Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Persoonlijk profiel
Speerpunten
Curriculum Vitae
Sophia Bruggeman (The Netherlands, 1979) studied Biology at the University of Nijmegen. As PhD student, she worked at the Netherlands Cancer Institute on the role of Polycomb group genes in brain development and cancer (2008, cum laude). She next moved to King's College London to work on the development of the chick and zebrafish forebrain on a KWF postdoctoral fellowship. This fellowship was completed at the European Research Institute for the Biology of Ageing (ERIBA/University Medical Center Groningen).
After awardance of a Rosalind Franklin fellowship (tenure track position) and a KWF Cancer Research career award, Sophia started her own research group at the department of Pediatric Oncology and Hematology/Pediatrics, UMCG (2014). In 2019, Sophia's research group moved to ERIBA, UMCG. Her research aims at understaning how normal neurodevelopmental processes influence pediatric brain cancer initiation and progression.
Netwerk
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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The developmental stage of the medulloblastoma cell-of-origin restricts Hedgehog pathway usage and drug sensitivity
Smit, M. J., Martini, T. E. I., Armandari, I., Bočkaj, I., Zomerman, W. W., de Camargo Magalhães, E. S., Siragna, Z., Meeuwsen, T. G. J., Scherpen, F. J. G., Schoots, M. H., Ritsema, M., den Dunnen, W. F. A., Hoving, E. W., Paridaen, J. T. M. L., de Haan, G., Guryev, V. & Bruggeman, S. W. M., 10-mei-2022, (E-pub ahead of print) In: Journal of Cell Science.Onderzoeksoutput › Academic › peer review
Open AccessBestand1 Downloads (Pure) -
CREB signaling activity correlates with differentiation and survival in medulloblastoma
Armandari, I., Zomerman, W. W., Plasschaert, S. L. A., Smit, M. J., Martini, T. E., Magalhaes, E. S. D. C., Hogeling, S. M., Rozema-Huizinga, G. C., Lourens, H. J., Meeuwsen-de Boer, T. G. J., Scherpen, F. J. G., de Bont, E. S. J. M. & Bruggeman, S. W. M., 9-aug-2021, In: Scientific Reports. 11, 1, 12 blz., 16077.Onderzoeksoutput › Academic › peer review
Open AccessBestand11 Downloads (Pure) -
Heat Shock Factor 1 (HSF1-pSer326) Predicts Response to Bortezomib-Containing Chemotherapy in Pediatric AML: A COG Study
Hoff, F. W., van Dijk, A. D., Qiu, Y. H., Ruvolo, P. P., Gerbing, R. B., Leonti, A. R., Jenkins, G. N., Gamis, A. S., Aplenc, R., Kolb, E. A., Alonzo, T., Meshinchi, S., De Bont, E., Bruggeman, S. W., Kornblau, S. M. & Horton, T. M., 25-feb-2021, In: Blood. 137, 8, blz. 1050-1060 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand2 Citaten (Scopus)32 Downloads (Pure) -
The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma
Bočkaj, I., Martini, T. E. I., de Camargo Magalhães, E. S., Bakker, P. L., Meeuwsen-de Boer, T. G. J., Armandari, I., Meuleman, S. L., Mondria, M. T., Stok, C., Kok, Y. P., Bakker, B., Wardenaar, R., Seiler, J., Broekhuis, M. J. C., van den Bos, H., Spierings, D. C. J., Ringnalda, F. C. A., Clevers, H., Schüller, U., van Vugt, M. A. T. M. & 2 anderen, , nov-2021, In: PLoS genetics. 17, 11, 28 blz., 1009868.Onderzoeksoutput › Academic › peer review
Open AccessBestand12 Downloads (Pure) -
Loss of H3K27 Methylation Identifies Poor Outcome in Adult-Onset Acute Myeloid Leukemia
van Dijk, A. D., Hoff, F. W., Qiu, Y., de Bont, E. S., Bruggeman, S. W. M., Horton, T. M. & Kornblau, S. M., 5-nov-2020, In: Blood. 136, 3 blz.Onderzoeksoutput › Academic
Activiteiten
- 1 Visiting an external institution
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Princess Maxima Ctr Paediat Oncol
Sophia Bruggeman (Visiting researcher)
19-dec-2017Activiteit: Visiting an external institution › Academic
Prijzen
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Differential drug sensitivity in pediatric brain cancer precursor cells: towards tailored treatments for infant and childhood medulloblastoma.
Bruggeman, Sophia (Recipient), 19-jul-2018
Prijs: Fellowship awarded competitively › Academic