A concise review of microfluidic particle manipulation methods

Shuaizhong Zhang, Ye Wang, Patrick Onck, Jaap den Toonder*

*Bijbehorende auteur voor dit werk

Onderzoeksoutputpeer review

9 Citaten (Scopus)
87 Downloads (Pure)


Particle manipulation is often required in many applications such as bioanalysis, disease diagnostics, drug delivery and self-cleaning surfaces. The fast progress in micro- and nano-engineering has contributed to the rapid development of a variety of technologies to manipulate particles including more established methods based on microfluidics, as well as recently proposed innovative methods that still are in the initial phases of development, based on self-driven microbots and artificial cilia. Here, we review these techniques with respect to their operation principles and main applications. We summarize the shortcomings and give perspectives on the future development of particle manipulation techniques. Rather than offering an in-depth, detailed, and complete account of all the methods, this review aims to provide a broad but concise overview that helps to understand the overall progress and current status of the diverse particle manipulation methods. The two novel developments, self-driven microbots and artificial cilia-based manipulation, are highlighted in more detail.

Originele taal-2English
Aantal pagina's20
TijdschriftMicrofluidics and Nanofluidics
Nummer van het tijdschrift4
StatusPublished - 19-mrt-2020

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