Early developmental processes underlying sensory deficits in neurodevelopmental disorders



Autism spectrum disorder (ASD) represents a group of complex neurodevelopmental disorders of strikingly high incidence. The traditional clinical features of ASD are weaknesses in social communicative abilities and restricted interests and repetitive behaviors. As now formally recognized in the DSM-5, children with ASD frequently suffer from disturbances in sensory reactivity. In fact, sensory abnormalities are one of the most prevalent symptoms of ASD, reported in up to 87% of individuals. In this project, We aim to unravel the causal relationship between aberrations in early activity patterns, miss-wiring of brain circuits, and sensory malfunction in later life.
Effectieve start/einddatum01/11/201701/01/2023