A study of medication reviews to identify drug-related problems of polypharmacy patients in the Dutch nursing home setting

F. Finkers, J. G. Maring*, F. Boersma, K. Taxis

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

71 Citaten (Scopus)


Background: Little is known about the extent of drug-related problems of polypharmacy patients in Dutch nursing homes.

Objectives: We investigated the feasibility of teams of hospital pharmacists and nursing home physicians carrying out medication reviews. We aimed to identify the number and nature of drug-related problems of nursing home patients receiving more than nine drugs (polypharmacy).

Methods: The study was carried out in five Dutch nursing homes (n = 742 beds) between October 2005 and May 2006. Ninety-one polypharmacy patients, (average age 80 years) were included. A medication review was carried out by teams consisting of one hospital pharmacist and the patient's nursing home physician with a follow-up meeting of the same team 6 weeks later.

Results: A total of 323 drug-related problems were identified (mean of 3.5 problems per patient). Sixty-two per cent of problems, in 87% of patients, were classified as 'unclear or not confirmed indication or need for review' of the prescribed drug. By the time of the follow-up, a mean of 1.7 (n = 159) problems per patient had been solved and the number of drugs per patient had decreased significantly from 13.5 to 12.7 (P <0.0001).

Conclusions: The majority of patients had at least one drug prescribed for which the indication was unknown. The intervention was accompanied by a significant decrease in the number of drugs per patient, but half of the drug-related problems remained unsolved.

Originele taal-2English
Pagina's (van-tot)469-476
Aantal pagina's8
TijdschriftJournal of Clinical Pharmacy and Therapeutics
Nummer van het tijdschrift5
StatusPublished - okt-2007

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