Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Persoonlijk profiel
Speerpunten
- Physiology and pathophysiology of the enterohepatic circulation in humans and experimental animals: hepatic and intestinal transport systems, mechanisms of bile formation and cholestasis, (patho)physiology of biliary lipid secretion, metabolic control by bile acids via newly identified signaling cascades
- Hepatic lipid metabolism in humans and experimental animals: lipoprotein assembly and secretion, causes and consequences of hepatic steatosis, interactions between carbohydrate and lipid metabolism, inborn errors of metabolism, inflammatory pathways, role of nuclear receptors (LXR, CHREBP)
- Regulation of cholesterol synthesis and trafficking: transcription factors and nuclear receptors (SREBP/PPAR/FXR/LXR) and transporter proteins, perinatal development, metabolic programming, application of stable isotope approaches
- Quantification of metabolic fluxes by stable isotope procedures
Netwerk
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis
Dehondt, H., Marino, A., Butruille, L., Mogilenko, D. A., Nzoussi Loubota, A. C., Chávez-Talavera, O., Dorchies, E., Vallez, E., Haas, J., Derudas, B., Bongiovanni, A., Tardivel, M., Kuipers, F., Lefebvre, P., Lestavel, S., Tailleux, A., Dombrowicz, D., Caron, S. & Staels, B., mrt.-2023, In: Molecular metabolism. 69, 13 blz., 101686.Onderzoeksoutput › Academic › peer review
Open AccessBestand3 Downloads (Pure) -
Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases
Zhan, N., Wang, B., Martens, N., Liu, Y., Zhao, S., Voortman, G., van Rooij, J., Leijten, F., Vanmierlo, T., Kuipers, F., Jonker, J. W., Bloks, V. W., Lütjohann, D., Palumbo, M., Zimetti, F., Adorni, M. P., Liu, H. & Mulder, M. T., 9-jan.-2023, In: International Journal of Molecular Sciences. 24, 2, 23 blz., 1290.Onderzoeksoutput › Academic › peer review
Open AccessBestand12 Downloads (Pure) -
Intestinal Farnesoid X Receptor Modulates Duodenal Surface Area but Does Not Control Glucose Absorption in Mice
Yang, J., van Dijk, T. H., Koehorst, M., Havinga, R., de Boer, J. F., Kuipers, F. & van Zutphen, T., 18-feb.-2023, In: International Journal of Molecular Sciences. 24, 4, 19 blz., 4132.Onderzoeksoutput › Academic › peer review
Open AccessBestand3 Downloads (Pure) -
Role of bile acid receptor FXR in development and function of brown adipose tissue
Yang, J., de Vries, H. D., Mayeuf-Louchart, A., Stroeve, J. H., Bloks, V. W., Koehorst, M., Duez, H., Staels, B., Kuipers, F. & van Zutphen, T., 2023, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 32 blz., 159257.Onderzoeksoutput › Academic › peer review
Open AccessBestand2 Citaten (Scopus)3 Downloads (Pure) -
Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans
Zhong, S., Chèvre, R., Castaño Mayan, D., Corlianò, M., Cochran, B. J., Sem, K. P., van Dijk, T. H., Peng, J., Tan, L. J., Hartimath, S. V., Ramasamy, B., Cheng, P., Groen, A. K., Kuipers, F., Goggi, J. L., Drum, C., van Dam, R. M., Tan, R. S., Rye, K. A., Hayden, M. R., & 6 anderen, 1-nov.-2022, In: The Journal of Clinical Investigation. 132, 21, 12 blz., e152961.Onderzoeksoutput › Academic › peer review
Open AccessBestand1 Citaat (Scopus)4 Downloads (Pure)
Activiteiten
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Supervision of PhD student Sandra Nagy
Folkert Kuipers (Supervisor), Annemieke Hoek (Supervisor) & U.J.F. Tietge (Supervisor)
23-sep.-2020Activiteit: Supervision and examination of PhD students of the UG › Academic
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Dutch Association for Diabetes Research (NVDO) (Externe Organisatie)
Folkert Kuipers (Member)
2019Activiteit: Membership › Professional
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European Atherosclerosis Society (Externe Organisatie)
Folkert Kuipers (Member)
2019Activiteit: Membership › Professional
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Nederlandse Vereniging voor Gastro-Enterologie(NVGE) (Externe Organisatie)
Folkert Kuipers (Member)
2019Activiteit: Membership › Professional
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Nederlandse Vereniging voor Hepatologie (NVH) (Externe Organisatie)
Folkert Kuipers (Member)
2019Activiteit: Membership › Professional
Datasets
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Data for: Dynamic binning peak detection and assessment of various lipidomics liquid chromatography-mass spectrometry pre-processing platforms
Horvatovich, P. (Contributor), Kuipers, F. (Contributor), Zhang, W. (Contributor), Kema, I. (Contributor), Barcaru, A. (Contributor) & Feng, X. (Contributor), Mendeley Data, 25-mei-2021
DOI: 10.17632/xnzwg3n5w5.1, https://data.mendeley.com/datasets/xnzwg3n5w5
Dataset
Knipsels
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De rol van het microbioom bij het ontstaan van hart- en vaatziekten
Debby Koonen & Folkert Kuipers
01/05/2019
1 item van Media-aandacht
Pers / media: Onderzoek › Popular