Artificial nanopores and uses and methods relating thereto

Giovanni Maglia (Uitvinder), Shengli Zhang (Uitvinder)

Onderzoeksoutput: Patent

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Samenvatting

The invention relates to the field of nanopores and the use thereof in analyzing biopolymers, including polypeptides and polynucleotides. Provided is an artificial nanopore comprising a multimeric assembly of subunits, each subunit comprising (i) the transmembrane (TM) sequence of a β-barrel or α-helical pore forming protein fused to the amino acid sequence of (ii) a subunit of a ring-forming protein capable of controlling the transport of a polypeptide or polynucleotide across the TM region of the assembly.
Originele taal-2English
OctrooinummerWO2021101378
Prioriteitsdatum19/11/2019
Indieningsdatum19/11/2020
StatusPublished - 27-mei-2021

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