Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

BBJ, BioMe, BioVU, Canadian Partnership for Tomorrow's Health/OHS, China Kadoorie Biobank Collaborative Group, Colorado Center for Personalized Medicine, deCODE Genetics, ESTBB, FinnGen, Generation Scotland, Genes & Health, LifeLines, Mass General Brigham Biobank, Michigan Genomics Initiative, QIMR Berghofer Biobank, Taiwan Biobank, The HUNT Study, UCLA ATLAS Community Health Initiative, UKBB, Wang, Y., & 22 anderenNamba, S., Lopera, E., Tsuo, K., Läll, K., Kanai, M., Zhou, W., Wu, K. H. H., Favé, M. J., Bhatta, L., Awadalla, P., Brumpton, B., Deelen, P., Hveem, K., Lo Faro, V., Mägi, R., Murakami, Y., Sanna, S., Smoller, J. W., Uzunovic, J., Wolford, B. N., Martin, A. R. & Hirbo, J. B., 11-jan.-2023, In: Cell Genomics. 3, 1, 18 blz., 100241.

Onderzoeksoutput: Article › Academic › peer review

Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease

deCODE Genetics, Estonian Biobank, FinnGen, Generation Scotland, Genes & Health Research Team, LifeLines, Mass General Brigham Biobank, Michigan Genomics Initiative, National Biobank of Korea, Penn Medicine BioBank, Qatar Biobank, The QSkin Sun and Health Study, Taiwan Biobank, The HUNT Study, UCLA ATLAS Community Health Initiative, Uganda Genome Resource, UK Biobank, Biobank of the Americas, BioBank Japan Project, BioMe, & 54 anderenBioVU, CanPath - Ontario Health Study, China Kadoorie Biobank Collaborative Group, Colorado Center for Personalized Medicine, Zhou, W., Kanai, M., Wu, K. H. H., Rasheed, H., Tsuo, K., Hirbo, J. B., Wang, Y., Bhattacharya, A., Zhao, H., Namba, S., Surakka, I., Wolford, B. N., Lo Faro, V., Lopera-Maya, E. A., Läll, K., Favé, M. J., Partanen, J. J., Chapman, S. B., Karjalainen, J., Kurki, M., Maasha, M., Brumpton, B. M., Chavan, S., Chen, T. T., Daya, M., Ding, Y., Feng, Y. C. A., Guare, L. A., Gignoux, C. R., Graham, S. E., Hornsby, W. E., Ingold, N., Ismail, S. I., Johnson, R., Laisk, T., Lin, K., Lv, J., Millwood, I. Y., Moreno-Grau, S., Nam, K., Palta, P., Pandit, A., de Bock, G. H., Jansonius, N. M., Boezen, M., Franke, L., Snieder, H., Vonk, J. M., Wijmenga, C. & Sanna, S., 12-okt.-2022, In: Cell Genomics. 2, 10, 15 blz., 100192.

Onderzoeksoutput: Article › Academic › peer review

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

Global Biobank Meta-analysis Initiative, Kanai, M., Elzur, R., Zhou, W., Daly, M. J. & Finucane, H. K., 14-dec.-2022, In: Cell Genomics. 2, 12, 22 blz., 100210.

Onderzoeksoutput: Article › Academic › peer review

A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus

Hardcastle, A. J., Liskova, P., Bykhovskaya, Y., McComish, B. J., Davidson, A. E., Inglehearn, C. F., Li, X., Choquet, H., Habeeb, M., Lucas, S. E. M., Sahebjada, S., Pontikos, N., Lopez, K. E. R., Khawaja, A. P., Ali, M., Dudakova, L., Skalicka, P., Van Dooren, B. T. H., Geerards, A. J. M., Haudum, C. W., & 30 anderenLo Faro, V., Tenen, A., Simcoe, M. J., Patasova, K., Yarrand, D., Yin, J., Siddiqui, S., Rice, A., Farraj, L. A., Chen, Y-D. I., Rahi, J. S., Krauss, R. M., Theusch, E., Charlesworth, J. C., Szczotka-Flynn, L., Toomes, C., Meester-Smoor, M. A., Richardson, A. J., Mitchell, P. A., Taylor, K. D., Melles, R. B., Aldave, A. J., Mills, R. A., Cao, K., Chan, E., Daniell, M. D., Wang, J. J., Rotter, J. I., Hewitt, A. W. & MacGregor, S., 1-mrt.-2021, In: Communications biology. 4, 1, 13 blz., 266.

Onderzoeksoutput: Article › Academic › peer review