TY - JOUR
T1 - Alternative PET tracers in head and neck cancer. A review
AU - Wedman, Jan
AU - Pruim, Jan
AU - Roodenburg, Jan L. N.
AU - Halmos, Gyorgy
AU - Langedijk, Johannes A.
AU - Dierckx, Rudi A. J. O.
AU - van der Laan, Bernard F. A. M.
PY - 2013/9
Y1 - 2013/9
N2 - Positron emission tomography (PET) has become a standard in staging Head and Neck cancer. While F-18-fluoro-2-deoxy-d-glucose (FDG) is the most frequently used radiopharmaceutical, glycolysis is not the only metabolic process that can be visualized. Different PET tracers can also be used to visualize other metabolic processes and in this manner, the disadvantages of FDG PET can be avoided. In this review, we describe a comprehensive overview of alternatives to FDG that can be used in identifying head and neck cancer. The potential advantages and disadvantages of these radiopharmaceuticals are discussed.
AB - Positron emission tomography (PET) has become a standard in staging Head and Neck cancer. While F-18-fluoro-2-deoxy-d-glucose (FDG) is the most frequently used radiopharmaceutical, glycolysis is not the only metabolic process that can be visualized. Different PET tracers can also be used to visualize other metabolic processes and in this manner, the disadvantages of FDG PET can be avoided. In this review, we describe a comprehensive overview of alternatives to FDG that can be used in identifying head and neck cancer. The potential advantages and disadvantages of these radiopharmaceuticals are discussed.
KW - PET
KW - Amino acids
KW - Nucleoside
KW - Hypoxia
KW - Monoclonal antibodies
KW - POSITRON-EMISSION-TOMOGRAPHY
KW - SQUAMOUS-CELL CARCINOMA
KW - PROTEIN-SYNTHESIS RATE
KW - TUMOR HYPOXIA
KW - EARLY RESPONSE
KW - F-18-FDG PET
KW - MONOCLONAL-ANTIBODIES
KW - LARYNGEAL CARCINOMAS
KW - KINETIC-ANALYSIS
KW - C-11 METHIONINE
U2 - 10.1007/s00405-012-2316-9
DO - 10.1007/s00405-012-2316-9
M3 - Review article
C2 - 23269395
SN - 0937-4477
VL - 270
SP - 2595
EP - 2601
JO - European Archives of Oto-Rhino-Laryngology
JF - European Archives of Oto-Rhino-Laryngology
IS - 10
ER -