Allergy-specific immunotherapy compositions for use in the treatment of house-dust mite allergy

Gerrit Jan Willem Euverink (Uitvinder), Laura Hesse (Uitvinder), Martijn Christiaan Nawijn (Uitvinder), Adrianus Cornelis van der Graaf (Uitvinder)

Onderzoeksoutput

Samenvatting

The present invention relates to a composition comprising purified natural Der p1 and purified natural Der p2 allergens for use in the treatment of house-dust mite allergy in mammals, like humans. The invention further pertains pharmaceutical compositions for allergy-specific immune therapy. Specifically, the invention discloses reduced responsiveness to subsequent house dust mite allergen exposure after treatment with a pharmaceutical composition comprising purified natural Der p1 and purified natural Der p2 characterized by reduction in Th2 cell activity and reduction in CCL20 release.
Originele taal-2English
OctrooinummerWO2016193126
Prioriteitsdatum29/05/2015
StatusPublished - 8-dec-2016

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