TY - JOUR
T1 - [15O]H2O PET
T2 - Potential or Essential for Molecular Imaging?
AU - Slart, Riemer H J A
AU - Martinez-Lucio, T Samara
AU - Boersma, Hendrikus H
AU - Borra, Ronald H
AU - Cornelissen, Bart
AU - Dierckx, Rudi A J O
AU - Dobrolinska, Magdalena
AU - Doorduin, Janine
AU - Erba, Paola A
AU - Glaudemans, Andor W J M
AU - Giacobbo, Bruno Lima
AU - Luurtsema, Gert
AU - Noordzij, Walter
AU - van Sluis, Joyce
AU - Tsoumpas, Charalampos
AU - Lammertsma, Adriaan A
N1 - Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.
PY - 2024/9
Y1 - 2024/9
N2 - Imaging water pathways in the human body provides an excellent way of measuring accurately the blood flow directed to different organs. This makes it a powerful diagnostic tool for a wide range of diseases that are related to perfusion and oxygenation. Although water PET has a long history, its true potential has not made it into regular clinical practice. The article highlights the potential of water PET in molecular imaging and suggests its prospective role in becoming an essential tool for the 21st century precision medicine in different domains ranging from preclinical to clinical research and practice. The recent technical advances in high-sensitivity PET imaging can play a key accelerating role in empowering this technique, though there are still several challenges to overcome.
AB - Imaging water pathways in the human body provides an excellent way of measuring accurately the blood flow directed to different organs. This makes it a powerful diagnostic tool for a wide range of diseases that are related to perfusion and oxygenation. Although water PET has a long history, its true potential has not made it into regular clinical practice. The article highlights the potential of water PET in molecular imaging and suggests its prospective role in becoming an essential tool for the 21st century precision medicine in different domains ranging from preclinical to clinical research and practice. The recent technical advances in high-sensitivity PET imaging can play a key accelerating role in empowering this technique, though there are still several challenges to overcome.
U2 - 10.1053/j.semnuclmed.2023.08.002
DO - 10.1053/j.semnuclmed.2023.08.002
M3 - Review article
C2 - 37640631
SN - 0001-2998
VL - 54
SP - 761
EP - 773
JO - Seminars in Nuclear Medicine
JF - Seminars in Nuclear Medicine
IS - 5
ER -