Peter Olinga

2018

Pharmacokinetics of a sustained release formulation of PDGFβ-receptor directed carrier proteins to target the fibrotic liver

van Dijk, F., Teekamp, N., Beljaars, L., Post, E., Zuidema, J., Steendam, R., Kim, Y. O., Frijlink, H. W., Schuppand, D., Poelstra, K., Hinrichs, W. L. J. & Olinga, P., 10-jan.-2018, In: Journal of Controlled Release. 269, blz. 258-265 8 blz.

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26 Citaten (Scopus)

377 Downloads (Pure)

Real-time monitoring of biliary transport in precision-cut liver slices

Grajewski, M., Salentijn, G. I. J., Karsten, R. E. H., Olinga, P. & Verpoorte, E., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society , blz. 1644-1646 3 blz. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 3).

Onderzoeksoutput › Academic › peer review

Regional Differences in Intestinal Drug Metabolism

Iswandana, R., Irianti, M. I., Oosterhuis, D., Hofker, H. S., Merema, M. T., de Jager, M. H., Mutsaers, H. A. & Olinga, P., dec.-2018, In: Drug Metabolism and Disposition. 46, 11, blz. 1879-1885

Onderzoeksoutput: Article › Academic › peer review

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12 Citaten (Scopus)

78 Downloads (Pure)

siRNA-mediated protein knockdown in precision-cut lung slices

Ruigrok, M., Xian, J. L., Frijlink, H. W., Melgert, B., Hinrichs, W. & Olinga, P., 2018.

Onderzoeksoutput › Academic

siRNA-mediated protein knockdown in precision-cut lung slices

Ruigrok, M. J. R., Xian, J.-L., Frijlink, H. W., Melgert, B. N., Hinrichs, W. L. J. & Olinga, P., dec.-2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, blz. 339-348

Onderzoeksoutput › Academic › peer review

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22 Citaten (Scopus)

313 Downloads (Pure)

siRNA-mediated RNA interference in precision-cut tissue slices prepared from mouse lung

Ruigrok, M., Maggan, N., Frijlink, H. W., Melgert, B., Olinga, P. & Hinrichs, W., 2018.

Onderzoeksoutput › Academic

1 Downloads (Pure)

Targeting Oxidative Stress for the Treatment of Liver Fibrosis

Luangmonkong, T., Suriguga, S., Mutsaers, H. A. M., Groothuis, G. M. M., Olinga, P. & Boersema, M., 2018, Reviews of Physiology, Biochemistry and Pharmacology. Nilius, B., DeTombe, P., Gudermann, T., Jahn, R. & Lill, R. (uitgave). Cham: Springer-Verlag Berlin Heidelberg, blz. 71-102 32 blz. (Reviews of Physiology Biochemistry and Pharmacology; vol. 175).

Onderzoeksoutput: Chapter › Academic › peer review

213 Citaten (Scopus)

2017

Addition of Pullulan to Trehalose Glasses Improves the Stability of β-Galactosidase at High Moisture Conditions

Teekamp, N., Tian, Y., Visser, J. C., Olinga, P., Frijlink, H. W., Woerdenbag, H. J. & Hinrichs, W. L. J., 15-nov.-2017, In: Carbohydrate Polymers. 176, blz. 374-380 7 blz.

Onderzoeksoutput: Article › Academic › peer review

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33 Citaten (Scopus)

494 Downloads (Pure)

A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages

Boorsma, C. E., van der Veen, T. A., Putri, K. S. S., de Almeida, A., Draijer, C., Mauad, T., Fejer, G., Brandsma, C.-A., van den Berge, M., Bossé, Y., Sin, D., Hao, K., Reithmeier, A., Andersson, G., Olinga, P., Timens, W., Casini, A. & Melgert, B. N., 3-okt.-2017, In: Scientific Reports. 7, 1, 14 blz., 12570.

Onderzoeksoutput: Article › Academic › peer review

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16 Citaten (Scopus)

333 Downloads (Pure)

Early suppression of the serological macrophage activity biomarker VICM, and not suppression of CRP, predicts the response to infliximab in Crohn's disease patients

Mortensen, J. H., van Haaften, W. T., Olesen, M. L., Karsdal, M., Olinga, P., Dijkstra, G. & Bay-Jensen, A.-C., 1-feb.-2017, In: Journal of Crohn's and Colitis. 11, blz. S423-S424 2 blz.

Onderzoeksoutput › Academic

Evaluating the antifibrotic potency of galunisertib in a human ex vivo model of liver fibrosis

Luangmonkong, T., Suriguga, S., Bigaeva, E., Boersema, M., Oosterhuis, D., de Jong, K. P., Schuppan, D., Mutsaers, H. A. M. & Olinga, P., sep.-2017, In: British Journal of Pharmacology. 174, 18, blz. 3107-3117 11 blz.

Onderzoeksoutput: Article › Academic › peer review

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72 Citaten (Scopus)

77 Downloads (Pure)

Hepcidin is an HDAC3 regulated gene and its expression is determined by promoter-associated histone acetylation

Pasricha, S.-R., Lim, P. J., Duarte, T., Casu, C., Mleczko-Sanecka, K., Suciu, M., Areas, J., Da Silva, A. R., Frost, J., McHugh, K., Porto, G., Draper, S., Gooding, S., Olinga, P., Muckenthaler, M., Rivella, S., Hughes, J., Milne, T., Armitage, A. & Drakesmith, H., aug.-2017, In: American Journal of Hematology. 92, 8, blz. E351-E351 1 blz.

Onderzoeksoutput › Academic

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

Pasricha, S.-R., Lim, P. J., Duarte, T. L., Casu, C., Oosterhuis, D., Mleczko-Sanecka, K., Suciu, M., Da Silva, A. R., Al-Hourani, K., Arezes, J., McHugh, K., Gooding, S., Frost, J. N., Wray, K., Santos, A., Porto, G., Repapi, E., Gray, N., Draper, S. J. & Ashley, N. & 8 anderen, Soilleux, E., Olinga, P., Muckenthaler, M. U., Hughes, J. R., Rivella, S., Milne, T. A., Armitage, A. E. & Drakesmith, H., 1-sep.-2017, In: Nature Communications. 8, 15 blz., 403.

Onderzoeksoutput › Academic › peer review

Open Access

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50 Citaten (Scopus)

459 Downloads (Pure)

Inhibition of toll-like receptor 9 by ODN-2088 reduces inflammation in murine precision-cut liver slices

Suriguga, S., Mutsaers, H., Groothuis, G. & Olinga, P., 1-okt.-2017, blz. 149-1185.

Onderzoeksoutput › Academic

Misbalance in type III collagen formation/degradation as a novel serological biomarker for penetrating (Montreal B3) Crohn's disease

van Haaften, W. T., Mortensen, J. H., Karsdal, M. A., Bay-Jensen, A. C., Dijkstra, G. & Olinga, P., jul.-2017, In: Alimentary Pharmacology & Therapeutics. 46, 1, blz. 26-39 14 blz.

Onderzoeksoutput: Article › Academic › peer review

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48 Citaten (Scopus)

349 Downloads (Pure)

Murine Precision-Cut Kidney Slices as an ex vivo Model to Evaluate the Role of Transforming Growth Factor-β1 Signaling in the Onset of Renal Fibrosis

Stribos, E. G. D., Seelen, M. A., van Goor, H., Olinga, P. & Mutsaers, H. A. M., 12-dec.-2017, In: Frontiers in Physiology. 8, 9 blz., 1026.

Onderzoeksoutput: Article › Academic › peer review

Open Access

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23 Citaten (Scopus)

364 Downloads (Pure)

Non-invasive quantification of collagen turnover in renal transplant recipients

Stribos, E. G. D., Nielsen, S. H., Brix, S., Karsdal, M. A., Seelen, M. A., van Goor, H., Bakker, S. J. L., Olinga, P., Mutsaers, H. A. M. & Genovese, F., 21-apr.-2017, In: PLoS ONE. 12, 4, 11 blz., e0175898.

Onderzoeksoutput: Article › Academic › peer review

Open Access

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31 Citaten (Scopus)

373 Downloads (Pure)

PI3K/MTOR PATHWAY INHIBITION IN EX-VIVO LIVER MODEL

Gore, E., Bigaeva, E., Boersema, M., Nicklin, P., Schuppan, D. & Olinga, P., apr.-2017, In: Gastroenterology. 152, 5, blz. S1105-S1105 1 blz.

Onderzoeksoutput › Academic

Polymeric microspheres for the sustained release of a protein-based drug carrier targeting the PDGFβ-receptor in the fibrotic kidney

Teekamp, N., Van Dijk, F., Broesder, A., Evers, M., Zuidema, J., Steendam, R., Post, E., Hillebrands, J. L., Frijlink, H. W., Poelstra, K., Beljaars, L., Olinga, P. & Hinrichs, W. L. J., 20-dec.-2017, In: International Journal of Pharmaceutics. 534, 1-2, blz. 229-236 8 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

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24 Citaten (Scopus)

456 Downloads (Pure)

Precision-cut bile duct slices as a model to study regeneration of bile ducts of human donor livers after ischemic preservation injury

de Jong, I. E. M., Matton, A., Suriguga, S., van Praagh, J., van Haaften, W., Wiersema-Buist, J., Iswandana, R., Oosterhuis, D., Gouw, A. S. H., Lisman, J., Olinga, P. & Porte, R., 10-jun.-2017, blz. 187-188. 230 blz.

Onderzoeksoutput › Academic

Serological biomarkers of tissue turnover can early identify responders to infliximab in Crohn's disease

van Haaften, W. T., Mortensen, J. H., Olesen, M. L., Karsdal, M. A., Olinga, P., Bay-Jensen, A.-C. & Dijkstra, G., 1-feb.-2017, In: Journal of Crohn's and Colitis. 11, blz. S57-S57 1 blz.

Onderzoeksoutput › Academic

siRNA-mediated RNA interference in precision-cut tissue slices prepared from mouse lung and kidney

Ruigrok, M. J. R., Maggan, N., Willaert, D., Frijlink, H. W., Melgert, B. N., Olinga, P. & Hinrichs, W. L. J., nov.-2017, In: The AAPS Journal. 19, 6, blz. 1855-1863 9 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

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20 Citaten (Scopus)

411 Downloads (Pure)

Studying Non-Alcoholic Fatty Liver Disease: Development of an Ex Vivo Model

Prins, G., Luangmonkong, T., Weymaere, J., Suriguga, S., Oosterhuis, D., Schuppan, D., Mutsaers, H. & Olinga, P., jul.-2017, blz. 19-20.

Onderzoeksoutput › Academic

Therapeutic proteins in the treatment of liver fibrosis: The antifibrotic potential of a sustained release formulation for a PDGF beta-receptor targeted rho-kinase inhibitor

van Dijk, F., Teekamp, N., Beljaars, L., Post, E., Kim, Y. O., Frijlink, E., Hinrichs, W., Schuppan, D., Poelstra, K. & Olinga, P., okt.-2017, In: Hepatology. 66, blz. 217A 1 blz.

Onderzoeksoutput › Academic

Towards clinical use of targeted therapies for liver fibrosis: development of a sustained release formulation for therapeutic proteins

Van Dijk, F., Teekamp, N., Beljaars, L., Post, E., Schuppan, D., Kim, Y. O., Poelstra, K., Frijlink, E., Hinrichs, W. & Olinga, P., 2017, In: Journal of Hepatology. 66, 1, blz. S44-S44 1 blz.

Onderzoeksoutput › Academic

Validation of precision-cut liver slices to study drug-induced cholestasis: A transcriptomics approach

Vatakuti, S., Olinga, P., Pennings, J. L. A. & Groothuis, G. M. M., mrt.-2017, In: Archives of toxicology. 91, 3, blz. 1401-1412 12 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

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33 Citaten (Scopus)

380 Downloads (Pure)

2016

Biodegradable microspheres for the sustained release of PDGF-receptor directed pPB-HSA targeted to the fibrotic kidney

Teekamp, N., van Dijk, F., Beljaars, E., Hinrichs, W., Steendam, R., Zuidema, J., Poelstra, K., Frijlink, H. W. & Olinga, P., 2016.

Onderzoeksoutput › Academic

Biodegradable microspheres for the sustained release of PDGF-receptor directed PPB-HSA targeted to the fibrotic kidney

Teekamp, N., van Dijk, F., Beljaars, E., Hinrichs, W., Poelstra, K., Frijlink, H. W. & Olinga, P., 2016.

Onderzoeksoutput › Academic

Bestand

143 Downloads (Pure)

Biodegradable microspheres for the sustained release of ppB-HSA to target PDGFβ-receptors in fibrotic tissues

Teekamp, N., van Dijk, F., Beljaars, E., Post, E., Hinrichs, W., Poelstra, K. & Olinga, P., 2016.

Onderzoeksoutput › Academic

Bestand

111 Downloads (Pure)

Classification of cholestatic and necrotic hepatotoxicants using transcriptomics on human precision-cut liver slices

Vatakuti, S., Pennings, J. L. A., Gore, E., Olinga, P. & Groothuis, G. M. M., 16-feb.-2016, In: Chemical research in toxicology. 29, 3, blz. 342-351 10 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

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22 Citaten (Scopus)

155 Downloads (Pure)

Dissecting the molecular antifibrotic effect of the TGF-Beta(I) receptor kinase inhibitor galunisertib in precision-cut liver slices

Luangmonkong, T., Suriguga, S., Bigaeva, E., Oosterhuis, D., de Jong, K., Schuppan, D., Mutsaers, H. & Olinga, P., 2016, In: Journal of Hepatology. 64, blz. S713-S714 2 blz.

Onderzoeksoutput › Academic

Human precision-cut liver slices as a model to test antifibrotic drugs in the early onset of liver fibrosis

Westra, I. M., Mutsaers, H. A. M., Luangmonkong, T., Hadi, M., Oosterhuis, D., de Jong, K. P., Groothuis, G. M. M. & Olinga, P., sep.-2016, In: Toxicology in Vitro. 35, blz. 77-85 9 blz.

Onderzoeksoutput: Article › Academic › peer review

55 Citaten (Scopus)

Intestinal microbiota and anastomotic leakage of stapled colorectal anastomoses: a pilot study

van Praagh, J. B., de Goffau, M. C., Bakker, I. S., Harmsen, H. J. M., Olinga, P. & Havenga, K., jun.-2016, In: Surgical endoscopy and other interventional techniques. 30, 6, blz. 2259-2265 7 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

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68 Citaten (Scopus)

404 Downloads (Pure)

LPS aggravates fibrosis only in the early onset but not in the end stage of liver fibrosis

Suriguga, S., Luangmonkong, T., Bigaeva, E., Oosterhuis, D., Mutsaers, H. A., Groothuis, G. M. & Olinga, P., 1-okt.-2016, In: Hepatology. 64, S1, blz. 840A

Onderzoeksoutput › Academic

Open Access

Bestand

266 Downloads (Pure)

Open Access

Bestand

35 Citaten (Scopus)

134 Downloads (Pure)

Organ Fibrosis: Triggers, Pathways, and Cellular Plasticity

Mutsaers, H. A. M. & Olinga, P., 15-nov.-2016, In: Frontiers in Medicine. 3, 2 blz., 55.

Onderzoeksoutput: Editorial › Academic › peer review

Open Access

Bestand

20 Citaten (Scopus)

271 Downloads (Pure)

Pathophysiologic model of non-alcoholic fatty liver disease using precision-cut liver slices

Luangmonkong, T., Weymaere, J., Suriguga, S., Oosterhuis, D., Schuppan, D., Mutsaers, H. A. & Olinga, P., okt.-2016, In: Hepatology. 64, S1, blz. 786A 1 blz.

Onderzoeksoutput › Academic

Open Access

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356 Downloads (Pure)

Precision-Cut Human Kidney Slices as a Model to Elucidate the Pathogenesis of Renal Fibrosis

Stribos, E., Luangmonkong, T., Kors, A., de Jong, I., van Son, W., Hillebrands, J.-L., Seelen, M., van Goor, H., Olinga, P. & Mutsaers, H., 7-nov.-2016, blz. 733-733. 1 blz.

Onderzoeksoutput › Academic

Precision-cut human kidney slices as a model to elucidate the process of renal fibrosis

Stribos, E. G. D., Luangmonkong, T., Leliveld, A. M., de Jong, I. J., van Son, W. J., Hillebrands, J.-L., Seelen, M. A., van Goor, H., Olinga, P. & Mutsaers, H. A. M., apr.-2016, In: Translational Research. 170, blz. 8-16 9 blz.

Onderzoeksoutput: Article › Academic › peer review

42 Citaten (Scopus)

Renal fibrosis in precision-cut kidney slices

Stribos, E. G. D., Hillebrands, J.-L., Olinga, P. & Mutsaers, H. A. M., 5-nov.-2016, In: European Journal of Pharmacology. 790, blz. 57-61 5 blz.

Onderzoeksoutput: Article › Academic › peer review

27 Citaten (Scopus)

2015

Acute toxicity of CCl4 but not of paracetamol induces a transcriptomic signature of fibrosis in precision-cut liver slices

Vatakuti, S., Schoonen, W. G. E. J., Elferink, M., Groothuis, G. M. M. & Olinga, P., aug.-2015, In: Toxicology in Vitro. 29, 5, blz. 1012-1020 9 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

24 Citaten (Scopus)

93 Downloads (Pure)

Chronic Kidney Disease and Fibrosis: The Role of Uremic Retention Solutes

Mutsaers, H. A. M., Stribos, E. G. D., Glorieux, G., Vanholder, R. & Olinga, P., 31-aug.-2015, In: Frontiers in Medicine. 2, 7 blz., 60.

Onderzoeksoutput › Professional

Open Access

Bestand

61 Citaten (Scopus)

323 Downloads (Pure)

Classification of hepatotoxicity due to cholestasis and necrosis using transcriptomics on human precision-cut liver slices

Vatakuti, S., Olinga, P., Pennings, J. L. & Groothuis, G., 2015, In: The Toxicologist. Late-Breaking Supplement, blz. 173-174 2 blz., Abstract No. 2796.

Onderzoeksoutput › Academic

Evaluating the efficacy of potential drugs for intestinal fibrosis using precision-cut tissue slices

Iswandana, R., Pham, B. T., van Haaften, W., Oosterhuis, D., Mutsaers, H. & Olinga, P., 1-feb.-2015, In: Journal of Crohn's and Colitis. 9, suppl 1, blz. s116 1 blz.

Onderzoeksoutput › Academic

Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn's Disease from Ulcerative Colitis

Mortensen, J. H., Godskesen, L. E., Jensen, M. D., Van Haaften, W. T., Klinge, L. G., Olinga, P., Dijkstra, G., Kjeldsen, J., Karsdal, M. A., Bay-Jensen, A.-C. & Krag, A., okt.-2015, In: Journal of Crohn's and Colitis. 9, 10, blz. 863-872 10 blz.

Onderzoeksoutput: Article › Academic › peer review

Open Access

Bestand

72 Citaten (Scopus)

43 Downloads (Pure)

Open Access

Bestand

42 Citaten (Scopus)

598 Downloads (Pure)

Peter Olinga

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