An Open-Label Discontinuation Trial of Long-Term, Off-Label Antipsychotic Medication in People With Intellectual Disability: Determinants of Success and Failure

Gerda M. de Kuijper, Pieter J. Hoekstra

Onderzoeksoutput: ArticleAcademicpeer review

16 Citaten (Scopus)
251 Downloads (Pure)


Although physicians are aware of the risks of prescribing long-term off-label antipsychotics in people with intellectual disability, attempts to discontinue often fail. This study aimed to identify potential determinants of successful and failed discontinuation. Long-term off-label antipsychotics were tapered in 14 weeks, with 12.5% of baseline dose every 2 weeks. Participants living in facilities offered by intellectual disability service providers, >= 6 years, with an IQ

Originele taal-2English
Pagina's (van-tot)1418-1426
Aantal pagina's9
TijdschriftThe Journal of Clinical Pharmacology
Nummer van het tijdschrift11
StatusPublished - nov.-2018

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