Affect and physical health: Studies on the link between affect and physiological processes

Maria Schenk

Affect and physical health: Studies on the link between affect and physiological processes

Vertaalde titel van de bijdrage: Affect en gezondheid: Studies over de relatie tussen affect en fysiologische processen

Maria Schenk

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Samenvatting

Het doel van het onderzoek is het bestuderen van de relatie tussen positief en negatief affect en gezondheid tussen en binnen personen. Om de relatie tussen affect en fysiologische processen goed te begrijpen heeft een zogenaamde tijdsreeksanalyse de voorkeur. Hierbij volg je personen intensief over de tijd, dus je meet vaak en het liefst in de alledaagse omgeving. Helaas is het onhaalbaar om meerdere keren per dag bloed te prikken om de concentratie van biomarkers te kunnen bepalen. Gelukkig kunnen biomarkers ook bepaald worden in onder andere speeksel, nagels, haar en urine, oftewel non-invasief.
We hebben de mogelijkheid biomarkers te meten in non-invasieve monsters verder onderzocht. Verder staat in het eerste deel van de dissertatie het online platform Physiqual beschreven. Dit is ontwikkeld om dagboekdata te combineren met fysiologische data, verzameld met wearables. In deel twee is er gekeken naar de associatie tussen affect, somatische symptomen en biomarkers. Dit is gedaan op groepsniveau en op individueel niveau in een intensieve (dagboek)studie.
We hebben aangetoond dat het mogelijk is om de concentratie van specifieke biomarkers te meten in verschillende non-invasieve monsters, verzameld door deelnemers die hun dagelijkse routine bleven volgen. Tevens suggereren de bevindingen dat het hebben van positief affect een positieve invloed heeft op de gezondheidstoestand. Dit belang van positief effect werd aangetoond op zowel groepsniveau als op individueel niveau. Op individueel niveau waren de bevindingen echter erg gevarieerd, wat laat zien dat individuen van elkaar verschillen en resultaten gevonden op groepsniveau niet zomaar vertaald kunnen worden naar het individu.

Vertaalde titel van de bijdrage	Affect en gezondheid: Studies over de relatie tussen affect en fysiologische processen
Originele taal-2	English
Kwalificatie	Doctor of Philosophy
Toekennende instantie	Rijksuniversiteit Groningen
Begeleider(s)/adviseur	Rosmalen, Judith, Supervisor de Jonge, Peter, Supervisor Slaets, Joris, Supervisor
Datum van toekenning	12-jul.-2017
Plaats van publicatie	[Groningen]
Uitgever	Rijksuniversiteit Groningen
Gedrukte ISBN's	978-90-367-9873-0
Status	Published - 2017

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Title and contentsFinal publisher's version, 183 KB
Chapter 1Final publisher's version, 223 KB
Chapter 2Final publisher's version, 371 KB
Chapter 3Final publisher's version, 368 KB
Chapter 4Final publisher's version, 931 KB
Chapter 5Final publisher's version, 795 KB
Chapter 6Final publisher's version, 348 KB
Chapter 7Final publisher's version, 377 KB
Chapter 8Final publisher's version, 311 KB
Chapter 9Final publisher's version, 314 KB
SummaryFinal publisher's version, 153 KB
Nederlandse samenvattingFinal publisher's version, 193 KB
DankwoordFinal publisher's version, 86,8 KB
SHAREFinal publisher's version, 114 KB
Complete thesisFinal publisher's version, 3,12 MB
PropositionsFinal publisher's version, 42,6 KB

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Permanente koppeling

Lifelines Biobank
Bakker, S. (Creator), Dotinga, A. (Creator), Vonk, J. M. (Creator), Smidt, N. (Creator), Scholtens, S. (Creator), Swertz, M. (Creator), Wijmenga, C. (Creator), Wolffenbutel, B. H. (Creator), Stolk, R. (Creator), van Zon, S. (Creator), Rosmalen, J. (Creator), Postma, D. S. (Creator), de Boer, R. (Creator), Navis, G. (Creator), Slaets, J. (Creator), Ormel, J. (Creator), van Dijk, F. (Creator) & Bolmer, B. (Data Manager), Lifelines, 2006
https://www.lifelines.nl/ en nog één link, https://catalogue.lifelines.nl/ (minder tonen)
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Citeer dit

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title = "Affect and physical health: Studies on the link between affect and physiological processes",

abstract = "The main goal of this thesis was to study the association between affect and health at both the between-subject and the within-subject level. Especially for the latter, time series analyses are a necessity. Time series are formed by multiple observations in one individual, and can be collected in an intensive day-to-day study design. To reduce the burden of the research protocol on participants, we explored the possibilities of non-invasive sampling to measure biomarker levels. In addition, we explored the possibility to combine self-reported diary data with physiological data from existing technologies, like Fitbit or smartwatches. In the second part of the thesis, we examined the associations between both positive affect (PA) and negative affect (NA) and health indicators at both the between-subject and the within-subject level. Overall, it was shown to be feasible to measure physiological biomarkers in samples which can be obtained non-invasively in an intensive day-to-day study. In addition, the findings in this thesis imply that PA has a positive effect on health.PA is inversely associated with somatic symptoms and detrimental biomarkers, both at the between-individual and the within-individual level. However, the associations found within individuals are heterogeneous, meaning that the associations differ between individuals. More research is necessary to better understand the effect of affect, the possible protective role of PA, and pathological effects of psychopathology in the long run.",

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N2 - The main goal of this thesis was to study the association between affect and health at both the between-subject and the within-subject level. Especially for the latter, time series analyses are a necessity. Time series are formed by multiple observations in one individual, and can be collected in an intensive day-to-day study design. To reduce the burden of the research protocol on participants, we explored the possibilities of non-invasive sampling to measure biomarker levels. In addition, we explored the possibility to combine self-reported diary data with physiological data from existing technologies, like Fitbit or smartwatches. In the second part of the thesis, we examined the associations between both positive affect (PA) and negative affect (NA) and health indicators at both the between-subject and the within-subject level. Overall, it was shown to be feasible to measure physiological biomarkers in samples which can be obtained non-invasively in an intensive day-to-day study. In addition, the findings in this thesis imply that PA has a positive effect on health.PA is inversely associated with somatic symptoms and detrimental biomarkers, both at the between-individual and the within-individual level. However, the associations found within individuals are heterogeneous, meaning that the associations differ between individuals. More research is necessary to better understand the effect of affect, the possible protective role of PA, and pathological effects of psychopathology in the long run.

AB - The main goal of this thesis was to study the association between affect and health at both the between-subject and the within-subject level. Especially for the latter, time series analyses are a necessity. Time series are formed by multiple observations in one individual, and can be collected in an intensive day-to-day study design. To reduce the burden of the research protocol on participants, we explored the possibilities of non-invasive sampling to measure biomarker levels. In addition, we explored the possibility to combine self-reported diary data with physiological data from existing technologies, like Fitbit or smartwatches. In the second part of the thesis, we examined the associations between both positive affect (PA) and negative affect (NA) and health indicators at both the between-subject and the within-subject level. Overall, it was shown to be feasible to measure physiological biomarkers in samples which can be obtained non-invasively in an intensive day-to-day study. In addition, the findings in this thesis imply that PA has a positive effect on health.PA is inversely associated with somatic symptoms and detrimental biomarkers, both at the between-individual and the within-individual level. However, the associations found within individuals are heterogeneous, meaning that the associations differ between individuals. More research is necessary to better understand the effect of affect, the possible protective role of PA, and pathological effects of psychopathology in the long run.

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Affect and physical health: Studies on the link between affect and physiological processes

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