Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
- 1 - 50 van 197 resultaten
Zoekresultaten
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2025
Artificial ER-Mitochondrion Tethering Restores Erg6 Localization and Lipid Droplet Formation in Hansenula polymorpha Δpex23 and Δpex29 Cells.
Chen, H., de Boer, R., Lamb, D. C., Kelly, S. L. & van der Klei, I. J., 2025, In: Contact. 8, 9 blz., 25152564251336908.Onderzoeksoutput › Academic › peer review
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Coordination of cytochrome bc1 complex assembly at MICOS
Zerbes, R. M., Colina-Tenorio, L., Bohnert, M., von der Malsburg, K., Peikert, C. D., Mehnert, C. S., Perschil, I., Klar, R. F. U., de Boer, R., Kram, A., van der Klei, I., Oeljeklaus, S., Warscheid, B., Rampelt, H. & van der Laan, M., jan.-2025, In: Embo Reports. 26, blz. 353-384 32 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand2 Citaten (Scopus)36 Downloads (Pure) -
Docosahexaenoic acid prevents peroxisomal and mitochondrial protein loss in a murine hepatic organoid model of severe malnutrition
Horcas-Nieto, J. M., Rios-Ocampo, W. A., Langelaar-Makkinje, M., de Boer, R., Gerding, A., Chornyi, S., Martini, I. A., Wolters, J. C., Wanders, R. J. A., Waterham, H. R., Van der Klei, I. J., Bandsma, R. H. J., Jonker, J. W. & Bakker, B. M., aug.-2025, In: Biochimica et biophysica acta-Molecular basis of disease. 1871, 6, 12 blz., 167849.Onderzoeksoutput: Article › Academic › peer review
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Integrative Omics reveals changes in the cellular landscape of peroxisome-deficient pex3 yeast cells
Kosir, T., Das, H., Pedersen, M. P., Richard, A.-K., Anteghini, M., Martins Dos Santos, V., Oeljeklaus, S., van der Klei, I. J. & Warscheid, B., 20-feb.-2025, In: Microbial Cell. 12, 1, blz. 9-33 25 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand24 Downloads (Pure) -
2024
Hansenula polymorpha cells lacking the ER-localized peroxins Pex23 or Pex29 show defects in mitochondrial function and morphology
Chen, H., de Boer, R., Krikken, A. M., Wu, F. & van der Klei, I., 21-mei-2024, In: Open Biology. 13, 5, 12 blz., bio060271.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand1 Citaat (Scopus)55 Downloads (Pure) -
Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells
Jansen, R. L. M., de Boer, R., de Lange, E. M. F., Koster, J., Vlijm, R., Waterham, H. R. & van der Klei, I. J., aug.-2024, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1871, 6, 12 blz., 119754.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand134 Downloads (Pure) -
STED super-resolution microscopy unveils the dynamics of Atg30 on yeast Pex3-labeled peroxisomes
de Lange, E. M. F., Mol, F. N., van der Klei, I. J. & Vlijm, R., 16-aug.-2024, In: Iscience. 27, 8, 20 blz., 110481.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand83 Downloads (Pure) -
The Hansenula polymorpha mitochondrial carrier family protein Mir1 is dually localized at peroxisomes and mitochondria
Pedersen, M. P., Wolters, J. C., de Boer, R., Krikken, A. M. & van der Klei, I. J., jun.-2024, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1871, 5, 14 blz., 119742.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand1 Citaat (Scopus)85 Downloads (Pure) -
2023
Novel targeting assay uncovers targeting information within peroxisomal ABC transporter Pxa1
Jansen, R. L. M., van den Noort, M., Krikken, A. M., Bibi, C., Böhm, A., Schuldiner, M., Zalckvar, E. & van der Klei, I. J., jun.-2023, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1870, 5, 11 blz., 119471.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand1 Citaat (Scopus)130 Downloads (Pure) -
2022
Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth
Rampelt, H., Wollweber, F., Licheva, M., de Boer, R., Perschil, I., Steidle, L., Becker, T., Bohnert, M., van der Klei, I., Kraft, C., van der Laan, M. & Pfanner, N., 25-jan.-2022, In: Cell reports. 38, 4, 12 blz., 110290.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand24 Citaten (Scopus)123 Downloads (Pure) -
Structure-function analysis of the ER-peroxisome contact site protein Pex32
Wu, F. & van der Klei, I. J., 2022, In: Frontiers in Cell and Developmental Biology. 10, 9 blz., 957871.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand3 Citaten (Scopus)73 Downloads (Pure) -
Yeast Vps13 is Crucial for Peroxisome Expansion in Cells With Reduced Peroxisome-ER Contact Sites
Yuan, W., Akşit, A., de Boer, R., Krikken, A. M. & van der Klei, I. J., 17-feb.-2022, In: Frontiers in Cell and Developmental Biology. 10, 10 blz., 842285.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand12 Citaten (Scopus)97 Downloads (Pure) -
2021
Comparative Genomics of Peroxisome Biogenesis Proteins: Making Sense of the PEX Proteins
Jansen, R. L. M., Santana-Molina, C., van den Noort, M., Devos, D. P. & van der Klei, I. J., 20-mei-2021, In: Frontiers in Cell and Developmental Biology. 9, 22 blz., 654163.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand58 Citaten (Scopus)132 Downloads (Pure) -
2020
Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement
Zielińska, A., Savietto, A., de Sousa Borges, A., Martinez, D., Berbon, M., Roelofsen, J. R., Hartman, A. M., de Boer, R., Van der Klei, I. J., Hirsch, A. K., Habenstein, B., Bramkamp, M. & Scheffers, D.-J., 14-jul.-2020, In: eLife. 9, blz. 1-21 21 blz., e57179.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand33 Citaten (Scopus)337 Downloads (Pure) -
Hansenula polymorpha Pex37 is a peroxisomal membrane protein required for organelle fission and segregation
Singh, R., Manivannan, S., Krikken, A. M., de Boer, R., Bordin, N., Devos, D. P. & van der Klei, I. J., 1-mei-2020, In: The FEBS Journal. 287, 9, blz. 1742-1757 16 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand8 Citaten (Scopus)176 Downloads (Pure) -
Hansenula Polymorpha Vac8: A Vacuolar Membrane Protein Required for Vacuole Inheritance and Nucleus-Vacuole Junction Formation
Singh, R., Wróblewska, J., de Boer, R. & van der Klei, I. J., 2020, In: Contact. 3, blz. 1-8 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand3 Citaten (Scopus)50 Downloads (Pure) -
Peroxisome retention involves Inp1-dependent peroxisome-plasma membrane contact sites in yeast
Krikken, A. M., Wu, H., de Boer, R., Devos, D. P., Levine, T. P. & van der Klei, I. J., 5-okt.-2020, In: The Journal of Cell Biology. 219, 10, 11 blz., e201906023.Onderzoeksoutput › Academic › peer review
Open AccessBestand13 Citaten (Scopus)138 Downloads (Pure) -
Pex24 and Pex32 are required to tether peroxisomes to the ER for organelle biogenesis, positioning and segregation in yeast
Wu, F., de Boer, R., Krikken, A. M., Akşit, A., Bordin, N., Devos, D. P. & van der Klei, I. J., 17-aug.-2020, In: Journal of Cell Science. 133, 16, 16 blz., jcs.246983.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand22 Citaten (Scopus)100 Downloads (Pure) -
2019
Peroxisome development in yeast is associated with the formation of Pex3-dependent peroxisome-vacuole contact sites
Wu, H., de Boer, R., Krikken, A. M., Akşit, A., Yuan, W. & van der Klei, I. J., mrt.-2019, In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866, 3, blz. 349-359 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand29 Citaten (Scopus)150 Downloads (Pure) -
Peroxisome Maintenance Depends on De Novo Peroxisome Formation in Yeast Mutants Defective in Peroxisome Fission and Inheritance
Wróblewska, J. P. & van der Klei, I. J., 17-aug.-2019, In: International Journal of Molecular Sciences. 20, 16, 17 blz., 4023.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand6 Citaten (Scopus)193 Downloads (Pure) -
2018
Assembly of the Mitochondrial Cristae Organizer Mic10 is Regulated by Mic26-Mic27 Antagonism and Cardiolipin
Rampelt, H., Wollweber, F., Gerke, C., de Boer, R., van der Klei, I. J., Bohnert, M., Pfanner, N. & van der Laan, M., 22-jun.-2018, In: Journal of Molecular Biology. 430, 13, blz. 1883-1890 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand44 Citaten (Scopus)203 Downloads (Pure) -
Yeast cells contain a heterogeneous population of peroxisomes that segregate asymmetrically during cell division
Kumar, S., de Boer, R. & van der Klei, I. J., 7-feb.-2018, In: Journal of Cell Science. 131, 3, 7 blz., jcs.207522.Onderzoeksoutput › Academic › peer review
Open AccessBestand27 Citaten (Scopus)322 Downloads (Pure) -
Yeast peroxisomes: How are they formed and how do they grow?
Aksit, A. & van der Klei, I. J., dec.-2018, In: International journal of biochemistry & cell biology. 105, blz. 24-34 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand30 Citaten (Scopus)344 Downloads (Pure) -
2017
Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins
Wroblewska, J. P., Cruz-Zaragoza, L. D., Yuan, W., Schummer, A., Chuartzman, S. G., de Boer, R., Oeljeklaus, S., Schuldiner, M., Zalckvar, E., Warscheid, B., Erdmann, R. & van der Klei, I. J., okt.-2017, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 10, blz. 1656-1667 12 blz., bbamcr.2017.05.021.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand26 Citaten (Scopus)67 Downloads (Pure) -
2016
Impaired biosynthesis of the non-bilayer lipids phosphatidylethanolamine or cardiolipin does not affect peroxisome biogenesis and proliferation in Saccharomyces cerevisiae
Kawalek, A., Jagadeesan, C. & van der Klei, I. J., 11-nov.-2016, In: Biochemical and Biophysical Research Communications. 480, 2, blz. 228-233 6 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand4 Citaten (Scopus)86 Downloads (Pure) -
Stress exposure results in increased peroxisomal levels of yeast Pnc1 and Gpd1, which are imported via a piggy-backing mechanism
Kumar, S., Singh, R., Williams, C. P. & van der Klei, I. J., jan.-2016, In: Biochimica et Biophysica Acta-Molecular Cell Research. 1863, 1, blz. 148-156 9 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand31 Citaten (Scopus)80 Downloads (Pure) -
The birth of yeast peroxisomes
Yuan, W., Veenhuis, M. & van der Klei, I. J., mei-2016, In: Biochimica et biophysica acta. 1863, 5, blz. 902-910 9 blz., 17661.Onderzoeksoutput › Academic › peer review
Open Access29 Citaten (Scopus) -
2015
Central role of mic10 in the mitochondrial contact site and cristae organizing system
Bohnert, M., Zerbes, R. M., Davies, K. M., Mühleip, A. W., Rampelt, H., Horvath, S. E., Boenke, T., Kram, A., Perschil, I., Veenhuis, M., Kühlbrandt, W., van der Klei, I. J., Pfanner, N. & van der Laan, M., 5-mei-2015, In: Cell Metabolism. 21, 5, blz. 747-755 9 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand125 Citaten (Scopus)298 Downloads (Pure) -
Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan
Lefevre, S. D., Kumar, S. & van der Klei, I. J., 3-apr.-2015, In: Cell Cycle. 14, 11, blz. 1698-1703 6 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand23 Citaten (Scopus)167 Downloads (Pure) -
Phosphorylation of Pex11p does not regulate peroxisomal fission in the yeast Hansenula polymorpha
Thomas, A. S., Krikken, A. M., van der Klei, I. J. & Williams, C. P., 2015, In: Scientific Reports. 5, blz. 1-11 11 blz., 11493.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand12 Citaten (Scopus)302 Downloads (Pure) -
The membrane remodeling protein Pex11p activates the GTPase Dnm1p during peroxisomal fission
Williams, C., Opalinski, L., Landgraf, C., Costello, J., Schrader, M., Krikken, A. M., Knoops, K., Kram, A. M., Volkmer, R. & van der Klei, I. J., 4-mei-2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 20, blz. 6377-6382 6 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand64 Citaten (Scopus)64 Downloads (Pure) -
Yeast pex1 cells contain peroxisomal ghosts that import matrix proteins upon reintroduction of Pex1
Knoops, K., de Boer, R., Kram, A. & van der Klei, I. J., 7-dec.-2015, In: The Journal of Cell Biology. 211, 5, blz. 955-962 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand24 Citaten (Scopus)301 Downloads (Pure) -
2014
A critical reflection on the principles of peroxisome formation in yeast
Veenhuis, M. & van der Klei, I. J., 20-mrt.-2014, In: Frontiers in Physiology. 5, 8 blz., 110.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand26 Citaten (Scopus)356 Downloads (Pure) -
At neutral pH the chronological lifespan of Hansenula polymorpha increases upon enhancing the carbon source concentration
Kawalek, A. & van der Klei, I., 20-mei-2014, In: Microbial Cell. 1, 6, blz. 189-202 14 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand3 Citaten (Scopus)185 Downloads (Pure) -
Evolving models for peroxisome biogenesis
Hettema, E. H., Erdmann, R., van der Klei, I. & Veenhuis, M., aug.-2014, In: Current Opinion in Cell Biology. 29C, blz. 25-30 6 blz.Onderzoeksoutput › Academic › peer review
64 Citaten (Scopus) -
Lipid droplet autophagy in the yeast Saccharomyces cerevisiae
van Zutphen, T., Todde, V., de Boer, R., Kreim, M., Hofbauer, H. F., Wolinski, H., Veenhuis, M., Klei, I. J. V. D. & Kohlwein, S. D., jan.-2014, In: Molecular Biology of the Cell. 25, 2, blz. 290-301 12 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand234 Citaten (Scopus)825 Downloads (Pure) -
Preperoxisomal vesicles can form in the absence of Pex3
Knoops, K., Manivannan, S., Cepinska, M. N., Krikken, A. M., Kram, A. M., Veenhuis, M. & van der Klei, I. J., 2014, In: The Journal of Cell Biology. 204, 5, blz. 659-668 10 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand69 Citaten (Scopus)541 Downloads (Pure) -
Uniform nomenclature for the mitochondrial contact site and cristae organizing system
Pfanner, N., van der Laan, M., Amati, P., Capaldi, R. A., Caudy, A. A., Chacinska, A., Darshi, M., Deckers, M., Hoppins, S., Icho, T., Jakobs, S., Ji, J., Kozjak-Pavlovic, V., Meisinger, C., Odgren, P. R., Park, S. K., Rehling, P., Reichert, A. S., Sheikh, M. S. & Taylor, S. S. & 8 anderen, , 31-mrt.-2014, In: The Journal of Cell Biology. 204, 7, blz. 1083-1086 4 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand215 Citaten (Scopus)768 Downloads (Pure) -
2013
Improving penicillin biosynthesis in Penicillium chrysogenum by glyoxalase overproduction
Scheckhuber, C. Q., Veenhuis, M. & van der Klei, I. J., jul.-2013, In: Metabolic Engineering. 18, blz. 36-43 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand8 Citaten (Scopus)623 Downloads (Pure) -
Lipid Droplets and Peroxisomes: Key Players in Cellular Lipid Homeostasis or A Matter of Fat-Store 'em Up or Burn 'em Down
Kohlwein, S. D., Veenhuis, M. & van der Klei, I. J., jan.-2013, In: Genetics. 193, 1, blz. 1-50 50 blz.Onderzoeksoutput › Academic › peer review
185 Citaten (Scopus)211 Downloads (Pure) -
Lumenal peroxisomal protein aggregates are removed by concerted fission and autophagy events
Manivannan, S., de Boer, R., Veenhuis, M. & van der Klei, I. J., 1-jul.-2013, In: Autophagy. 9, 7, blz. 1044-1056 13 blz.Onderzoeksoutput › Academic › peer review
30 Citaten (Scopus) -
Peroxisomal catalase deficiency modulates yeast lifespan depending on growth conditions
Kawalek, A., Lefevre, S. D., Veenhuis, M. & van der Klei, I. J., jan.-2013, In: Aging-Us. 5, 1, blz. 67-83 17 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand23 Citaten (Scopus)343 Downloads (Pure) -
Pexophagy-linked degradation of the peroxisomal membrane protein Pex3p involves the ubiquitin-proteasome system
Williams, C. & van der Klei, I. J., 23-aug.-2013, In: Biochemical and Biophysical Research Communications. 438, 2, blz. 395-401 7 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand29 Citaten (Scopus)633 Downloads (Pure) -
The significance of peroxisome function in chronological aging of Saccharomyces cerevisiae
Lefevre, S. D., van Roermund, C. W., Wanders, R. J. A., Veenhuis, M. & van der Klei, I. J., okt.-2013, In: Aging Cell. 12, 5, blz. 784-793 10 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand32 Citaten (Scopus)692 Downloads (Pure) -
2012
De Novo Peroxisome Biogenesis in Penicillium Chrysogenum Is Not Dependent on the Pex11 Family Members or Pex16
Opalinski, L., Bartoszewska, M., Fekken, S., Liu, H., de Boer, R., van der Klei, I., Veenhuis, M. & Kiel, J. A. K. W., 19-apr.-2012, In: PLoS ONE. 7, 4, 12 blz., e35490.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand20 Citaten (Scopus)951 Downloads (Pure) -
Extension of Yeast Chronological Lifespan by Methylamine
Kumar, S., Lefevre, S. D., Veenhuis, M. & van der Klei, I. J., 2-nov.-2012, In: PLoS ONE. 7, 11, 9 blz., e48982.Onderzoeksoutput › Academic › peer review
Open AccessBestand8 Citaten (Scopus)272 Downloads (Pure) -
Guidelines for the use and interpretation of assays for monitoring autophagy
et al., Carra, S., Kampinga, H. H., Kiel, J. A. K. W. & van der Klei, I. J., 1-apr.-2012, In: Autophagy. 8, 4, blz. 445-544 100 blz.Onderzoeksoutput: Article › Academic
2960 Citaten (Scopus) -
Metabolic engineering of beta-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis
Veiga, T., Gombert, A. K., Landes, N., Verhoeven, M. D., Kiel, J. A. K. W., Krikken, A. M., Nijland, J. G., Touw, H., Luttik, M. A. H., van der Toorn, J. C., Driessen, A. J. M., Bovenberg, R. A. L., van den Berg, M. A., van der Klei, I. J., Pronk, J. T. & Daran, J.-M., jul.-2012, In: Metabolic Engineering. 14, 4, blz. 437-448 12 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand23 Citaten (Scopus)483 Downloads (Pure) -
Peroxisomal Proteostasis Involves a Lon Family Protein That Functions as Protease and Chaperone
Bartoszewska, M., Williams, C., Kikhney, A., Opalinski, L., van Roermund, C. W. T., de Boer, R., Veenhuis, M. & van der Klei, I. J., 10-aug.-2012, In: The Journal of Biological Chemistry. 287, 33, blz. 27380-27395 16 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand49 Citaten (Scopus)437 Downloads (Pure) -
Pex19p Contributes to Peroxisome Inheritance in the Association of Peroxisomes to Myo2p
Otzen, M., Rucktaeschel, R., Thoms, S., Ernmrich, K., Krikken, A. M., Erdmann, R., van der Klei, I. J., Emmrich, K. & Krikken, A. M., jul.-2012, In: Traffic. 13, 7, blz. 947-959 13 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand24 Citaten (Scopus)872 Downloads (Pure)