Folkert Kuipers

Zoekresultaten

• 2022

  Total, primary, and secondary serum bile acid changes and pruritus improvement during odevixibat treatment in patients with progressive familial intrahepatic cholestasis

  Verkade, H. J., Kuipers, F., Ni, Q. & Valcheva, V., jul.-2022, In: Journal of Hepatology. 77, blz. S517-S518 2 blz.

  Onderzoeksoutput › Academic
• 2021

  Low production of 12 alpha-hydroxylated bile acids prevents hepatic steatosis in mice with a human-like bile acid pool by reducing fat absorption

  Li, R., Palmiotti, A., de Vries, H. D., Hovingh, M. V., Koehorst, M., Mulder, N. L., Zhang, Y., Kats, K., Bloks, V. W., Fu, J., Verkade, H. J., de Boer, J. F. & Kuipers, F., okt.-2021, In: Hepatology. 74, S1, blz. 1077A-1078A 2 blz.

  Onderzoeksoutput › Academic

• Natural variation of serum bile acid levels and pruritus in children with progressive familial intrahepatic cholestasis: Pretreatment data from patients in the phase 3 pedfic 1 study

  Verkade, H. J., Kuipers, F., Yu, Q., Valcheva, V., Horn, P. & Kjems, L., okt.-2021, In: Hepatology. 74, blz. 1171A-1172A 2 blz.

  Onderzoeksoutput › Academic

• Pretreatment serum bile acid parameters and predictability of response to odevixibat, an ileal bile acid transport inhibitor, in children with progressive familial intrahepatic cholestasis

  Verkade, H., Kuipers, F., Ni, Q., Valcheva, V., Horn, P., Mattsson, J., Gillberg, P.-G. & Kjems, L., jul.-2021, In: Journal of Hepatology. 75, blz. S688-S689 2 blz.

  Onderzoeksoutput › Academic

• URSODEOXYCHOLIC ACID TREATMENT OF MOTHERS DURING PREGNANCY AND SUCKLING PREVENTS NEONATAL CHOLESTASIS IN NEWBORN Cyp2c70-/- MICE WITH A HUMAN-LIKE BILE ACID POOL

  de Vries, H., Palmiotti, A., Li, R., Hovingh, M., Mulder, N., Koehorst, M., Van Zutphen, T., Kuipers, F. & De Boer, J. F., okt.-2021, In: Hepatology. 74, blz. 278A-279A 2 blz.

  Onderzoeksoutput › Academic
• 2019

  A humanized bile acid pool induced by somatic CRISPR/Cas9-mediated deletion of Cyp2c70 modulates effects of pharmacological FXR activation in mice

  de Boer, J. F., Verkade, E., Mulder, N. L., de Vries, H. D., Huijkman, N., Koehorst, M., Boer, T., Wolters, J. C., Bloks, V. W., van de Sluis, B. & Kuipers, F., apr.-2019, In: Journal of Hepatology. 70, blz. E25-E26 2 blz.

  Onderzoeksoutput › Academic

• A HUMAN-LIKE COMPOSITION OF THE CIRCULATING BILE ACID POOL IMPACTS ON PLASMA LDL CHOLESTEROL IN MICE

  De Boer, J. F., de Vries, H. D., Palmiotti, A., Li, R., Mulder, N. L., Hovingh, M. V., Koehorst, M., Kloosterhuis, N. J., Bloks, V. W., van de Sluis, B. & Kuipers, F., aug.-2019, In: Atherosclerosis. 287, blz. E14-E14 1 blz.

  Onderzoeksoutput › Academic

• GENDER-SPECIFIC DIFFERENCES AT BOTH EXTREME ENDS OF THE LDL CHOLESTEROL DISTRIBUTION CURVE

  Rimbert, A., Balder, J. W., Zhang, X., Wolters, K., Lansberg, P., Viel, M., Kanninga, R., Johansson, L., Bloks, V., van Daasen, M., Koehorst, M., Kuipers, F., Sinke, R., Groen, A., Dallinga-Thie, G. & Kuivenhoven, J. A., aug.-2019, In: Atherosclerosis. 287, blz. E64 1 blz.

  Onderzoeksoutput › Academic

• Relationship between liver size and liver function in mice

  Ronda, O., Havinga, H., van de Heijning, B. J. M., Kuipers, F. & Verkade, H., 15-mei-2019, In: Journal of Pediatric Gastroenterology and Nutrition. 68, blz. 750

  Onderzoeksoutput › Academic

  • Very Low Density Lipoprotein 100%
  • Liver Function 100%
  • Bile Acid 100%
  • Lipoprotein Secretion 100%
  • Mouse 100%

• WHAT IS THE ORIGIN OF SEVERE HYPERCHOLESTEROLEMIA IN A LARGE COHORT OF EMIRATIS WITH A HIGH PREVALANCE OF TYPE 2 DIABETES

  Rimbert, A., Kuivenhoven, J. A., Lansberg, P., Viel, M., Kanninga, R., Johansson, L., Kuipers, F., Bloks, V., van Faassen, M., Koehorst, M., Sinke, R., Daggag, H., Al Tikriti, A. & Barakat, M. T., aug.-2019, In: Atherosclerosis. 287, blz. E198-E199 2 blz.

  Onderzoeksoutput › Academic
• 2018

  Dietary lipid structure in early life does not program fat absorption in later life: Journal of Pediatric Gastroenterology and Nutrition

  Ronda, O. A. H. O., Havinga, R., Van de Heijning, B., Kuipers, F. & Verkade, H. J., 2018, In: Journal of Pediatric Gastroenterology and Nutrition. 66, 1179 blz.

  Onderzoeksoutput › Academic

• Dietary lipid structure in early life does not program fat absorption in later life

  Ronda, O., Havinga, R., van de Heijning, B., Kuipers, F. & Verkade, H., apr.-2018, In: The FASEB Journal. 32, 1, 2 blz.

  Onderzoeksoutput › Academic

• FXR activation normalizes dyslipidemia and alleviates obesity in western-type diet–fed APOE*3-Leiden.CETP transgenic mice

  Paalvast, Y., Zhou, E., Mulder, N. L., Koehorst, M., Boverhof, R., van Dijk, K. W., Rensen, P. C. N., Kuivenhoven, J. A., Kremoser, C., Wang, Y., Kuipers, F., Groen, A. K. & de Boer, J. F., aug.-2018, In: Atherosclerosis. 275, blz. E10 1 blz.

  Onderzoeksoutput › Academic

• Microbial impact on plasma metabolites is linked to the cardiovascular risk and phenotypes

  Lifelines-DEEP Cohort Study & BBMRI Metabolomics Consortium, jun.-2018, In: Atherosclerosis supplements. 32, blz. 118-119 2 blz.

  Onderzoeksoutput › Academic
• 2009

  Retinoids Decrease Plasma HDL Cholesterol Levels by Increasing Cholesteryl Ester Transfer Protein Expression and Activity in Transgenic Mice

  Gautier, T., Claudel, T., Le Guern, N., Lagrost, L., Kuipers, F. & Tietge, U. J., jul.-2009, In: Arteriosclerosis thrombosis and vascular biology. 29, 7, blz. E107-E107 1 blz.

  Onderzoeksoutput › Academic

  15 Citaten (Scopus)
• 2007

  Fish oil does not prevent high fat diet-induced peripheral insulin resistance in mice

  Oosterveer, M. H., Schreurs, M., van Dijk, T. H., Havinga, R., van den Berg, S. A., Dijk, K.W.-V., Kuipers, F. & Reijngoud, D., jun.-2007, In: Diabetes. 56, blz. A454-A455 2 blz.

  Onderzoeksoutput › Academic
• 2006

  Phosphatidylethanolamine N-methyltransferase pathway of phosphatidylcholine biosynthesis is important for the amount of biliary phosphatidyleholine secretion

  Verkade, H. J., Havinga, R., Shields, D. J., Wolters, H., Bloks, V., Kuipers, F., Vance, D. E. & Agellon, L. B., apr.-2006, In: Gastroenterology. 130, 4, blz. A815-A816 2 blz.

  Onderzoeksoutput › Academic
• 2005

  Essential fatty acid deficiency in mice is associated with hepatic steatosis and secretion of large VLDL particles

  Werner, A., Havinga, R., Bos, T., Bloks, V., Kuipers, F. & Verkade, H., apr.-2005, In: Gastroenterology. 128, 4, blz. A704-A704 1 blz.

  Onderzoeksoutput › Academic
• 2001

  Zonal distribution of apolipoprotein B messenger RNA in rodent liver

  Baller, J., Plosch, T., Wolters, H., Mensenkamp, A., van Goor, H., van den Berg, A. & Kuipers, F., apr.-2001, In: Arteriosclerosis thrombosis and vascular biology. 21, 4, blz. 667-667 1 blz.

  Onderzoeksoutput › Academic
• 1998

  Bile duct proliferation and biliary fibrosis associated with altered bile composition in a mouse model of erythropoetic protoporphyria.

  Meerman, L., Koopen, N., Bloks, [. V., van Goor, H., Havinga, R., Muller, M., Kuipers, F. & Jansen, P., 15-apr.-1998, In: Gastroenterology. 114, 4, blz. A1300-A1300 1 blz.

  Onderzoeksoutput › Academic

• Detection of intestinal fat malabsorption due to impaired lipolysis by the ¹³C–mixed triglyceride breath test in rats

  Kalivianakis, M., Elstrodt, J., Havinga, R., Kuipers, F., Stellaard, F., Vonk, R. J. & Verkade, H. J., dec.-1998, In: European Journal of Gastroenterology and Hepatology. 10, 12, blz. A66 1 blz.

  Onderzoeksoutput › Academic

• Glutathione is required for the induced expression of iNOS in rat hepatocytes in vivo and in vitro

  Vos, T., van Goor, H., de Jager-Krikken, A., Leuvenink, R., Kuipers, F., Jansen, P. & Moshage, H., okt.-1998, In: Hepatology. 28, 4, blz. 254A-254A 1 blz.

  Onderzoeksoutput › Academic

• Impaired chylomicron formation in mdr2 P-glycoprotein-deficient mice lacking biliary lipid secretion

  Voshol, P., Minich, D., Havinga, R., van Goor, H., OudeElferink, R., Verkade, H., Groen, A. & Kuipers, F., 27-okt.-1998, In: Circulation. 98, 17, blz. 35-35 1 blz.

  Onderzoeksoutput › Academic

• The canalicular bile salt exporting protein BSEP is not expressed in patients with progressive familial intrahepatic cholestasis type 2.

  Jansen, P., Hooiveld, G., Jacquemin, E., Sokal, E., van Goor, H., Koning, J., Kuipers, F., Stellaard, F., Hadchouel, M. & Muller, M., okt.-1998, In: Hepatology. 28, 4, blz. 498A-498A 1 blz.

  Onderzoeksoutput › Academic
• 1997

  Hepatic lipid accumulation in transgenic mice carrying the apolipoprotein E3 Leiden gene

  Kuipers, F., Mensenkamp, A., vanGoor, H., Bloks, [. V., Hofker, M., Jong, M., vanVlijmen, B. & Havekes, L., 21-okt.-1997, In: Circulation. 96, 8, blz. 588-588 1 blz.

  Onderzoeksoutput › Academic