Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Persoonlijk profiel
Speerpunten
Curriculum Vitae
Sophia Bruggeman (The Netherlands, 1979) studied Biology at the University of Nijmegen. As PhD student, she worked at the Netherlands Cancer Institute on the role of Polycomb group genes in brain development and cancer (2008, cum laude). She next moved to King's College London to work on the development of the chick and zebrafish forebrain on a KWF postdoctoral fellowship. This fellowship was completed at the European Research Institute for the Biology of Ageing (ERIBA/University Medical Center Groningen).
After awardance of a Rosalind Franklin fellowship (tenure track position) and a KWF Cancer Research career award, Sophia started her own research group at the department of Pediatric Oncology and Hematology/Pediatrics, UMCG (2014). In 2019, Sophia's research group moved to ERIBA, UMCG. Her research aims at understaning how normal neurodevelopmental processes influence pediatric brain cancer initiation and progression.
Netwerk
Recente externe samenwerking op landenniveau. Duik in de details door op de stippen te klikken.
Onderzoeksoutput
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Heat Shock Factor 1 (HSF1-pSer326) Predicts Response to Bortezomib-Containing Chemotherapy in Pediatric AML: A COG Study
Hoff, F. W., van Dijk, A. D., Qiu, Y. H., Ruvolo, P. P., Gerbing, R. B., Leonti, A. R., Jenkins, G. N., Gamis, A. S., Aplenc, R., Kolb, E. A., Alonzo, T., Meshinchi, S., De Bont, E., Bruggeman, S. W., Kornblau, S. M. & Horton, T. M., 25-feb-2021, In: Blood. 137, blz. 1050-1060 11 blz.Onderzoeksoutput › Academic › peer review
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Loss of H3K27 Methylation Identifies Poor Outcome in Adult-Onset Acute Myeloid Leukemia
van Dijk, A. D., Hoff, F. W., Qiu, Y., de Bont, E. S., Bruggeman, S. W. M., Horton, T. M. & Kornblau, S. M., 5-nov-2020, In: Blood. 136, 3 blz.Onderzoeksoutput › Academic
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The developmental stage of the medulloblastoma cell-of-origin is maintained in cancer and restricts hedgehog pathway usage and drug sensitivity
Smit, M., Armandari, I., Bockaj, I., Martini, T., Zomerman, W., Siragna, Z., Meeuwsen-de Boer, T., Scherpen, F., Schoots, M., Ritsema, M., den Dunnen, W., Hoving, E., Paridaen, J., de Haan, G., Guryev, V. & Bruggeman, S., apr-2019, In: Neuro-Oncology. 21, blz. 104 1 blz.Onderzoeksoutput › Academic
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Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma
Zomerman, W. W., Plasschaert, S. L. A., Conroy, S., Scherpen, F. J., Meeuwsen-de Boer, T. G. J., Lourens, H. J., Guerrero Llobet, S., Smit, M. J., Slagter-Menkema, L., Seitz, A., Gidding, C. E. M., Hulleman, E., Wesseling, P., Meijer, L., van Kempen, L. C., van den Berg, A., Warmerdam, D. O., Kruyt, F. A. E., Foijer, F., van Vugt, M. A. T. M. & 5 anderen, , 20-mrt-2018, In: Cell reports. 22, 12, blz. 3206-3216 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand -
IDENTIFICATION OF TWO PROTEIN-SIGNALING STATES DELINEATING TRANSCRIPTIONALLY HETEROGENEOUS HUMAN MEDULLOBLASTOMA
Zomerman, W., Plasschaert, S., Conroy, S., Scherpen, F., Meeuwsen-de Boer, T., Lourens, H-J., Llobet, S. G., Smit, M., Slagter-Menkema, L., Seitz, A., Gidding, C., Hulleman, E., Wesseling, P., Meijer, L., van Kempen, L., van den Berg, A., Warmerdam, D., Kruyt, F., Foijer, F., van Vugt, M. & 5 anderen, , jun-2018, In: Neuro-Oncology. 20, blz. 136-136 1 blz.Onderzoeksoutput › Academic
Activiteiten
- 1 Visiting an external institution
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Princess Maxima Ctr Paediat Oncol
Sophia Bruggeman (Visiting researcher)
19-dec-2017Activiteit: Visiting an external institution › Academic
Prijzen
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Differential drug sensitivity in pediatric brain cancer precursor cells: towards tailored treatments for infant and childhood medulloblastoma.
Bruggeman, Sophia (Recipient), 19-jul-2018
Prijs: Fellowship awarded competitively › Academic