Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Persoonlijk profiel
Speerpunten
Applied Research Activities
Structure-based drug design in human diseases
Basic Research Activities
Structural, biochemical and molecular biology investigation of malarial pathways:
Carbon metabolism in P falciparum
Vitamin biosynthesis in P. falciparum
Method Developments
Crystal identification for structural biology
Biological imaging on free-electron lasers
Netwerk
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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Structural characterization and extended substrate scope analysis of two Mg<sup>2+</sup>-dependent O-methyltransferases from bacteria
Sokolova, N., Zhang, L., Deravi, S., Oerlemans, R., Groves, M. R. & Haslinger, K., 29-jan.-2023, (Submitted) BioRxiv, 17 blz.Onderzoeksoutput: Voordruk › Academic
Bestand11 Downloads (Pure) -
Actionability of on-target ALK Resistance Mutations in Patients With Non-Small Cell Lung Cancer: Local Experience and Review of the Literature
Koopman, B., Groen, H. J. M., Schuuring, E., Hiltermann, J., Timens, W., den Dunnen, W. F. A., van den Berg, A., ter Elst, A., van Kruchten, M., Kluiver, J., Hiddinga, B., Hijmering-Kappelle, L., Groves, M., Vilachá Madeira R Santos, J., van Kempen, L. & van der Wekken, A. J., mrt.-2022, In: Clinical lung cancer. 23, 2, blz. e104-e115 12 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand4 Citaten (Scopus)50 Downloads (Pure) -
Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders
Ulgheri, F., Spanu, P., Deligia, F., Loriga, G., Fuggetta, M. P., de Haan, I., Chandgudge, A., Groves, M. & Domling, A., 5-feb.-2022, In: European Journal of Medicinal Chemistry. 229, 114002.Onderzoeksoutput › Academic › peer review
Open AccessBestand2 Citaten (Scopus)21 Downloads (Pure) -
Discovery of Small-Molecule Allosteric Inhibitors of PfATC as Antimalarials
Wang, C., Zhang, B., Krüger, A., Du, X., Visser, L., Dömling, A., Wrenger, C. & Groves, M., 19-okt.-2022, In: Journal of the American Chemical Society. 144, 41, blz. 19070–19077 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand23 Downloads (Pure) -
Engineering a plant polyketide synthase for the biosynthesis of methylated flavonoids
Peng, B., Zhang, L., He, S., Oerlemans, R., Quax, W. J., Groves, M. R. & Haslinger, K., 2-okt.-2022, (Submitted) BioRxiv, 27 blz.Onderzoeksoutput: Voordruk › Academic
Bestand5 Downloads (Pure)
Activiteiten
- 1 Organising and contributing to an event
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Pharmacy Day 2018
Anna Salvati (Organiser), Amalia Dolga (Organiser), Matthew Groves (Organiser), Klaus Mathwig (Organiser), Peter Horvatovich (Organiser), Wim J. Quax (Organiser), Anne Lexmond (Organiser) & Gillian Dempsey (Organiser)
12-jun.-2018Activiteit: Organising and contributing to an event › Academic