Anemia is associated with an increased central venous pressure and mortality in a broad spectrum of cardiovascular patients

Lennaert Kleijn; B. Daan Westenbrink; Vincent M. van Deursen; Kevin Damman; Rudolf A. de Boer; Hans Hillege; Dirk J. van Veldhuisen; Adriaan A. Voors; Peter van der Meer

doi:10.1007/s00392-014-0673-7

Anemia is associated with an increased central venous pressure and mortality in a broad spectrum of cardiovascular patients

Lennaert Kleijn, B. Daan Westenbrink, Vincent M. van Deursen, Kevin Damman, Rudolf A. de Boer, Hans Hillege, Dirk J. van Veldhuisen, Adriaan A. Voors, Peter van der Meer^*

^*Bijbehorende auteur voor dit werk

Onderzoeksoutput › Academic › peer review

3 Citaten (Scopus)

Samenvatting

Background Anemia is frequently observed in patients with cardiovascular disease. Multiple factors have been associated with anemia, but the role of hemodynamics is largely unknown. Therefore, we investigated the association between hemoglobin (Hb) levels, hemodynamics and outcome in a broad spectrum of cardiovascular patients.

Methods and results A total of 2,009 patients who underwent right heart catheterization at the University Medical Center Groningen, the Netherlands, between 1989 and 2006 were identified and data were extracted from electronic databases. Anemia was defined by the WHO criteria (male, hemoglobin

Conclusion Anemia is common in cardiovascular patients and independently related to an elevated CVP and CI. Patients with anemia and an elevated CVP have the worst prognosis.

Originele taal-2	English
Pagina's (van-tot)	467-476
Aantal pagina's	10
Tijdschrift	Clinical Research in Cardiology
Volume	103
Nummer van het tijdschrift	6
DOI's	https://doi.org/10.1007/s00392-014-0673-7
Status	Published - jun.-2014

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Anemia is associated with an increased central venous pressure and mortality
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Kleijn, L., Westenbrink, B. D., van Deursen, V. M., Damman, K., de Boer, R. A., Hillege, H., van Veldhuisen, D. J., Voors, A. A., & van der Meer, P. (2014). Anemia is associated with an increased central venous pressure and mortality in a broad spectrum of cardiovascular patients. Clinical Research in Cardiology, 103(6), 467-476. https://doi.org/10.1007/s00392-014-0673-7

@article{59b57de6eef74794b2f03871f62f590f,

title = "Anemia is associated with an increased central venous pressure and mortality in a broad spectrum of cardiovascular patients",

abstract = "Background Anemia is frequently observed in patients with cardiovascular disease. Multiple factors have been associated with anemia, but the role of hemodynamics is largely unknown. Therefore, we investigated the association between hemoglobin (Hb) levels, hemodynamics and outcome in a broad spectrum of cardiovascular patients.Methods and results A total of 2,009 patients who underwent right heart catheterization at the University Medical Center Groningen, the Netherlands, between 1989 and 2006 were identified and data were extracted from electronic databases. Anemia was defined by the WHO criteria (male, hemoglobinConclusion Anemia is common in cardiovascular patients and independently related to an elevated CVP and CI. Patients with anemia and an elevated CVP have the worst prognosis.",

keywords = "Heart failure, Anemia, Hemoglobin, Hemodynamics, CHRONIC HEART-FAILURE, ACUTE MYOCARDIAL-INFARCTION, HEMOGLOBIN CONCENTRATION, OXYGEN AVAILABILITY, PROGNOSTIC VALUE, RENAL-FUNCTION, DYSFUNCTION, CORONARY, PATHOPHYSIOLOGY, HEMODILUTION",

author = "Lennaert Kleijn and Westenbrink, {B. Daan} and {van Deursen}, {Vincent M.} and Kevin Damman and {de Boer}, {Rudolf A.} and Hans Hillege and {van Veldhuisen}, {Dirk J.} and Voors, {Adriaan A.} and {van der Meer}, Peter",

year = "2014",

month = jun,

doi = "10.1007/s00392-014-0673-7",

language = "English",

volume = "103",

pages = "467--476",

journal = "Clinical Research in Cardiology",

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TY - JOUR

T1 - Anemia is associated with an increased central venous pressure and mortality in a broad spectrum of cardiovascular patients

AU - Kleijn, Lennaert

AU - Westenbrink, B. Daan

AU - van Deursen, Vincent M.

AU - Damman, Kevin

AU - de Boer, Rudolf A.

AU - Hillege, Hans

AU - van Veldhuisen, Dirk J.

AU - Voors, Adriaan A.

AU - van der Meer, Peter

PY - 2014/6

Y1 - 2014/6

N2 - Background Anemia is frequently observed in patients with cardiovascular disease. Multiple factors have been associated with anemia, but the role of hemodynamics is largely unknown. Therefore, we investigated the association between hemoglobin (Hb) levels, hemodynamics and outcome in a broad spectrum of cardiovascular patients.Methods and results A total of 2,009 patients who underwent right heart catheterization at the University Medical Center Groningen, the Netherlands, between 1989 and 2006 were identified and data were extracted from electronic databases. Anemia was defined by the WHO criteria (male, hemoglobinConclusion Anemia is common in cardiovascular patients and independently related to an elevated CVP and CI. Patients with anemia and an elevated CVP have the worst prognosis.

AB - Background Anemia is frequently observed in patients with cardiovascular disease. Multiple factors have been associated with anemia, but the role of hemodynamics is largely unknown. Therefore, we investigated the association between hemoglobin (Hb) levels, hemodynamics and outcome in a broad spectrum of cardiovascular patients.Methods and results A total of 2,009 patients who underwent right heart catheterization at the University Medical Center Groningen, the Netherlands, between 1989 and 2006 were identified and data were extracted from electronic databases. Anemia was defined by the WHO criteria (male, hemoglobinConclusion Anemia is common in cardiovascular patients and independently related to an elevated CVP and CI. Patients with anemia and an elevated CVP have the worst prognosis.

KW - Heart failure

KW - Anemia

KW - Hemoglobin

KW - Hemodynamics

KW - CHRONIC HEART-FAILURE

KW - ACUTE MYOCARDIAL-INFARCTION

KW - HEMOGLOBIN CONCENTRATION

KW - OXYGEN AVAILABILITY

KW - PROGNOSTIC VALUE

KW - RENAL-FUNCTION

KW - DYSFUNCTION

KW - CORONARY

KW - PATHOPHYSIOLOGY

KW - HEMODILUTION

U2 - 10.1007/s00392-014-0673-7

DO - 10.1007/s00392-014-0673-7

M3 - Article

SN - 1861-0684

VL - 103

SP - 467

EP - 476

JO - Clinical Research in Cardiology

JF - Clinical Research in Cardiology

IS - 6

ER -