ATP-dependent proteases that also chaperone protein biogenesis

CK Suzuki*, M Rep, JM vanDijl, K Suda, LA Grivell, G Schatz

*Bijbehorende auteur voor dit werk

Onderzoeksoutputpeer review

201 Citaten (Scopus)

Samenvatting

The ATP-dependent proteases Clp and FtsH from bacteria, as well as mitochondrial homologs of FtsH and Lon from yeast, may act as chaperones; they mediate not only proteolysis, but also the insertion of proteins into membranes and the disassembly or oligomerization of protein complexes. The coordination of such processes with selective proteolysis may function in the quality control of protein biogenesis.

Originele taal-2English
Pagina's (van-tot)118-123
Aantal pagina's6
TijdschriftTrends in Biochemical Sciences
Volume22
Nummer van het tijdschrift4
StatusPublished - apr-1997

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