A multicomponent tetrazolo indole synthesis

Xiaofang Lei, Panagiota Lampiri, Pravin Patil, Giasemi Angeli, Constantinos G Neochoritis*, Alexander Dömling*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

5 Citaten (Scopus)
29 Downloads (Pure)

Samenvatting

The ubiquitous presence of the indole fragment in natural products and drugs asks for ever novel syntheses. We report an unprecedented mild, two-step synthesis of 2-tetrazolo substituted indoles based on the Ugi-tetrazole reaction combined with an acidic ring closure. A gram-scale synthesis, a bioactive compound and further transformations were performed.

Originele taal-2English
Pagina's (van-tot)6652-6655
Aantal pagina's4
TijdschriftChemical communications (Cambridge, England)
Volume57
Nummer van het tijdschrift54
DOI's
StatusPublished - 6-jul.-2021

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