Background: There is no population based study about prevalence of psychiatric conditions in Kermanshah. A screening study reported the rate of 39.1% for psychiatric disorders. Methods: This is the second phase of a larger study. From those with a positive screening, 15% were randomly selected and interviewed face-to-face at home by trained clinical psychologists with Farsi version of the structured clinical interview for DSM-IV (SCID)I and II. Results: The original sample was 2102 participants, from those 319 individuals were interviewed. Only 15 participants (4.7% of the positively screened sample)had a negative result. Major depressive disorder (8.3%), generalized anxiety disorder (4.7%), obsessive compulsive disorder (4.6%)and obsessive compulsive personality disorder (3.3%)were the most common disorders diagnosed within this sample. Conclusion: This population based study gives prevalence rates for psychiatric disorders in Kermanshah for the first time. Results can be the basis for health care policy makers and further studies.