P. & de Boer, A. H., apr.-2018, In: Journal of aerosol medicine and pulmonary drug delivery. 31, 2, blz. A12-A12 1 blz.

  Onderzoeksoutput › Academic
• 2017

  Characterisation of jet-milled and spray dried isoniazid for pulmonary administration

  Sibum, I., Grasmeijer, F., Hagedoorn, P. & Frijlink, H. W., aug.-2017, In: Journal of aerosol medicine and pulmonary drug delivery. 30, 4, blz. A2 1 blz.

  Onderzoeksoutput › Academic

• Dry powder inhalation: past, present and future

  de Boer, A., Hagedoorn, P., Hoppentocht, M., Buttini, F., Grasmeijer, F. & Frijlink, H. W., apr.-2017, In: Expert Opinion on Drug Delivery. 14, 4, blz. 499-512 14 blz.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  168 Citaten (Scopus)

  1456 Downloads (Pure)
• 2016

  A LEVODOPA WITH L-LEUCINE INHALATION POWDER FOR USE IN PARKINSON'S DISEASE

  Luinstra, M., Grasmeijer, F., Hagedoorn, P. & Frijlink, H. W., jun.-2016, In: Journal of aerosol medicine and pulmonary drug delivery. 29, 3, blz. A15-A15 1 blz.

  Onderzoeksoutput › Academic

• In vitro evaluation of the Twincer colistin dry powder inhaler as a non-cough-inducing alternative to Colobreathe

  Hagedoorn, P., Grasmeijer, F., Hoppentocht, M., Akkerman, O., Frijlink, H. & De Boer, A., 1-sep.-2016, In: European Respiratory Journal. 48, Suppl.60

  Onderzoeksoutput › Academic

  Open Access
• 2015

  A levodopa dry powder inhaler for the treatment of Parkinson's disease patients in off periods

  Luinstra, M., Grasmeijer, F., Hagedoorn, P., Moes, J. R., Frijlink, H. W. & De Boer, A. H., nov.-2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 97, blz. 22-29 8 blz.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  31 Citaten (Scopus)

  196 Downloads (Pure)

• Can patients with Parkinson's disease use dry powder inhalers during off periods?

  Luinstra, M., Rutgers, A. W. F., Dijkstra, H., Grasmeijer, F., Hagedoorn, P., Vogelzang, J. M. J., Frijlink, H. W. & De Boer, A. H., 14-jul.-2015, In: PLoS ONE. 10, 7, 12 blz., e0132714.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  13 Citaten (Scopus)

  242 Downloads (Pure)

• Inhalation manoeuvre performed by Parkinson's patients during an off period

  Luinstra, M., Rutgers, W., Dijkstra, H., Grasmeijer, F., Hagedoorn, P., Vogelzang, J., Frijlink, H. & De Boer, A., 1-sep.-2015, In: European Respiratory Journal. 46, Supl. 59

  Onderzoeksoutput › Academic

• Recent advances in the fundamental understanding of adhesive mixtures for inhalation

  Grasmeijer, F., Grasmeijer, N., Hagedoorn, P., Frijlink, H. W. & de Boer, A. H., 2015, In: Current Pharmaceutical Design. 21, 40, blz. 5900-5914 15 blz.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  34 Citaten (Scopus)

  11 Downloads (Pure)

• The ability of Parkinson's disease patients to use dry powder inhalers during off periods

  Luinstra, M., Rutgers, W. A. W. F., Dijkstra, H., Grasmeijer, F., Hagedoorn, P., Vogelzang, J., Frijlink, H. W. & De Boer, A. H., 1-jun.-2015, In: Movement Disorders. 30, blz. 101 1 blz.

  Onderzoeksoutput › Academic
• 2014

  Adhesive mixtures for inhalation: the cohesion between formulation variables, inhalation variables and dispersion performance

  Grasmeijer, F., 2014, [S.l.]: [S.n.]. 193 blz.

  Onderzoeksoutput

  Open Access

  Bestand
  837 Downloads (Pure)

• A proposed definition of the 'activity' of surface sites on lactose carriers for dry powder inhalation

  Grasmeijer, F., Frijlink, H. W. & de Boer, A., 2-jun.-2014, In: European Journal of Pharmaceutical Sciences. 56, 1, blz. 102-104 3 blz.

  Onderzoeksoutput › Academic › peer review
  20 Citaten (Scopus)

• CARS microscopy as a tool for studying the distribution of micronised drugs in adhesive mixtures for inhalation

  Fussell, A. L., Grasmeijer, F., Frijlink, H. W., de Boer, A. H. & Offerhaus, H. L., jul.-2014, In: Journal of Raman Spectroscopy. 45, 7, blz. 495-500 6 blz.

  Onderzoeksoutput › Academic › peer review
  22 Citaten (Scopus)

• New mechanisms to explain the effects of added lactose fines on the dispersion performance of adhesive mixtures for inhalation

  Grasmeijer, F., Lexmond, A. J., van den Noort, M., Hagedoorn, P., Hickey, A. J., Frijlink, H. W. & de Boer, A., 28-jan.-2014, In: PLoS ONE. 9, 1, 11 blz., e87825.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  60 Citaten (Scopus)

  493 Downloads (Pure)

• The dispersion behaviour of dry powder inhalation formulations cannot be assessed at a single inhalation flow rate

  Grasmeijer, F. & de Boer, A. H., 25-apr.-2014, In: International Journal of Pharmaceutics. 465, 1-2, blz. 165-168 4 blz.

  Onderzoeksoutput › Academic › peer review
  5 Citaten (Scopus)

• THE INTERPLAY BETWEEN VARIABLES IN THE FORMULATION AND DISPERSION OF ADHESIVE MIXTURES FOR INHALATION

  Grasmeijer, F., Hagedoorn, P., Frijlink, H. W. & de Boer, A. H., aug.-2014, In: Journal of aerosol medicine and pulmonary drug delivery. 27, 4, blz. A27 1 blz.

  Onderzoeksoutput › Academic
• 2013

  Comparative in vitro performance of the new drug aclidinium in a novel multidose dry powder inhaler

  Gjaltema, D., Hagedoorn, P., Grasmeijer, F., Huijbers, B. G., Frijlink, H. W. & De Boer, A. H., 1-sep.-2013, In: European Respiratory Journal. 42

  Onderzoeksoutput › Academic

• Drug content effects on the dispersion performance of adhesive mixtures for inhalation

  Grasmeijer, F., Hagedoorn, P., Frijlink, H. W. & de Boer, A. H., 14-aug.-2013, In: PLoS ONE. 8, 8, 12 blz., e71339.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  34 Citaten (Scopus)

  301 Downloads (Pure)

• Mixing time effects on the dispersion performance of adhesive mixtures for inhalation

  Grasmeijer, F., Hagedoorn, P., Frijlink, H. W. & de Boer, A., 2-jul.-2013, In: PLoS ONE. 8, 7, 18 blz., e69263.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand
  27 Citaten (Scopus)

  256 Downloads (Pure)

• The effect of mixing time on drug agglomeration and detachment for adhesive mixtures containing fine lactose carriers

  Grasmeijer, F., Hagedoorn, P., Frijlink, H. W. & de Boer, A. H., 1-okt.-2013, In: Journal of aerosol medicine and pulmonary drug delivery. 26, 5, blz. 7 1 blz.

  Onderzoeksoutput › Academic
• 2012

  Characterisation of high dose aerosols from dry powder inhalers

  Grasmeijer, F., Hagedoorn, P., Frijlink, H. W. & de Boer, A. H., 1-nov.-2012, In: International Journal of Pharmaceutics. 437, 1-2, blz. 242-249 8 blz.

  Onderzoeksoutput › Academic › peer review
  18 Citaten (Scopus)
• 2011

  Aerosol drug delivery: developments in device design and clinical use

  Rottier, B., Grasmeijer, F., Hagedoorn, P. & de Boer, A. H., 10-sep.-2011, In: LANCET. 378, 9795, blz. 981-982 2 blz.

  Onderzoeksoutput › Academic › peer review

• Characterisation of high dose dry powder aerosols by cascade impaction and laser diffraction analysis

  Grasmeijer, F., Hagedoorn, P., Frijlink, H. W. & De Boer, A. H., dec.-2011, In: Journal of aerosol medicine and pulmonary drug delivery. 24, 6, blz. 318 1 blz.

  Onderzoeksoutput › Academic

• Investigations into the mechanisms of drug particle detachment from carriers in adhesive mixtures for inhalation

  Grasmeijer, F., Hagedoorn, P., Frijlink, H. W. & De Boer, A. H., jun.-2011, In: Journal of aerosol medicine and pulmonary drug delivery. 24, 3, blz. 44 1 blz.

  Onderzoeksoutput › Academic