Karin Duitscher-Fransen

Zoekresultaten

• 2020

  Effect of Early Surgery vs Endoscopy-First Approach on Pain in Patients With Chronic Pancreatitis The ESCAPE Randomized Clinical Trial: The ESCAPE Randomized Clinical Trial

  Dutch Pancreatitis Study Grp, Issa, Y., Kempeneers, M. A., Bruno, M. J., Fockens, P., Poley, J.-W., Ahmed Ali, U., Bollen, T. L., Busch, O. R., Dejong, C. H., van Duijvendijk, P., van Dullemen, H. M., van Eijck, C. H., van Goor, H., Hadithi, M., Haveman, J.-W., Keulemans, Y., Nieuwenhuijs, V. B., Poen, A. C. & Rauws, E. A. & 9 anderen, Tan, A. C., Thijs, W., Timmer, R., Witteman, B. J., Besselink, M. G., van Hooft, J. E., van Santvoort, H. C., Dijkgraaf, M. G. & Boermeester, M. A., 21-jan.-2020, In: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 323, 3, blz. 237-247 11 blz.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand

  • Endoscopy 100%
  • Randomized Clinical Trial 100%
  • Chronic Pancreatitis 100%
  • Pancreas Function 37%
  • Quality of Life 25%
  196 Citaten (Scopus)

  428 Downloads (Pure)
• 2016

  Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes

  Franke, L., El Bannoudi, H., Jansen, D. T. S. L., Kok, K., Trynka, G., Diogo, D., Swertz, M., Fransen, K., Knevel, R., Gutierrez-Achury, J., Ärlestig, L., Greenberg, J. D., Kremer, J., Pappas, D. A., Kanterakis, A., Weersma, R. K., van der Helm-van Mil, A. H. M., Guryev, V., Rantapää-Dahlqvist, S. & Gregersen, P. K. & 6 anderen, Plenge, R. M., Wijmenga, C., Huizinga, T.W.-J., Ioan-Facsinay, A., Toes, R. E. M. & Zhernakova, A., 2016, In: European Journal of Human Genetics. 24, 2, blz. 263-270 8 blz.

  Onderzoeksoutput: Article › Academic › peer review

  • Receptor Gene 100%
  • Copy-Number Variation 100%
  • FCGR3B 44%
  • FCGR3A 44%
  • Low Copy Repeats 33%
  24 Citaten (Scopus)
• 2014

  Correlation of Genetic Risk and Messenger RNA Expression in a Th17/IL23 Pathway Analysis in Inflammatory Bowel Disease

  Fransen, K., van Sommeren, S., Westra, H. J., Veenstra, M., Lamberts, L. E., Modderman, R., Dijkstra, G., Fu, J., Wijmenga, C., Franke, L., Weersma, R. K. & van Diemen, C. C., mei-2014, In: Inflammatory Bowel Diseases. 20, 5, blz. 777-782 6 blz.

  Onderzoeksoutput: Article › Academic › peer review

  • Genetic Risk 100%
  • Messenger RNA 100%
  • Expression Quantitative Trait Loci 42%
  • Single Nucleotide Polymorphism 28%
  • Peripheral Blood Mononuclear Cell 28%
  19 Citaten (Scopus)
• 2013

  Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

  Smeekens, S. P., Ng, A., Kumar, V., Johnson, M. D., Plantinga, T. S., van Diemen, C., Arts, P., Verwiel, E. T. P., Gresnigt, M. S., Fransen, K., van Sommeren, S., Oosting, M., Cheng, S.-C., Joosten, L. A. B., Hoischen, A., Kullberg, B.-J., Scott, W. K., Perfect, J. R., van der Meer, J. W. M. & Wijmenga, C. & 2 anderen, Netea, M. G. & Xavier, R. J., jan.-2013, In: Nature Communications. 4, 10 blz., 1342.

  Onderzoeksoutput › Academic › peer review

  Open Access

  Bestand

  • Functional Genomics 100%
  • interferon 100%
  • Host Resistance 100%
  • Candida 100%
  • Candida Albicans 100%
  159 Citaten (Scopus)

  329 Downloads (Pure)
• 2012

  Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

  Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., McGovern, D. P., Hui, K. Y., Lee, J. C., Schumm, L. P., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z. & Abraham, C. & 31 anderen, Achkar, J.-P., Ahmad, T., Amininejad, L., Ananthakrishnan, A. N., Andersen, V., Andrews, J. M., Baidoo, L., Balschun, T., Bampton, P. A., Bitton, A., Boucher, G., Brand, S., Buening, C., Cohain, A., Cichon, S., D'Amato, M., De Jong, D., Devaney, K. L., Dubinsky, M., Edwards, C., Ellinghaus, D., Ferguson, L. R., Franchimont, D., Fransen, K., Gearry, R., Georges, M., Gieger, C., Glas, J., Haritunians, T., Wijmenga, C. & Int IBD Genetics Consortium IIBDGC, 1-nov.-2012, In: Nature. 491, 7422, blz. 119-124 6 blz.

  Onderzoeksoutput: Article › Academic › peer review

  • Microorganism 100%
  • Genetic Architecture 100%
  • Allele 100%
  • Inflammatory Bowel Disease 100%
  • Autophagy 50%
  3866 Citaten (Scopus)

• Limited Evidence for Parent-of-Origin Effects in Inflammatory Bowel Disease Associated Loci

  Fransen, K., Mitrovic, M., van Diemen, C. C., Thelma, B. K., Sood, A., Franke, A., Schreiber, S., Midha, V., Juyal, G., Potocnik, U., Fu, J., Nolte, I. & Weersma, R. K., 27-sep.-2012, In: PLoS ONE. 7, 9, 8 blz., e45287.

  Onderzoeksoutput: Article › Academic › peer review

  Open Access

  Bestand

  • NOD2 100%
  • Genomic Imprinting 100%
  • Genome-Wide Association Study 50%
  • Genetic Determinism 50%
  • Genetic Risk 50%
  8 Citaten (Scopus)

  224 Downloads (Pure)
• 2011

  Association of the protein-tyrosine phosphatase nonreceptor type substrate 1 (PTPNS1) gene with inflammatory bowel disease

  Roberts, R. L., Hollis-Moffatt, J. E., Gómez-García, M., Fransen, K., Ponsioen, C. Y., Crusius, B. A., Wijmenga, C., Martín, J., Weersma, R. K., Merriman, T. R., Barclay, M. L., Gearry, R. B. & Alizadeh, B. Z., 1-feb.-2011, In: Inflammatory Bowel Diseases. 17, 2, blz. E19-21 3 blz.

  Onderzoeksoutput: Article › Academic › peer review

• Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

  Trynka, G., Hunt, K. A., Bockett, N. A., Romanos, J., Mistry, V., Szperl, A., Bakker, S. F., Bardella, M. T., Bhaw-Rosun, L., Castillejo, G., de la Concha, E. G., de Almeida, R. C., Dias, K.-R. M., van Diemen, C. C., Dubois, P. C. A., Duerr, R. H., Edkins, S., Franke, L., Fransen, K. & Gutierrez, J. & 33 anderen, Heap, G. A. R., Hrdlickova, B., Hunt, S., Plaza Izurieta, L., Izzo, V., Joosten, L. A. B., Langford, C., Mazzilli, M. C., Mein, C. A., Midah, V., Mitrovic, M., Mora, B., Morelli, M., Nutland, S., Nunez, C., Onengut-Gumuscu, S., Pearce, K., Platteel, M., Polanco, I., Potter, S., Ribes-Koninckx, C., Ricano-Ponce, I., Rich, S. S., Rybak, A., Luis Santiago, J., Senapati, S., Sood, A., Szajewska, H., Zhernakova, A., Wijmenga, C., Spanish Consortium Genetics Coelia, PreventCD Study Grp & WTCCC, dec.-2011, In: Nature Genetics. 43, 12, blz. 1193-U45 10 blz.

  Onderzoeksoutput: Article › Academic › peer review

  • Genotyping 100%
  • Rare Variant Association Study 100%
  • Genetic Architecture 50%
  • Genetic Divergence 50%
  • Gene Linkage Disequilibrium 50%
  670 Citaten (Scopus)

• Differential Association of Two PTPN22 Coding Variants with Crohn's Disease and Ulcerative Colitis

  Diaz-Gallo, L.-M., Espino-Paisan, L., Fransen, K., Gomez-Garcia, M., van Sommeren, S., Cardena, C., Rodrigo, L., Mendoza, J. L., Taxonera, C., Nieto, A., Alcain, G., Cueto, I., Lopez-Nevot, M. A., Bottini, N., Barclay, M. L., Crusius, J. B., van Bodegraven, A. A., Wijmenga, C., Ponsioen, C. Y. & Gearry, R. B. & 6 anderen, Roberts, R. L., Weersma, R. K., Urcelay, E., Merriman, T. R., Alizadeh, B. Z. & Martin, J., nov.-2011, In: Inflammatory Bowel Diseases. 17, 11, blz. 2287-2294 8 blz.

  Onderzoeksoutput: Article › Academic › peer review

  • PTPN22 100%
  • PTPN22 Gene 83%
  • Autoimmunity 25%
  • Allele 25%
  • SNP Assay 16%
  77 Citaten (Scopus)
• 2010

  Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease

  Fransen, K., Visschedijk, M. C., van Sommeren, S., Fu, J. Y., Franke, L., Festen, E. A. M., Stokkers, P. C. F., van Bodegraven, A. A., Crusius, J. B. A., Hommes, D. W., Zanen, P., de Jong, D. J., Wijmenga, C., van Diemen, C. C. & Weersma, R. K., 1-sep.-2010, In: Human Molecular Genetics. 19, 17, blz. 3482-3488 7 blz.

  Onderzoeksoutput: Article › Academic › peer review

  • Gene Expression 100%
  • Single Nucleotide Polymorphism 100%
  • Boron Trichloride 100%
  • UBE2L3 100%
  • Expression Quantitative Trait Loci 71%
  91 Citaten (Scopus)