Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
- 1 - 50 van 59 resultaten
Zoekresultaten
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2022
Crystal Structure of Levansucrase from the Gram-Negative Bacterium Brenneria Provides Insights into Its Product Size Specificity
Xu, W., Ni, D., Hou, X., Pijning, T., Guskov, A., Rao, Y. & Mu, W., 7-apr-2022, (E-pub ahead of print) In: Journal of Agricultural and Food Chemistry.Onderzoeksoutput › Academic › peer review
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Mutations in Amino Acid Residues of Limosilactobacillus reuteri 121 GtfB 4,6-α-Glucanotransferase that Affect Reaction and Product Specificity
Jiang, Y., Li, X., Pijning, T., Bai, Y. & Dijkhuizen, L., 16-feb-2022, In: Journal of Agricultural and Food Chemistry. 70, 6, blz. 1952-1961 10 blz., 1c07618.Onderzoeksoutput › Academic › peer review
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2021
Crystal structure of an inulosucrase from Halalkalicoccus jeotgali B3T-a halophilic archaeal strain
Ghauri, K., Pijning, T., Munawar, N., Ali, H., Ghauri, M. A., Anwar, M. A. & Wallis, R., okt-2021, In: The FEBS Journal. 288, 19, blz. 5723-5736 14 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand39 Downloads (Pure) -
Enzymatic glucosylation of polyphenols using glucansucrases and branching sucrases of glycoside hydrolase family 70
Li, X., Meng, X., de Leeuw, T. C., Te Poele, E. M., Pijning, T., Dijkhuizen, L. & Liu, W., 15-dec-2021, (E-pub ahead of print) In: Critical Reviews in Food Science and Nutrition. blz. 1-21 21 blz., 2016598.Onderzoeksoutput › Academic › peer review
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Insights into Broad-Specificity Starch Modification from the Crystal Structure of Limosilactobacillus Reuteri NCC 2613 4,6-α-Glucanotransferase GtfB
Pijning, T., Gangoiti, J., Te Poele, E. M., Börner, T. & Dijkhuizen, L., nov-2021, In: Journal of Agricultural and Food Chemistry. 69, 44, blz. 13235-13245 11 blz., 05657.Onderzoeksoutput › Academic › peer review
Open AccessBestand9 Downloads (Pure) -
Using Mutability Landscapes To Guide Enzyme Thermostabilization
Guo, C., Ni, Y., Biewenga, L., Pijning, T., Thunnissen, A-M. W. H. & Poelarends, G. J., 5-jan-2021, In: ChemBioChem. 22, 1, blz. 170-175 7 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand64 Downloads (Pure) -
2019
Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions
Biewenga, L., Thangavelu, S., Kunzendorf, A., Van Der Meer, J., Pijning, T., Tepper, P., Van Merkerk, R., Charnock, S. J., Thunnissen, A. W. H. & Poelarends, G. J., 1-feb-2019, In: ACS Catalysis. 9, blz. 1503-1513 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand20 Citaten (Scopus)120 Downloads (Pure) -
Identification of Thermotoga maritima MSB8 GH57 α-amylase AmyC as a glycogen-branching enzyme with high hydrolytic activity
Zhang, X., Leemhuis, R., Janecek, S., Martinovicova, M., Pijning, T. & van der Maarel, M., aug-2019, In: Applied Microbiology and Biotechnology. 103, 15, blz. 6141–6151 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand2 Citaten (Scopus)119 Downloads (Pure) -
2018
Biochemical and genetic characterization of fungal proline hydroxylase in echinocandin biosynthesis
Zhang, F., Liu, H., Zhang, T., Pijning, T., Yu, L., Zhang, W., Liu, W. & Meng, X., sep-2018, In: Applied Microbiology and Biotechnology. 102, 18, blz. 7877-7890 14 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand7 Citaten (Scopus)21 Downloads (Pure) -
Biochemical characterization of a GH70 protein from Lactobacillus kunkeei DSM 12361 with two catalytic domains involving branching sucrase activity
Meng, X., Gangoiti, J., Wang, X., Grijpstra, P., van Leeuwen, S. S., Pijning, T. & Dijkhuizen, L., sep-2018, In: Applied Microbiology and Biotechnology. 102, 18, blz. 7935-7950 16 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand10 Citaten (Scopus)24 Downloads (Pure) -
Biochemical characterization of two GH70 family 4,6-α-glucanotransferases with distinct product specificity from Lactobacillus aviarius subsp. aviarius DSM 20655
Meng, X., Gangoiti, J., de Kok, N., van Leeuwen, S. S., Pijning, T. & Dijkhuizen, L., 1-jul-2018, In: Food Chemistry. 253, blz. 236-246 11 blz., j.foodchem.2018.01.154.Onderzoeksoutput › Academic › peer review
Open AccessBestand8 Citaten (Scopus)303 Downloads (Pure) -
Mutational Analysis of the Role of the Glucansucrase Gtf180-Delta N Active Site Residues in Product and Linkage Specificity with Lactose as Acceptor Substrate
Pham, H., Pijning, T., Dijkhuizen, L. & van Leeuwen, S. S., 28-nov-2018, In: Journal of Agricultural and Food Chemistry. 66, 47, blz. 12544-12554 11 blz., acs.jafc.8b04486.Onderzoeksoutput › Academic › peer review
Open AccessBestand2 Citaten (Scopus)191 Downloads (Pure) -
2017
4,3-α-Glucanotransferase, a novel reaction specificity in glycoside hydrolase family 70 and clan GH-H
Gangoiti Muñecas, J., van Leeuwen, S. S., Gerwig, G. J., Duboux, S., Vafiadi, C., Pijning, T. & Dijkhuizen, L., 6-jan-2017, In: Scientific Reports. 7, blz. 1-15 15 blz., 39761.Onderzoeksoutput › Academic › peer review
Open AccessBestand16 Citaten (Scopus)291 Downloads (Pure) -
A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy
Franken, L., Oostergetel, G., Pijning, T., Puri, P., Arkhipova, V. I., Boekema, E., Poolman, B. & Guskov, A., 28-sep-2017, In: Nature Communications. 8, 11 blz., 722.Onderzoeksoutput › Academic › peer review
Open AccessBestand30 Citaten (Scopus)325 Downloads (Pure) -
A new group of glycoside hydrolase family 13 α-amylases with an aberrant catalytic triad
Sarian, F. D., Janeček, Š., Pijning, T., Ihsanawati, Nurachman, Z., Radjasa, O. K., Dijkhuizen, L., Natalia, D. & van der Maarel, M. J. E. C., 2017, In: Scientific Reports. 7, 10 blz., 44230.Onderzoeksoutput › Academic › peer review
Open AccessBestand15 Citaten (Scopus)278 Downloads (Pure) -
Biochemical characterization of the functional roles of residues in the active site of the β-galactosidase from Bacillus circulans ATCC 31382
Yin, H., Pijning, T., Meng, X., Dijkhuizen, L. & van Leeuwen, S. S., 2017, In: Biochemistry. 56, 24, blz. 3109-3118 9 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand6 Citaten (Scopus)308 Downloads (Pure) -
Characterization of the glucansucrase GTF180 W1065 mutant enzymes producing polysaccharides and oligosaccharides with altered linkage composition
Meng, X., Pijning, T., Tietema, M., Dobruchowska, J. M., Yin, H., Gerwig, G. J., Kralj, S. & Dijkhuizen, L., 15-feb-2017, In: Food Chemistry. 217, blz. 81-90 10 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand22 Citaten (Scopus)13 Downloads (Pure) -
Crystal Structure of 4,6-α-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from α-Amylases in Oral Bacteria
Bai, Y., Gangoiti, J., Dijkstra, B. W., Dijkhuizen, L. & Pijning, T., 7-feb-2017, In: Structure. 25, 2, blz. 231-242 12 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand25 Citaten (Scopus)351 Downloads (Pure) -
Engineering of the Bacillus circulans β-galactosidase product specificity
Yin, H., Pijning, T., Meng, X., Dijkhuizen, L. & van Leeuwen, S. S., 16-jan-2017, In: Biochemistry. 56, 5, blz. 704-711 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand19 Citaten (Scopus)188 Downloads (Pure) -
Mining novel starch-converting Glycoside Hydrolase 70 enzymes from the Nestlé Culture Collection genome database: The Lactobacillus reuteri NCC 2613 GtfB
Gangoiti, J., van Leeuwen, S. S., Meng, X., Duboux, S., Vafiadi, C., Pijning, T. & Dijkhuizen, L., 30-aug-2017, In: Scientific Reports. 7, 1, 16 blz., 9947.Onderzoeksoutput › Academic › peer review
Open AccessBestand10 Citaten (Scopus)243 Downloads (Pure) -
2016
Lactobacillus reuteri strains convert starch and maltodextrins into homo-exopolysaccharides using an extracellular and cell-associated 4,6-α-glucanotransferase
Bai, Y., Böger, M., van der Kaaij, R. M., Woortman, A. J. J., Pijning, T., van Leeuwen, S. S., Lammerts van Bueren, A. & Dijkhuizen, L., 2016, In: Journal of Agricultural and Food Chemistry. 64, 14, blz. 2941-2952 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand17 Citaten (Scopus)5 Downloads (Pure) -
Structural determinants of alternating (α1 → 4) and (α1 → 6) linkage specificity in reuteransucrase of Lactobacillus reuteri
Meng, X., Pijning, T., Dobruchowska, J. M., Yin, H., Gerwig, G. J. & Dijkhuizen, L., 2016, In: Scientific Reports. 6, 14 blz., 35261.Onderzoeksoutput › Academic › peer review
Open AccessBestand14 Citaten (Scopus)243 Downloads (Pure) -
Structure-function relationships of family GH70 glucansucrase and 4,6-α-glucanotransferase enzymes, and their evolutionary relationships with family GH13 enzymes
Meng, X., Gangoiti, J., Bai, Y., Pijning, T., Van Leeuwen, S. S. & Dijkhuizen, L., jul-2016, In: Cellular and molecular life sciences. 73, 14, blz. 2681-2706 26 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand36 Citaten (Scopus)288 Downloads (Pure) -
Synthesis of New Hyper-Branched α-Glucans from Sucrose by Lactobacillus reuteri 180 Glucansucrase Mutants
Meng, X., Dobruchowska, J. M., Pijning, T., Gerwig, G. J. & Dijkhuizen, L., 20-jan-2016, In: Journal of Agricultural and Food Chemistry. 64, 2, blz. 433-442 10 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand19 Citaten (Scopus)1 Downloads (Pure) -
2015
Biochemical characterization of Lactobacillus reuteri Glycoside Hydrolase family 70 GTFB type of 4,6-α-Glucanotransferase enzymes that synthesize soluble dietary starch fibers
Bai, Y., van der Kaaij, R. M., Leemhuis, H., Pijning, T., van Leeuwen, S. S., Jin, Z. & Dijkhuizen, L., 7-aug-2015, In: Applied and environmental microbiology. 81, 20, blz. 7223-7232 10 blz.Onderzoeksoutput › Academic › peer review
26 Citaten (Scopus) -
Characterization of the functional roles of amino acid residues in acceptor binding subsite +1 in the active site of the glucansucrase GTF180 enzyme of Lactobacillus reuteri 180
Meng, X., Pijning, T., Dobruchowska, J. M., Gerwig, G. J. & Dijkhuizen, L., 11-dec-2015, In: The Journal of Biological Chemistry. 290, 50, blz. 30131-30141 11 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand20 Citaten (Scopus)193 Downloads (Pure) -
The Exiguobacterium sibiricum 255-15 GtfC enzyme representing a novel glycoside hydrolase 70 subfamily of 4,6-α-glucanotransferase enzymes
Gangoiti, J., Pijning, T. & Dijkhuizen, L., 20-nov-2015, In: Applied and environmental microbiology. 82, 2, blz. 756-766 11 blz., AEM.03420-15.Onderzoeksoutput › Academic › peer review
20 Citaten (Scopus) -
Truncation of domain V of the multidomain glucansucrase GTF180 of Lactobacillus reuteri 180 heavily impairs its polysaccharide-synthesizing ability
Meng, X., Dobruchowska, J. M., Pijning, T., Gerwig, G. J., Kamerling, J. P. & Dijkhuizen, L., jul-2015, In: Applied Microbiology and Biotechnology. 99, 14, blz. 5885-5894 10 blz.Onderzoeksoutput › Academic › peer review
20 Citaten (Scopus) -
2014
Flexibility of truncated and full-length glucansucrase GTF180 enzymes from Lactobacillus reuteri 180
Pijning, T., Vujicic - Zagar, A., Kralj, S., Dijkhuizen, L. & Dijkstra, B. W., mei-2014, In: Febs Journal. 281, 9, blz. 2159-2171 13 blz.Onderzoeksoutput › Academic › peer review
15 Citaten (Scopus) -
Improved activity and pH stability of E-coli ATCC 11105 penicillin acylase by error-prone PCR
Balci, H., Ozturk, M. T., Pijning, T., Ozturk, S. I. & Gumusel, F., mei-2014, In: Applied Microbiology and Biotechnology. 98, 10, blz. 4467-4477 11 blz.Onderzoeksoutput › Academic › peer review
13 Citaten (Scopus) -
Residue Leu(940) Has a Crucial Role in the Linkage and Reaction Specificity of the Glucansucrase GTF180 of the Probiotic Bacterium Lactobacillus reuteri 180
Meng, X., Dobruchowska, J. M., Pijning, T., Lopez-Bautista, C., Kamerling, J. P. & Dijkhuizen, L., 21-nov-2014, In: The Journal of Biological Chemistry. 289, 47, blz. 32773-32782 10 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand23 Citaten (Scopus)159 Downloads (Pure) -
2013
4,6-alpha-Glucanotransferase activity occurs more widespread in Lactobacillus strains and constitutes a separate GH70 subfamily
Leemhuis, H., Dijkman, W. P., Dobruchowska, J. M., Pijning, T., Grijpstra, P., Kralj, S., Kamerling, J. P., Dijkhuizen, L. & Gerwig, G. J., jan-2013, In: Applied Microbiology and Biotechnology. 97, 1, blz. 181-193 13 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand35 Citaten (Scopus)635 Downloads (Pure) -
Glucansucrases: Three-dimensional structures, reactions, mechanism, alpha-glucan analysis and their implications in biotechnology and food applications
Leemhuis, H., Pijning, T., Dobruchowska, J. M., van Leeuwen, S. S., Kralj, S., Dijkstra, B. W. & Dijkhuizen, L., 20-jan-2013, In: Journal of Biotechnology. 163, 2, blz. 250-272 23 blz.Onderzoeksoutput › Academic › peer review
190 Citaten (Scopus)424 Downloads (Pure) -
Improved activity and thermostability of Bacillus pumilus lipase by directed evolution
Akbulut, N., Ozturk, M. T., Pijning, T., Ozturk, S. I. & Gumusel, F., 10-mrt-2013, In: Journal of Biotechnology. 164, 1, blz. 123-129 7 blz.Onderzoeksoutput › Academic › peer review
53 Citaten (Scopus) -
2012
Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: Factors contributing to increased activity retention
Augustyniak, W., Brzezinska, A. A., Pijning, T., Wienk, H., Boelens, R., Dijkstra, B. W. & Reetz, M. T., apr-2012, In: Protein Science. 21, 4, blz. 487-497 11 blz.Onderzoeksoutput › Academic › peer review
41 Citaten (Scopus)161 Downloads (Pure) -
Functional and Structural Characterization of alpha-(1 -> 2) Branching Sucrase Derived from DSR-E Glucansucrase
Brison, Y., Pijning, T., Malbert, Y., Fabre, E., Mourey, L., Morel, S., Potocki-Veronese, G., Monsan, P., Tranier, S., Remaud-Simeon, M. & Dijkstra, B. W., 9-mrt-2012, In: The Journal of Biological Chemistry. 287, 11, blz. 7915-7924 10 blz.Onderzoeksoutput › Academic › peer review
63 Citaten (Scopus)116 Downloads (Pure) -
Glycosidic bond specificity of glucansucrases: on the role of acceptor substrate binding residues
Leemhuis, H., Pijning, T., Dobruchowska, J. M., Dijkstra, B. W. & Dijkhuizen, L., mei-2012, In: Biocatalysis and Biotransformation. 30, 3, blz. 366-376 11 blz.Onderzoeksoutput › Academic › peer review
41 Citaten (Scopus)198 Downloads (Pure) -
Structure of the alpha-1,6/alpha-1,4-specific glucansucrase GTFA from Lactobacillus reuteri 121
Pijning, T., Vujicic-Zagar, A., Kralj, S., Dijkhuizen, L. & Dijkstra, B. W., dec-2012, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 68, 12, blz. 1448-1454 7 blz.Onderzoeksoutput › Academic › peer review
48 Citaten (Scopus)104 Downloads (Pure) -
The role of conserved inulosucrase residues in the reaction and product specificity of Lactobacillus reuteri inulosucrase
Anwar, M. A., Leemhuis, H., Pijning, T., Kralj, S., Dijkstra, B. W. & Dijkhuizen, L., okt-2012, In: Febs Journal. 279, 19, blz. 3612-3621 10 blz.Onderzoeksoutput › Academic › peer review
18 Citaten (Scopus)71 Downloads (Pure) -
2011
Crystal Structure of Inulosucrase from Lactobacillus: Insights into the Substrate Specificity and Product Specificity of GH68 Fructansucrases
Pijning, T., Anwar, M. A., Boger, M., Dobruchowska, J. M., Leemhuis, H., Kralj, S., Dijkhuizen, L. & Dijkstra, B. W., 9-sep-2011, In: Journal of Molecular Biology. 412, 1, blz. 80-93 14 blz.Onderzoeksoutput › Academic › peer review
46 Citaten (Scopus) -
Thermus thermophilus Glycoside Hydrolase Family 57 Branching Enzyme: Crystal Structure, Mechanism of Action, and Products Formed
Palomo, M., Pijning, T., Booiman, T., Dobruchowska, J. M., Vlist, J. V. D., Kralj, S., Planas, A., Loos, K., Kamerling, J. P., Dijkstra, B. W., Maarel, M. J. E. C. V. D., Dijkhuizen, L. & Leemhuis, H., 4-feb-2011, In: The Journal of Biological Chemistry. 286, 5, blz. 3520-3530 11 blz.Onderzoeksoutput › Academic › peer review
67 Citaten (Scopus) -
2010
Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes
Vujičić-Žagar, A., Pijning, T., Kralj, S., López, C. A., Eeuwema, W., Dijkhuizen, L. & Dijkstra, B. W., 14-dec-2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 50, blz. 21406-21411 6 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand109 Citaten (Scopus)731 Downloads (Pure) -
Crystal Structure of the Leucine Aminopeptidase from Pseudomonas putida Reveals the Molecular Basis for its Enantioselectivity and Broad Substrate Specificity
Kale, A., Pijning, T., Sonke, T., Dijkstra, B. W. & Thunnissen, A-M. W. H., 21-mei-2010, In: Journal of Molecular Biology. 398, 5, blz. 703-714 12 blz.Onderzoeksoutput › Academic › peer review
23 Citaten (Scopus)295 Downloads (Pure) -
2009
The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer
Pijning, T., van Pouderoyen, G., Kluskens, L., van der Oost, J. & Dijkstra, B. W., 19-nov-2009, In: FEBS Letters. 583, 22, blz. 3665-3670 6 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand17 Citaten (Scopus)318 Downloads (Pure) -
2008
A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A
Boersma, Y. L., Droge, M. J., van der Sloot, A. M., Pijning, T., Cool, R. H., Dijkstra, B. W., Quax, W. J. & Dröge, M. J., 5-mei-2008, In: ChemBioChem. 9, 7, blz. 1110-1115 6 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand45 Citaten (Scopus)322 Downloads (Pure) -
Biochemical and crystallographic characterization of a glucansucrase from Lactobacillus reuteri 180
Pijning, T., Vujicic-Zagar, A., Kralj, S., Eeuwema, W., Dijkhuizen, L. & Dijkstra, B. W., 2008, In: Biocatalysis and Biotransformation. 26, 1-2, blz. 12-17 6 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand30 Citaten (Scopus)301 Downloads (Pure) -
Loop grafting of Bacillus subtilis lipase A: Inversion of enantioselectivity
Boersma, Y. L., Pijning, T., Bosma, M., van der Sloot, A. M., da Silva Godinho, L., Dröge, M., Winter, R. T., van Pouderoyen, G., Dijkstra, B. W. & Quax, W., 25-aug-2008, In: Chemistry & Biology. 15, 8, blz. 782-789 8 blz.Onderzoeksoutput › Academic › peer review
29 Citaten (Scopus) -
2005
A crystallographic study of Cys69Ala flavodoxin II from Azotobacter vinelandii: Structural determinants of redox potential: Structural determinants of redox potential
Alagaratnam, S., van Pouderoyen, G., Pijning, T., Dijkstra, B. W., Cavazzini, D., Rossi, G. L., Van Dongen, W. M. A. M., Van Mierlo, C. P. M., Canters, G. W. & Van Berkel, WJH., 2005, In: Protein Science. 14, 9, blz. 2284 - 2295 12 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand45 Citaten (Scopus)255 Downloads (Pure) -
2003
Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39
Fusetti, F., Pijning, T., Kalk, KH., Bos, E., Dijkstra, BW. & Dijkstra, B. W., 26-sep-2003, In: The Journal of Biological Chemistry. 278, 39, blz. 37753-37760 8 blz.Onderzoeksoutput › Academic › peer review
Open AccessBestand149 Citaten (Scopus)301 Downloads (Pure) -
2002
Crystal structure of the copper-containing quercetin 2,3-dioxygenase from Aspergillus japonicus
Fusetti, F., Schröter, K. H., Steiner, R. A., Noort, P. I. V., Pijning, T., Rozeboom, H. J., Kalk, K. H., Egmond, M. R. & Dijkstra, B. W., feb-2002, In: Structure. 10, 2, blz. 259-268 10 blz.Onderzoeksoutput › Academic
Open AccessBestand183 Citaten (Scopus)391 Downloads (Pure)