Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Persoonlijk profiel
Speerpunten
My practical and theoretical background enables me to take an integrative omics approach to identify driver genetic alterations, genes and biological pathways that are relevant for the pathophysiological behaviour and treatment response of tumors and rapidly translate these findings to clinical practice.
In addition to my training as a medical doctor, I completed one full year of Mathematics and Computer Science, after which I continued to obtain my MSc degree in Cognitive Science and Engineering.
In parallel to my medical studies, I worked for several years as a bio-informatician at the Department of Genetics, UMCG. In 2010, I obtained my PhD on high dimensional data analysis for new insights into ovarian cancer phenotypes, after which I continued as an affiliated post-doc at the Departments of Genetics and Medical Oncology (UMCG).
I followed the residency program in Internal Medicine / Medical Oncology and now work as a medical oncologist (staff member) at the department of Medical Oncology at the UMCG. In addition, I am a principal investigator at the Cancer Research Center Groningen in the research programmes: ‘Guided Treatment in Optimal Selected Cancer Patients (GUTS)’ and ‘Damage and Repair in Cancer Development and Cancer (DARE)’.
Expertise gerelateerd aan duurzame ontwikkelingsdoelstellingen van de VN
In 2015 stemden de VN-lidstaten in met 17 wereldwijde duurzame ontwikkelingsdoelstellingen (Sustainable Development Goals, SDG's) om armoede te beëindigen, de planeet te beschermen en voor iedereen welvaart te garanderen. Het werk van deze persoon draagt bij aan de volgende duurzame ontwikkelingsdoelstelling(en):
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Rudolf Fehrmann actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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Cyclin E1 overexpression triggers interferon signaling and is associated with antitumor immunity in breast cancer
Yu, S., Stappenbelt, C., Chen, M., Dekker, M., Bhattacharya, A., van der Sluis, T., Zwager, M. C., Schröder, C. P., Fehrmann, R. S. N., van Vugt, M. A. T. M. & van der Vegt, B., 17-mrt.-2025, In: Journal for immunotherapy of cancer. 13, 3, 12 blz., e009239.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand -
128P - Whole blood transcriptomics identifies transcriptional patterns linked to outcomes in patients receiving immune checkpoint inhibitors
Hone Lopez, S., Loipfinger, S., Bhattacharya, A., Jalving, M., Oosting, S. F., Hiltermann, J., de Bruyn, M., de Vries, E. G. E., de Haan, J.-J. & Fehrmann, R., 14-sep.-2024, In: Annals of Oncology. 35, Supplement 2, blz. S266 1 blz.Onderzoeksoutput › Academic
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Exploring combinations of dimensionality reduction, transfer learning, and regularization methods for predicting binary phenotypes with transcriptomic data
Oshternian, S. R., Loipfinger, S., Bhattacharya, A. & Fehrmann, R. S. N., 26-apr.-2024, In: Bmc Bioinformatics. 25, 19 blz., 167.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand2 Citaten (Scopus)57 Downloads (Pure) -
Functional ex vivo DNA fibre assay to measure replication dynamics in breast cancer tissue
Chen, M., van den Tempel, N., Bhattacharya, A., Yu, S., Rutgers, B., Fehrmann, R. S. N., de Haas, S., van der Vegt, B. & van Vugt, M. A. T. M., sep.-2024, In: Journal of Pathology. 264, 1, blz. 90-100 11 blz.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand1 Citaat (Scopus)64 Downloads (Pure) -
Identification of new head and neck squamous cell carcinoma molecular imaging targets
van Schaik, J. E., van der Vegt, B., Slagter-Menkema, L., van der Laan, B. F. A. M., Witjes, M. J. H., Oosting, S. F., Fehrmann, R. S. N. & Plaat, B. E. C., apr.-2024, In: Oral Oncology. 151, 7 blz., 106736.Onderzoeksoutput: Article › Academic › peer review
Open AccessBestand60 Downloads (Pure)
Activiteiten
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Dutch Cancer Society (KWF Kankerbestrijding) (Externe Organisatie)
Fehrmann, R. (Member)
2024 → …Activiteit: Membership › Professional
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Using machine learning to unravel the 'cancer-immune setpoint' in rare cancers (SETPOINT)
Fehrmann, R. (Invited speaker)
26-nov.-2024Activiteit: Professional or public presentation › Professional
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Deciphering the Role of Leukocytes in Sepsis-Induced Acute Lung Injury: Pathogenesis, Biomarkers, and Therapeutic Implications.
Fehrmann, R. (Supervisor)
2024 → …Activiteit: Supervision and examination of PhD students of the UG › Academic
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Novel AI-enabled strategies in biomarker-informed clinical trials
Fehrmann, R. (Invited speaker)
15-sep.-2024Activiteit: Professional or public presentation › Professional
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ESMO Precision Oncology Working Group (Externe Organisatie)
Fehrmann, R. (Member)
13-dec.-2024 → …Activiteit: Membership › Professional
Datasets
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Data to: Evidence Based Selection of Housekeeping Genes
de Jonge, H. (Creator), Fehrmann, R. (Creator), de Bont, E. (Creator), Hofstra, R. M. W. (Creator), Gerbens, F. (Creator), Kamps, W. (Creator), de Vries, E. G. E. (Creator), van der Zee, A. (Creator), te Meerman, G. (Creator) & ter Elst, A. (Creator), University of Groningen, 19-sep.-2007
https://figshare.com/articles/Evidence_Based_Selection_of_Housekeeping_Genes/151673
Dataset
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Additional file 2 of Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma
Visconti, A. (Creator), Rossi, N. (Creator), Deriš, H. (Creator), Lee, K. A. (Creator), Hanić, M. (Creator), Trbojević-Akmačić, I. (Creator), Thomas, A. M. (Creator), Bolte, L. (Creator), Björk, J. (Creator), Hooiveld-Noeken, J. (Creator), Board, R. (Creator), Harland, M. (Creator), Newton-Bishop, J. (Creator), Harries, M. (Creator), Sacco, J. J. (Creator), Lorigan, P. (Creator), Shaw, H. M. (Creator), de Vries, L. (Creator), Fehrmann, R. S. N. (Creator), Weersma, R. K. (Creator), Spector, T. D. (Creator), Nathan, P. (Creator), Hospers, G. A. P. (Creator), Sasieni, P. (Creator), Bataille, V. (Creator), Lauc, G. (Creator) & Falchi, M. (Creator), figshare, 18-feb.-2023
DOI: 10.6084/m9.figshare.22613744.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Total_serum_N-glycans_associate_with_response_to_immune_checkpoint_inhibition_therapy_and_survival_in_patients_with_advanced_melanoma/22613744/1
Dataset
Knipsels
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KWF-subsidie voor onderzoek naar werking immuuntherapie bij triple-negatieve borstkanker
22/07/2022 → 25/07/2022
3 items van Media-aandacht
Pers / media: Expert Comment › Popular
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UMCG krijgt miljoen euro voor onderzoek naar therapie bij agressieve borstkanker
22/07/2022
1 Mediabijdrage
Pers / media: Expert Comment › Popular
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UMCG krijgt miljoen euro voor onderzoek naar therapie bij agressieve borstkanker
22/07/2022
1 item van Media-aandacht
Pers / media: Expert Comment › Popular
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Prangende vragen én antwoorden over artificial intelligence in de zorg
02/09/2021
1 item van Media-aandacht
Pers / media: Expert Comment › Professional
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Artificial Intelligence in Medical Oncology
02/09/2021
1 Mediabijdrage
Pers / media: Expert Comment › Professional
Prijzen
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Selected for the J.W.R. Nortier lecture
Fehrmann, R. (Recipient), 11-apr.-2013
Prijs: National/international honour › Academic
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