Samenvatting
The ubiquitous presence of the indole fragment in natural products and drugs asks for ever novel syntheses. We report an unprecedented mild, two-step synthesis of 2-tetrazolo substituted indoles based on the Ugi-tetrazole reaction combined with an acidic ring closure. A gram-scale synthesis, a bioactive compound and further transformations were performed.
Originele taal-2 | English |
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Pagina's (van-tot) | 6652-6655 |
Aantal pagina's | 4 |
Tijdschrift | Chemical communications (Cambridge, England) |
Volume | 57 |
Nummer van het tijdschrift | 54 |
DOI's | |
Status | Published - 6-jul.-2021 |
Datasets
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CCDC 2077271: Experimental Crystal Structure Determination
Lei, X. (Contributor), Lampiri, P. (Contributor), Patil, P. (Contributor), Angeli, G. (Contributor), Neochoritis, C. G. (Contributor) & Dömling, A. (Contributor), The Cambridge Structural Database, 13-apr.-2021
DOI: 10.5517/ccdc.csd.cc27qkr9
Dataset