TY - JOUR
T1 - An Examination of the Food Allergy Quality of Life Questionnaire Performance in a Countrywide American Sample of Children
T2 - Cross-Cultural Differences in Age and Impact in the United States and Europe
AU - DunnGalvin, Audrey
AU - Koman, Elizabeth
AU - Raver, Elizabeth
AU - Frome, Hayley
AU - Adams, Melissa
AU - Keena, Aisleen
AU - Hourihane, Jonathan O'B.
AU - Gallagher, Patricia Leahy
AU - Flokstra-de Blok, Bertine
AU - Dubois, Anthony
AU - Pyrz, Katarzyna
AU - Bindslev-Jensen, Cartsen
AU - Stensgaard, Anette
AU - Boyle, Robert
AU - Vickers, Bea
AU - Smith, Jared
AU - Thisanayagam, Umasunthar
AU - Greenhawt, Matthew
PY - 2017/3
Y1 - 2017/3
N2 - BACKGROUND: It is important to ensure that tools are valid and reliable in the context in which they are used. The development of age and country norms is part of this process.OBJECTIVES: The primary aim of the present study was to examine the performance of the Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF) in a countrywide American sample of children with food allergy. The secondary aim was to compare age differences in impact across 9 European countries.METHODS: In a cross-sectional quantitative design, questionnaires were completed by the parents of 1029 food-allergic children (0-12 years). Participants were recruited via support groups and allergists. Data were analyzed by using multivariate analysis of variance and tests for internal consistency and validity. The average score was calculated for each age group in 15 studies in Ireland, Switzerland, the Netherlands, Spain, Portugal, Germany, Italy, Denmark, Israel, and the United Kingdom.RESULTS: The FAQLQ-PF has high convergent validity (child: r = 0.49, n = 695, P = .01; parent: r = 0.36, n = 696, P = .01) and discriminant validity, parent: t (719) = 4.67, P = .001 (anaphylaxis yes vs no); t (513), P = .009 (single vs multiple allergens). Internal consistency was excellent (r = 0.96). US health-related quality of life was worse than European health-related quality of life, as indicated by higher FAQLQ-PF scores in US samples. Burden increased with age in all populations.CONCLUSIONS: The FAQLQ-PF is appropriate for use in an American population. Findings will form the basis for further work in the development of an online manual with food allergy-normed age scores to allow for precise measurement, interpretation of scores, and comparison across countries and cultures, in clinical and research settings. (C) 2016 American Academy of Allergy, Asthma & Immunology
AB - BACKGROUND: It is important to ensure that tools are valid and reliable in the context in which they are used. The development of age and country norms is part of this process.OBJECTIVES: The primary aim of the present study was to examine the performance of the Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF) in a countrywide American sample of children with food allergy. The secondary aim was to compare age differences in impact across 9 European countries.METHODS: In a cross-sectional quantitative design, questionnaires were completed by the parents of 1029 food-allergic children (0-12 years). Participants were recruited via support groups and allergists. Data were analyzed by using multivariate analysis of variance and tests for internal consistency and validity. The average score was calculated for each age group in 15 studies in Ireland, Switzerland, the Netherlands, Spain, Portugal, Germany, Italy, Denmark, Israel, and the United Kingdom.RESULTS: The FAQLQ-PF has high convergent validity (child: r = 0.49, n = 695, P = .01; parent: r = 0.36, n = 696, P = .01) and discriminant validity, parent: t (719) = 4.67, P = .001 (anaphylaxis yes vs no); t (513), P = .009 (single vs multiple allergens). Internal consistency was excellent (r = 0.96). US health-related quality of life was worse than European health-related quality of life, as indicated by higher FAQLQ-PF scores in US samples. Burden increased with age in all populations.CONCLUSIONS: The FAQLQ-PF is appropriate for use in an American population. Findings will form the basis for further work in the development of an online manual with food allergy-normed age scores to allow for precise measurement, interpretation of scores, and comparison across countries and cultures, in clinical and research settings. (C) 2016 American Academy of Allergy, Asthma & Immunology
KW - Food Allergy
KW - Quality of life Questionnaire
KW - Quality of life
KW - Measurement precision
KW - Normed scores
KW - RANDOMIZED CONTROLLED-TRIAL
KW - YOUNG-ADULTS
KW - ANAPHYLAXIS
KW - ADOLESCENTS
KW - CHALLENGES
KW - VALIDITY
KW - PEOPLE
KW - MILK
KW - FORM
U2 - 10.1016/j.jaip.2016.09.049
DO - 10.1016/j.jaip.2016.09.049
M3 - Article
SN - 2213-2198
VL - 5
SP - 363-368.e2
JO - The Journal of Allergy and Clinical Immunology: In Practice
JF - The Journal of Allergy and Clinical Immunology: In Practice
IS - 2
ER -