Type I interferon-activated microglia are critical for neuromyelitis optica pathology

Wlodarczyk, A., Khorooshi, R., Marczynska, J., Holtman, I. R., Burton, M., Jensen, K. N., Blaabjerg, M., Meyer, M., Thomassen, M., Eggen, B. J. L., Asgari, N. & Owens, T., 26-nov-2020, In: Glia. blz. 1-11 11 blz.

Onderzoeksoutput › Academic › peer review

Brain cell type-specific enhancer-promoter interactome maps and disease-risk association

Nott, A., Holtman, I. R., Coufal, N. G., Schlachetzki, J. C. M., Yu, M., Hu, R., Han, C. Z., Pena, M., Xiao, J., Wu, Y., Keulen, Z., Pasillas, M. P., O'Connor, C., Nickl, C. K., Schafer, S. T., Shen, Z., Rissman, R. A., Brewer, J. B., Gosselin, D., Gonda, D. D. & 6 anderen, Levy, M. L., Rosenfeld, M. G., McVicker, G., Gage, F. H., Ren, B. & Glass, C. K., 29-nov-2019, In: Science. 366, 6469, blz. 1134-1139 50 blz.

Onderzoeksoutput › Academic › peer review

Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function

Link, V. M., Duttke, S. H., Chun, H. B., Holtman, I. R., Westin, E., Hoeksema, M. A., Abe, Y., Skola, D., Romanoski, C. E., Tao, J., Fonseca, G. J., Troutman, T. D., Spann, N. J., Strid, T., Sakai, M., Yu, M., Hu, R., Fang, R., Metzler, D., Ren, B. & 1 anderen, Glass, C. K., 14-jun-2018, In: Cell. 173, 7, blz. 1796-1809.e17 31 blz.

Onderzoeksoutput › Academic › peer review

Aging, microglia and cytoskeletal regulation are key factors in the pathological evolution of the APP23 mouse model for Alzheimer's disease

Janssen, L., Dubbelaar, M. L., Holtman, I. R., de Boer-Bergsma, J., Eggen, B. J. L., Boddeke, H. W. G. M., De Deyn, P. P. & Dam, van, D., feb-2017, In: Biochimica et biophysica acta-Molecular basis of disease. 1863, 2, blz. 395-405 11 blz.

Onderzoeksoutput › Academic › peer review

An environment-dependent transcriptional network specifies human microglia identity

Gosselin, D., Skola, D., Coufal, N. G., Holtman, I. R., Schlachetzki, J. C. M., Sajti, E., Jaeger, B. N., O'Connor, C., Fitzpatrick, C., Pasillas, M. P., Pena, M., Adair, A., Gonda, D. D., Levy, M. L., Ransohoff, R. M., Gage, F. H. & Glass, C. K., 23-jun-2017, In: Science. 356, 6344, blz. 1248-+ 12 blz.

Onderzoeksoutput › Academic › peer review